Chapter 6: Enzymes Flashcards Preview

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Flashcards in Chapter 6: Enzymes Deck (9)
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1
Q

enzymes catalyze rxns in an ____

A

active site

2
Q

info about active sites

A

3D cleft formed by multiple parts of aa sequence

H2O usually excluded unless a reactant

determines substrate specificity

3
Q

binding interactions between the active site and enzyme are maximized in the ____

A

transition state

4
Q

types of catalysis

A

acid/base

covalent

metal ion/cofactor

5
Q

acid/base catalysis aas

A

K, D, E, H, R, S, T, C

6
Q

covalent catalysis

A

covalent enzyme substrate intermediate

7
Q

metal ion/cofactor catalysis

A

active site binds cofactor that catalyzes rxn

8
Q

4 things needed for catalysis

A

nucleophile

t.s. stabilizer

orientation clamp

specificity

9
Q

what does a protease do

A

catalyze hydrolysis of peptide bonds

works at pH 7, 1/2 life is 1000 yrs