chapter 8 study guide Flashcards

(39 cards)

1
Q

What was Frederick Griffith investigating when he noticed only one type of bacterium killed the mice studied?

A

bacterium that cause pneumonia

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2
Q

Which type of bacterium killed the mice injected? Which bacterium did not?

A

S-type, R-type

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3
Q

What was Griffith’s conclusion after mice were injected with a combination of heat-killed S-type and live R-type bacterium, but still died?

A

Some type of “material” was transferred from the S-type to R-type

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4
Q

What did Griffith label this mystery material?

A

Transforming principle

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5
Q

What did Oswald Avery & his team add to bacterium extract to show DNA was the “transforming principle?

A

enzyme that specifically destroyed DNA

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6
Q

What type of virus did biologists Hershey and Chase use to prove that genetic material was made of DNA?

A

bacteriophage

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7
Q

To prove DNA was being transferred from virus to host, Hershey and Chase tagged DNA with what?

A

Radioactive phosphorus/radioactive isotopes

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8
Q

What are the monomers that make up a DNA molecule called? What are their three parts?

A

Nucleotides;
phosphate group, deoxyribose, nitrogen-containing base

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9
Q

How many nucleotides make up a molecule of DNA? What is their only difference?

A

Four,Their nitrogen-containing base

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10
Q

List the four nucleotides found in DNA?

A

Cytosine, Thymine, Adenine, Guanine

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11
Q

What was Chargaff’s major discovery?

A

DNA arrangement was different for different organisms

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12
Q

What type of scientists were Watson and Crick? What was there major discovery regarding DNA?

A

Geneticist and physicist, The 3-dimensional double helix structure of DNA

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13
Q

What type of bonds hold DNA together? What type of bonds hold nucleotide bases
together?

A

covalent bonds, hydrogen bonds

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14
Q

What term is given to the principle that DNA strands are complimentary?

A

Base-pairing rules

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15
Q

What can be figured out if the base sequence of one strand of the DNA double helix is known?

A

The sequence
of the other strand

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16
Q

What assurance does DNA replication provide for an organism?

A

That every cell has a complete set of
identical genetic information

17
Q

Name the only function of DNA?

A

Storing information

18
Q

What does the actual work of DNA replication?

A

Enzymes and other proteins

19
Q

What is the end result of the group of enzymes DNA polymerase “acting” on an “unzipped” DNA strand?

A

Two complete molecules of identical DNA

20
Q

Which type of bonds must be broken for DNA polymerase to “unzip” the double helix?

A

Hydrogen bonds

21
Q

What pairs with the exposed bases as the template strand “unzips”?

A

free nucleotides

22
Q

What happens when DNA polymerases bond the nucleotides together?

A

They form a new complementary
strand

23
Q

What is the end result of the DNA replication process?

A

Two identical molecules of DNA

24
Q

How fast does DNA replication happen? How long does complete replication take?

A

Very quickly, A few hours

25
What function does DNA polymerase have to detect, remove, and replace nucleotide errors?
“proofreading”
26
Who defined the central dogma of molecular biology?
Francis Crick
27
In which way does information flow?
From DNA to RNA to proteins
28
What does DNA transcription converts a DNA message into?
RNA
29
Where does DNA translation occur in eukaryotes? What about replication and transcription?
In the cytoplasm of the cell , In the nucleus
30
What does RNA act as between DNA in the nucleus and protein synthesis in the cytoplasm?
An intermediate link
31
What is the main difference between RNA nucleotides and DNA nucleotides?
RNA has the base Uracil in place of Thymine
32
How many strands of nucleotides is RNA? How many is DNA?
Single strand,Double strand
33
What is DNA transcription catalyzed by?
RNA polymerase
34
List the three parts of Step 1 of DNA transcription.
RNA polymerase recognizes the transcription start site of a gene; assembles on the DNA strand; unwinds a segment of the DNA molecule
35
What are the three major types of RNA molecules? Which type delivers amino acids?
Messenger, Ribosomal, &Transfer, Transfer RNA
36
What is the mRNA message converted into during DNA translation?
A polypeptide used to build proteins
37
What does DNA coding provide the cell with instructions for?
How to use amino acids to build proteins
38
What are the three types of codons used in the process of DNA translation?
Start, regular, and stop
39
Where in the cell does the process of translating a codon into an amino acid occur?
The ribosome of a cell’s cytoplasm