Chapter 7 Set 8

Question 1

When would CMI occur as opposed to AMI?

Answer 1

CMI deals with pathogens that have already entered cells.

Question 2

What are T-Cells where are they made and mature, and what are they involved in?

Answer 2

T-Cells
Made in bone marrow
Mature in Thymus
Move to lymphoid tissues and blood
Involved in cell-mediated immunity

Question 3

What are the 4 types of T-Cells?

Answer 3

Killer T-Cells
Suppressor T-Cells
Helper T-Cells
Memory T-Cells

Question 4

What is the 1st step in CMI? (Production)

Answer 4

T-cells (T-lymphocytes) in lymphoid tissue.

Question 5

What is the 2nd step in CMI?

Answer 5

APC has engulfed pathogen and presents antigen to one type of T-cell.

Question 6

What is the 3rd step in CMI?

Answer 6

T-cell is sensitised, enlarges and divides.

Question 7

What is the 4th step in CMI?

Answer 7

Many clones of the T-cell are produced, sensitised for the antigen that was presented.

Question 8

What do Killer T-Cells do?

Answer 8

Cells that have been infected have markers on their surface.
Killer T-Cells move to sites of infection
Attach to infected or foreign cells and destroy them.

Question 9

What do Suppressor T-Cells do?

Answer 9

Stop action of Killer T-Cells once infected cells have been destroyed.

Question 10

What do Helper T-Cells do?

Answer 10

Secrete substances that sensitise more lymphocytes, attract macrophages and enhance macrophage activity.

Question 11

What do Memory T-Cells do?

Answer 11

Remain sensitised to the specific pathogen, in circulation and tissues, so that future responses to the pathogen are much more rapid.