Chapter One — Overview Flashcards

(51 cards)

1
Q

Neuron

A

nerve cell that is the basic building block of the nervous system, specialized to transmit information throughout the body

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2
Q

Neuroglia

A

non-neuronal cells that maintain homeostasis, form myelin, and provide support and protection for neurons in the brain, and for neurons in other parts of the nervous system such as in the autonomic nervous system.

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3
Q

Functions of glial cells

A

to surround neurons and hold them in place, to supply nutrients and oxygen to neurons, to insulate one neuron from another, and to destroy pathogens and remove dead neurons.

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4
Q

Dendrite

A

the branched projections of a neuron that act to conduct the electrochemical stimulation received from other neural cells to the cell body, or soma, of the neuron from which the dendrites project.

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5
Q

Soma

A

cell body; the bulbous end of a neuron, containing the cell nucleus

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6
Q

Axon

A

long, slender projection of a nerve cell, or neuron, that typically conducts electrical impulses away from the neuron’s cell body

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7
Q

Morphological differences between axons and dendrites

A

dendrites often taper while axons usually maintain a constant radius

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8
Q

Functional differences between axons and dendrites.

A

dendrites usually receive signals while axons usually transmit them

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9
Q

Size difference between axon and dendrite

A

dendrites are restricted to a small region around the cell body while axons can be much longer

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10
Q

Synapse

A

structure that permits a neuron to pass an electrical or chemical signal to another cell

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11
Q

Chemical synapse

A

In a chemical synapse, the presynaptic neuron releases a chemical called a neurotransmitter that binds to receptors located in the postsynaptic cell, usually embedded in the plasma membrane.

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12
Q

Electrical synapse

A

In an electrical synapse, the presynaptic and postsynaptic cell membranes are connected by special channels called gap junctions that are capable of passing electric current, causing voltage changes in the presynaptic cell to induce voltage changes in the postsynaptic cell.

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13
Q

Neurotransmitter

A

Neurotransmitters are endogenous chemicals that transmit signals from a neuron to a target cell across a synapse.

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14
Q

3-Step Neurotransmitter Process

A

Neurotransmitters are packaged into synaptic vesicles clustered beneath the membrane in the axon terminal, on the presynaptic side of a synapse. Following an action potential, they are released into and diffuse across the synaptic cleft, where they bind to specific receptors in the membrane on the postsynaptic side of the synapse.

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15
Q

Action potential

A

action potential is a short-lasting event in which the electrical membrane potential of a cell rapidly rises and falls, following a consistent trajectory

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16
Q

stores various neurotransmitters that are released at the synapse.

A

Synaptic vesicle

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17
Q

a temporary depolarization of postsynaptic membrane potential caused by the flow of positively charged ions into the postsynaptic cell as a result of opening of ligand-sensitive channels

A

excitatory postsynaptic potential

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18
Q

excitatory postsynaptic potential

A

temporary depolarization of postsynaptic membrane potential caused by the flow of positively charged ions into the postsynaptic cell as a result of opening of ligand-sensitive channels

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19
Q

All or none principle

A

The amplitude of an action potential is independent of the amount of current that produced it.

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20
Q

Axon hillock

A

The axon hillock is a specialized part of the cell body (or soma) of a neuron that connects to the axon. As a result, the axon hillock is the last site in the soma where membrane potentials propagated from synaptic inputs are summated before being transmitted to the axon.

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21
Q

Interneuron, Local circuit neuron

A

a neuron that forms a connection between other neurons

22
Q

Function of myelin

A

The fat helps to insulate the axons from electrically charged atoms and ions. The main purpose of a myelin layer (or sheath) is to increase the speed at which impulses propagate along the myelinated fiber. Myelin helps prevent the electrical current from leaving the axon.

23
Q

Main types of neuroglia (3)

A

Astrocytes, oligodendrocytes, microglial cells

24
Q

Astrocytes (Shape, Prevalence, Major functions)

A

characteristic star-shaped glial cells in the brain and spinal cord. They are the most abundant cell of the human brain. They perform many functions, including biochemical support of endothelial cells that form the blood–brain barrier, provision of nutrients to the nervous tissue, maintenance of extracellular ion balance, and a role in the repair and scarring process of the brain and spinal cord following traumatic injuries.

25
Blood-brain barrier
a separation of circulating blood from the brain extracellular fluid (BECF) in the central nervous system (CNS)
26
Oligodendrocytes
Their main functions are to provide support and to insulate the axons (the long projection of nerve cells) in the central nervous system (the brain and spinal cord) of some vertebrates. Oligodendrocytes do this by creating the myelin sheath, which is 80% lipid and 20% protein.
27
Schwann Cells (neurolemmocytes)
Schwann cells or neurolemmocytes are the principal glia of the peripheral nervous system (PNS). They are involved in PNS myelination.
28
Microglia
a type of glial cell that are the resident macrophages of the brain and spinal cord, and thus act as the first and main form of active immune defense in the central nervous system (CNS). Microglia are constantly scavenging the CNS for damaged neurons, plaques, and infectious agents.
29
Neural circuit
a functional entity of interconnected neurons that is able to regulate its own activity using a feedback loop (similar to a control loop in cybernetics).
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Summation
Summation, also known as frequency summation is the method of signal transduction between neurons, which determines whether or not an action potential will be triggered by the summation of postsynaptic potentials.
31
Neuropil
Neuropil, sometimes referred to as "neuropile," is a broad term defined as any area in the nervous system composed of mostly unmyelinated axons, dendrites and glial cell processes that forms a synaptically dense region containing a relatively low number of cell bodies.
32
afferent neurons
carry nerve impulses from receptors or sense organs towards the central nervous system
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efferent neurons
efferent nerves, otherwise known as motor or effector neurons, carry nerve impulses away from the central nervous system to effectors such as muscles or glands (and also the ciliated cells of the inner ear).
34
Central nervous system
the part of the nervous system that integrates the information that it receives from, and coordinates the activity of, all parts of the bodies of bilaterian animals; consists of the brain and the spinal cord. Some classifications also include the retina and the cranial nerves in the CNS.
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Cranial nerve
Cranial nerves are nerves that emerge directly from the brain, in contrast to spinal nerves, which emerge from segments of the spinal cord. In humans, there are traditionally twelve pairs of cranial nerves.
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Spinal cord
The spinal cord is a long, thin, tubular bundle of nervous tissue and support cells that extends from the brain (the medulla oblongata specifically).
37
Peripheral nervous system
The peripheral nervous system (PNS, or occasionally PeNS) consists of the nerves and ganglia outside of the brain and spinal cord. The main function of the PNS is to connect the central nervous system (CNS) to the limbs and organs
38
Somatic nervous system
The somatic nervous system (SoNS or voluntary nervous system) is the part of the peripheral nervous system associated with the voluntary control of body movements via skeletal muscles. The SoNS consists of efferent nerves responsible for stimulating muscle contraction, including all the non sensory neurons connected with skeletal muscles and skin.
39
Autonomic nervous system
The autonomic nervous system (ANS or visceral nervous system or involuntary nervous system) is the part of the peripheral nervous system that acts as a control system functioning largely below the level of consciousness, and controls visceral functions.
40
Parasympathetic nervous system
Part of autonomic nervous system responsible for stimulation of "rest-and-digest" activities that occur when the body is at rest, including sexual arousal, salivation, lacrimation (tears), urination, digestion, and defecation.
41
Sympathetic nervous system
part of autonomic nervous system; general action is to mobilize the body's nervous system fight-or-flight response. It is, however, constantly active at a basic level to maintain homeostasis.
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Ganglion
mass of nerve cell bodies
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Nerve
A nerve, is an enclosed, cable-like bundle of axons (the long, slender projections of neurons) in the peripheral nervous system.
44
Nucleus (neuroanatomy)
a brain structure consisting of a relatively compact cluster of neurons. It is one of the two most common forms of nerve cell organization, the other being layered structures such as the cerebral cortex or cerebellar cortex. In anatomical sections, a nucleus shows up as a region of gray matter, often bordered by white matter.
45
Cortex
a sheet-like array of neurons
46
Tract
A neural pathway, neural tract, or neural face, connects one part of the nervous system with another and usually consists of bundles of elongated, myelin-insulated neurons, known collectively as white matter. Neural pathways serve to connect relatively distant areas of the brain or nervous system, compared to the local communication of grey matter. Compare to nerves in PNS.
47
Commisure
a tract that passes the midline of the brain
48
Gray matter
White matter is one of the two components of the central nervous system and consists mostly of glial cells and myelinated axons (the tracts/commisures) that transmit signals from one region of the cerebrum to another and between the cerebrum and lower brain centers.
49
Grey matter
Grey matter (or gray matter) is a major component of the central nervous system, consisting of neuronal cell bodies, neuropil (dendrites and unmyelinated axons), glial cells (astroglia and oligodendrocytes) and capillaries. Grey matter contains neural cell bodies, in contrast to white matter, which does not and mostly contains myelinated axon tracts.
50
Autonomic ganglion
Autonomic ganglia are clusters of neuronal cell bodies and their dendrites and are essentially a junction between autonomic nerves originating from the central nervous system and autonomic nerves innervating their target organs in the periphery.
51
Enteric nervous system
The enteric nervous system (ENS) is a subdivision of the autonomic nervous system (ANS) that directly controls the gastrointestinal system in vertebrates.