Chapter 7: Capsules Flashcards Preview

πŸ“‹ PHAR 3: Pharmaceutical Dosage Forms > Chapter 7: Capsules > Flashcards

Flashcards in Chapter 7: Capsules Deck (26)
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1
Q

They are made of gelatin to which glycerin or a polyhydric alcohol.

A

soft gelatin capsules

2
Q

An example of polyhydric alcohol

A

sorbitol

3
Q

They contain more moisture than hard capsules.

A

soft gelatin capsules

4
Q

Moisture content of soft-gelatin capsules

A

6-10%

5
Q

They may contain preservatives.

A

soft gelatin capsules

6
Q

Examples of preservatives

A

methylparaben,

propylparaben

7
Q

This is used to retard microbial growth.

A

preservatives

8
Q

They may be oblong, oval or round.

A

soft gelatin capsules

9
Q

They are used to encapsulate and hermetically seal liquids, suspensions, pasty materials, dry powders, and even preformed tablets.

A

soft gelatin capsules

10
Q

They are pharmaceutically elegant and easily swallowed.

A

soft gelatin capsules

11
Q

Three methods of preparation of soft gelatin capsules

A

plate process,
rotary die process,
reciprocating die process

12
Q

In this process of preparation of soft gelatin capsules, a warm sheet of plain or colored gelatin isplaced on the bottom plate of the mold andthe medication-containing liquid is evenlypoured on it.

A

plate process

13
Q

In this process of preparation of soft gelatin capsules, liquid a gelatin flowing from an overhead tank is formed into two continuous ribbons by the rotary die machine and brought together between twin rotating dies.

A

soft gelatin capsules

14
Q

He developed rotary die process.

A

Robert Scherer

15
Q

This process of preparation of soft gelatin capsules is similar to the rotary die process in that ribbons of gelatin are formed and used to encapsulate the fill but it differs in the encapsulating process.

A

reciprocating die process

16
Q

Soft gelatin capsules are prepared to contain a variety of ___, ___, and ___.

A

liquid,
paste,
dry fills

17
Q

Liquids that may be encapsulated into soft gelatin capsules include:

A

water-immiscible volatile and non-volatile liquids,
water-miscible non-volatile liquids,
water-miscible and relatively non-volatile compounds

18
Q

vegetable and aromatic oils

A

water-immiscible volatile and non-volatile liquids

19
Q

aromatic and aliphatic hydrocarbon

A

water-immiscible volatile and non-volatile liquids

20
Q

chlorinated hydrocarbons

A

water-immiscible volatile and non-volatile liquids

21
Q

ethers

A

water-immiscible volatile and non-volatile liquids

22
Q

esters

A

water-immiscible volatile and non-volatile liquids

23
Q

alcohols

A

water-immiscible volatile and non-volatile liquids

24
Q

organic acids

A

water-immiscible volatile and non-volatile liquids

25
Q

polyethylene glycols

A

water-miscible non-volatile liquids

26
Q

polysorbate 80

A

water-miscible non-volatile liquids