Chapter 71 - Acquired Perforating Disorders Flashcards
TABLE 71-3
Presentations of Acquired Perforating Dermatosis
Disorder
Age of onset
4th decade (average)
Kyrle Disease/Acquired Perforating Collagenosis
TABLE 71-3
Presentations of Acquired Perforating Dermatosis
Disorder
Age of onset
3rd decade (average)
Perforating Folliculitis
TABLE 71-3
Presentations of Acquired Perforating Dermatosis
Disorder
Age of onset
2nd decade (average)
Acquired Elastosis Perforans Serpiginosa
TABLE 71-3
Presentations of Acquired Perforating Dermatosis
Disorder
Site
Extensor lower and upper extremities; head, neck, and trunk
Kyrle Disease/Acquired Perforating Collagenosis
TABLE 71-3
Presentations of Acquired Perforating Dermatosis
Disorder
Site
Hair-bearing portions of extremities
Perforating Folliculitis
TABLE 71-3
Presentations of Acquired Perforating Dermatosis
Disorder
Site
Nape of neck; upper extremities; face; lower extremities
Acquired Elastosis Perforans Serpiginosa
TABLE 71-3
Presentations of Acquired Perforating Dermatosis
Disorder
Cutaneous findings
Round, umbilicated, skin-colored, erythematous or hyperpigmented papules and nodules with a central crust or keratotic plug
Kyrle Disease/Acquired Perforating Collagenosis
TABLE 71-3
Presentations of Acquired Perforating Dermatosis
Disorder
Cutaneous findings
Similar to Kyrle disease/acquired perforating collagenosis, but with follicular distribution and variable central crusting
Perforating Folliculitis
TABLE 71-3
Presentations of Acquired Perforating Dermatosis
Disorder
Cutaneous findings
Papules in serpiginous configuration with central atrophy
Acquired Elastosis Perforans Serpiginosa
TABLE 71-3
Presentations of Acquired Perforating Dermatosis
Disorder
Disease associations
Renal failure, hemodialysis, diabetes mellitus, hepatic insufficiency
Kyrle Disease/Acquired Perforating Collagenosis
TABLE 71-3
Presentations of Acquired Perforating Dermatosis
Disorder
Disease associations
Idiopathic, minor association with renal failure, hemodialysis, diabetes mellitus
Perforating Folliculitis
TABLE 71-3
Presentations of Acquired Perforating Dermatosis
Disorder
Disease associations
Down syndrome; Ehlers-Danlos syndrome; osteogenesis imperfecta; pseudoxanthoma elasticum; minor association with renal failure
Acquired Elastosis Perforans Serpiginosa
TABLE 71-3
Presentations of Acquired Perforating Dermatosis
Disorder
Koebner phenomenon
Positive
Kyrle Disease/Acquired Perforating Collagenosis
TABLE 71-3
Presentations of Acquired Perforating Dermatosis
Disorder
Koebner phenomenon
Negative
Perforating Folliculitis
TABLE 71-3
Presentations of Acquired Perforating Dermatosis
Disorder
Koebner phenomenon
Occasionally
Acquired Elastosis Perforans Serpiginosa
TABLE 71-6
Treatment of Acquired Perforating Dermatosis
First-line therapy (7)
- Retinoic acid
- Tretinoin
- Tazarotene
- Beclomethasone
- Triamcinolone acetonide
- UVB
- NUVB
TABLE 71-6
Treatment of Acquired Perforating Dermatosis
Second-line therapy (4)
- Isotretinoin
- Acitretin
- Allopurinol
- PUVA
TABLE 71-6
Treatment of Acquired Perforating Dermatosis
DOSING
Retinoic acid
0.025% gel
TABLE 71-6
Treatment of Acquired Perforating Dermatosis
DOSING
Tretinoin
0.1% cream 1-3 times daily
TABLE 71-6
Treatment of Acquired Perforating Dermatosis
DOSING
Tazarotene
0.1% gel daily
TABLE 71-6
Treatment of Acquired Perforating Dermatosis
DOSING
Beclomethasone
0.1% cream
TABLE 71-6
Treatment of Acquired Perforating Dermatosis
DOSING
Triamcinolone acetonide
10 mg/mL intralesional injection
TABLE 71-6
Treatment of Acquired Perforating Dermatosis
DOSING
Isotretinoin
0.5 mg/kg/day
TABLE 71-6
Treatment of Acquired Perforating Dermatosis
DOSING
Acitretin
25-30 mg daily
