Chapter 7 Flashcards

1
Q

What are the base pairing rules for DNA?

A

Cytosine with guanine and Adine with thymine

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2
Q

What is purine?

A

Nitrogen bases with two rings.

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3
Q

What is pyrimidine?

A

Nitrogen bases with one ring

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4
Q

In regards to nitrogen bases, explain why each ring of the DNA ladder is the same size.

A

The way they connect each pair as uniform in length.

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5
Q

Why is it important that covalent bonds hold the backbone together and hydrogen bonds hold the nitrogen bases together?

A

So they can hold individual strands together securely.

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6
Q

Who won the Nobel prize for the discovery of DNA’s structure?

A

Rosalind Franklin‘s research was not credited when they stole copies of her work.

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7
Q

Why is DNA replication “semi-conservative?”

A

It will replicate half the double helix and find a new mate partner.

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8
Q

Explain the process of DNA replication

A

Replication is when the double helix starts unwinding. The origin of replication does is followed to where single strand protein stabilize it. The replication fork assist the process with extreme accuracy.

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9
Q

Explain Helicase

A

It unwinds parental double helix.

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10
Q

Explain DNA polymerase

A

Synthesizes strands of DNA

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11
Q

Explain DNA ligase

A

Joins Okazaki fragment

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12
Q

Explain RNA polymerase

A

Synthesizes an RNA primer

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13
Q

Explain the difference between the leading strand and lagging strand and DNA replication.

A

Leading strand is smoother than the lagging strand

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14
Q

What is Okazaki fragment?

A

Short stretch of DNA made during replication

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15
Q

Why is RNA important?

A

Because it carries genetic information from DNA to ribosomes

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16
Q

Explain what happens in the process of transcription and translation

A

MRNA travels to the cytoplasm from the nucleus

17
Q

Complete the following Venn diagram, including seven total details

18
Q

Show the products of transcription and translation in the example below. Use the DNA sequence to make the complementary mRNA strand. Create the IRNA anticodon that will attach to the mRNA. Use the mRNA strand and codon chart to determine the amino acid sequence.

A

DNA equals
TACCGGGATAATCAAGGGCGATTCGTTAA
mRNA equals
AUGGCCCUAUUAGUUCCCGCUAAGCCAAUU
TRNA equals
UACCGGGATAATCCAAGGGCGAUUCGGUUAA
Amino acid equals
MET ALA LEU LEU VAL PRO ALA LYS PRO IIE

19
Q

Why is a codon chart used in

A

It is a reference tool for a genetic code

20
Q

what is a mutation?

A

Permanent changes in data sequence

21
Q

The majority of mutations are

A

Harmful or meaningless

22
Q

List three examples of mutagens

A

X-rays, UV light, chemicals

23
Q

How can mutations occur?

A

Spontaneous or when DNA is exposed to mutagens.

24
Q

What is a point mutation

A

A mutation affecting only one or very few nucleotides in a gene sequence

25
Describe base substitution
Replacement of one base by another
26
And explain or describe insertion
Addition of one or more nucleotides
27
Explain deletion
Removal of one or more nucleotides
28
What is chromosomal mutation?
It can change relatively large regions of chromosomes
29
What is deficiency?
Delineation are larger than a few nucleotides
30
Describe translocation
Part of one chromosome that is more of another chromosome
31
Describe inversion
Segment of chromosome is over 1800 normal orientation.
32
Explain duplication
Part of chromosomes that show up twice
33
Explain ANEUPLOIDY
Trysomy or monosomy
34
Draw-insert a picture of DNA ladder with9 rungs on separate paper and label each part. Use the following labels: Sugar Phosphate Nitrogen bases: adenine, thymine, guanine, cytosine Hydrogen bond Covalent bond
35