Flashcards in Chapter 6:: Skin Glands: Sebaceous, Eccrine, and Apocrine Glands Deck (11)
The periphery of the sebaceous gland is a basal cell layer composed of small, _____, _______, ________.
cuboidal, nucleated, highly mitotic sebocytes
A sebaceous gland associated with a hair follicle is termed a _______.
The hairs associated with these large glands are often tiny, and the total structure is more specifically termed ______, being a pilosebaceous unit variant, the other two being the ______ and the ______.
sebaceous follicles, terminal hair follicle, vellus hair follicle
The earliest known signal necessary for sebaceous gland development is _____
Antagonizing _______signaling constitutes an impor- tant prerequisite for normal sebaceous differentiation in postnatal skin tissue.
The sebaceous glands exude lipids by disintegration of entire cells, a process known as _________.
Sebaceous glands require ________ stimulation to produce significant quantities of sebum.
The weak adrenal androgen, ___________, is probably a significant regulator of sebaceous gland activity through its conversion to testosterone
dehydroepiandros- terone sulfate (DHEAS)
___________ is the most potent pharmacologic inhibitor of sebum secretion.
___________ may reduce sebaceous lipid synthesis and as such may be useful in the treatment of acne.
PPAR-α agonists and PPAR-γ antagonists