Chapter 6 (Exam 2) Flashcards

(51 cards)

1
Q

What are the 4 shared traits of all muscle tissue types?

A

Excitability, Contractility, Extensibility, Elasticity

These properties allow muscle tissues to play essential roles in posture, movement, circulation, digestion, and more.

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2
Q

What are the unique characteristics of skeletal muscle?

A

Voluntary control, Striated appearance, Multinucleated, Attached to bones via tendons, Fast contractions

Examples include biceps brachii, hamstrings, and deltoid.

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3
Q

What are the unique characteristics of cardiac muscle?

A

Involuntary, Striated, Single nucleus, Branched fibers with intercalated discs, Found only in the heart

Cardiac muscle contracts rhythmically and is self-excitable.

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4
Q

What are the unique characteristics of smooth muscle?

A

Involuntary, Non-striated, Spindle-shaped cells, Single nucleus, Located in walls of hollow organs

Contracts slowly and rhythmically, controlled by the autonomic nervous system and hormones.

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5
Q

How do antagonistic and synergistic muscles function?

A

Antagonistic muscles perform opposite movements; Synergistic muscles assist the prime mover

Example: Biceps (flexes elbow) vs. Triceps (extends elbow); Brachialis helps biceps during elbow flexion.

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6
Q

What is the structural organization of skeletal muscle?

A

Myofilaments → Myofibrils → Muscle fibers → Fascicles → Whole muscle

Surrounded by connective tissue layers: Endomysium, Perimysium, Epimysium.

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7
Q

What is the sarcomere and its key components?

A

The basic contractile unit of a muscle fiber located between Z-lines; Key bands/zones: A-band, I-band, H-zone, M-line

During contraction, Z-lines get closer, sarcomere shortens, and I-band & H-zone narrow.

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8
Q

Describe the sliding filament mechanism.

A

Calcium binds troponin → Tropomyosin shifts → Myosin heads bind to actin → Power stroke occurs → ATP detaches myosin

This cycle repeats as long as calcium and ATP are present.

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9
Q

How does a motor neuron activate a muscle fiber?

A

An action potential travels down a motor neuron; ACh released at the neuromuscular junction; Signal travels down T-tubules; Calcium released

Calcium initiates the contraction cycle.

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10
Q

What is the role of calcium in contraction?

A

Ca²⁺ binds to troponin, shifts tropomyosin, exposes actin’s binding sites

Myosin can now bind to actin; Calcium is pumped back into the SR for relaxation.

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11
Q

What are actin, myosin, troponin, and tropomyosin?

A

Actin: Thin filament; Myosin: Thick filament; Troponin: Binds calcium; Tropomyosin: Blocks actin’s binding sites

Troponin moves tropomyosin off actin during contraction.

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12
Q

What is the role of transverse (T) tubules?

A

Extensions of the sarcolemma that carry electrical signals deep into the muscle fiber

They trigger calcium release from the SR across the fiber.

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13
Q

What is ATP’s role in the sliding filament model?

A

Detaches myosin from actin, Hydrolyzes to reset myosin head, Powers calcium pumps in the SR

Without ATP, muscles go into rigor mortis.

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14
Q

What is the function of acetylcholine (ACh)?

A

A neurotransmitter released by motor neurons; Binds to receptors on muscle membrane

Acetylcholinesterase breaks down ACh to end stimulation.

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15
Q

What is Duchenne Muscular Dystrophy (DMD)?

A

A severe X-linked genetic disorder primarily affecting boys; Caused by absence of dystrophin

Leads to muscle fiber damage and symptoms like muscle weakness and loss of mobility.

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16
Q

What is a motor unit?

A

One motor neuron and all the muscle fibers it controls; Fewer fibers = fine control; More fibers = gross movement

Recruitment increases contraction strength.

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17
Q

What is the difference between a muscle twitch and tetanus?

A

Twitch: brief, single contraction; Tetanus: sustained, maximal contraction from rapid stimulation

Holding a weight continuously requires tetanus.

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18
Q

What is summation in muscle contraction?

A

Occurs when a second stimulus arrives before the first twitch is over; Creates a stronger force

This leads to tetanus if stimuli are rapid.

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19
Q

What are the four energy sources for muscle contraction?

A
  • Stored ATP
  • Creatine phosphate
  • Anaerobic respiration
  • Aerobic respiration

Each provides energy for different durations and intensities.

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20
Q

What is oxygen debt and how is it corrected?

A

Extra oxygen required after exercise to restore muscle cells; Used to replenish ATP and creatine phosphate, convert lactic acid

Reload oxygen onto myoglobin.

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21
Q

Compare slow-twitch and fast-twitch muscle fibers.

A
  • Slow-twitch (Type I): Aerobic, fatigue-resistant, suited for endurance
  • Fast-twitch (Type II): Anaerobic, rapid contractions, fatigue quickly

Examples: long-distance running vs. sprinting.

22
Q

What roles do different muscle types play in exercise and endurance?

A
  • Skeletal muscle: Main driver of movement
  • Cardiac muscle: Becomes more efficient with aerobic training
  • Smooth muscle: Regulates blood flow and digestion

Not directly involved in skeletal movement.

23
Q

What are the benefits of aerobic exercise?

A
  • Increases mitochondria and capillary density
  • Improves cardiovascular and respiratory efficiency
  • Reduces resting heart rate

Examples: running, swimming, cycling.

24
Q

What are the benefits of resistance exercise?

A
  • Increases muscle mass
  • Improves bone density
  • Enhances metabolic rate

Examples: weightlifting, push-ups.

25
What are synergistic muscles?
Muscles that assist the prime mover during a movement ## Footnote Example: brachialis assists biceps brachii.
26
What are antagonistic muscles?
Pairs of muscles that produce opposite movements ## Footnote Example: biceps (flexion) vs. triceps (extension).
27
What is a tendon?
A connective tissue that attaches muscle to bone ## Footnote Transmits force for movement.
28
What is the origin of a muscle?
The fixed attachment point of a muscle that does not move during contraction
29
What is the insertion of a muscle?
The movable attachment of a muscle; it’s the bone that moves during contraction
30
What is tendinitis?
Inflammation of a tendon, usually from overuse or strain ## Footnote Causes pain and limited motion.
31
What is a sprain?
Ligament injury from overstretching or tearing ## Footnote Often affects ankles and wrists.
32
What is a strain?
Muscle or tendon injury, commonly from overstretching or improper lifting
33
What is a sarcomere?
The basic functional unit of a muscle fiber ## Footnote Contains actin and myosin for contraction.
34
What is a muscle fiber?
A single muscle cell; multinucleated in skeletal muscle; contains many myofibrils
35
What is a myofibril?
A long, rod-like structure in muscle fibers made up of repeating sarcomeres
36
What is a fascicle?
A bundle of muscle fibers wrapped in connective tissue (perimysium)
37
What is troponin?
A protein that binds calcium and moves tropomyosin off actin during contraction
38
What is tropomyosin?
A protein that blocks myosin-binding sites on actin at rest
39
What is actin?
A thin filament in sarcomeres that myosin pulls on to shorten the muscle
40
What is myosin?
A thick filament with heads that bind to actin to produce contraction
41
What is the neuromuscular junction?
The synapse between a motor neuron and a muscle fiber
42
What is acetylcholine (ACh)?
A neurotransmitter that signals muscles to contract by binding to sarcolemma receptors
43
What is muscular dystrophy?
A group of genetic disorders causing muscle weakening; DMD is the most common
44
What is recruitment?
Gradual activation of more motor units to increase contraction strength
45
What is a muscle twitch?
A brief contraction caused by a single action potential
46
What is summation?
Increased force of contraction due to multiple stimuli arriving close together
47
What is tetanus (in muscle)?
A sustained, maximal contraction caused by high-frequency stimulation
48
What is oxygen debt?
The extra oxygen needed after intense activity to restore homeostasis
49
What is aerobic exercise?
Exercise that uses oxygen for sustained energy production; Improves heart, lungs, and endurance
50
What is resistance exercise?
Exercise involving overcoming resistance, which builds strength and muscle size
51
What is DOMS (Delayed Onset Muscle Soreness)?
Muscle pain or stiffness 24–72 hours after exercise, due to microtears and inflammation