Chapter 7

Question 1

SN1 or SN2?

• One step and the reaction is over
• two steps with an intermediate

Answer 1

SN2

SN1

Question 2

Equilibrium favors the side with the more stable __________.

Answer 2

Conjugate base

Question 3

During the substitution, one group _________ and one group _______.

Answer 3

Attacks, leaves

Question 4

 The electronegative leaving group creates a partial charge on the site of attack to attract the….

Answer 4

Negative charge of the nucleophile

Question 5

The amount of ___________ at the alpha carbon affects the reaction mechanism

Answer 5

Branching

Question 6

Every nucleophilic substitution reaction will involve….

Answer 6

Nucleophilic attack and the loss of a leaving group!

Question 7

SN2 reactions are a concerted mechanism, meaning….

Answer 7

They happen at the same time
***2nd order
Rate=k [substrate] [nucleophile{

Question 8

What does SN2 stand for?

Answer 8

Substrate
Nucleophile
Biomolecular

-100% inversion

Question 9

SN2 reactions, the nucleophile attacks from the…..

Answer 9

Back-side (always!)

Question 10

What is the rate law for SN1?

Answer 10

Rate = k [substrate]

Question 11

A two-step mechanism gives a diagram with _____ transition states.

Answer 11

Two

Question 12

For a SN2 reaction…
If the nucleophile was tripled, how would the rate be affected?

For SN1, if the  nucleophile was tripled how would the rate be affected?

Answer 12

Tripled because first order

No change, rate = k [substrate]

Question 13

Will a 3 degree substrate have a faster rate or a second-degree have a faster rate for SN1 reactions?

Answer 13

third degree because the Cabocation is more stable (less activation energy needed)