Chapter One — Overview Flashcards
(51 cards)
Neuron
nerve cell that is the basic building block of the nervous system, specialized to transmit information throughout the body
Neuroglia
non-neuronal cells that maintain homeostasis, form myelin, and provide support and protection for neurons in the brain, and for neurons in other parts of the nervous system such as in the autonomic nervous system.
Functions of glial cells
to surround neurons and hold them in place, to supply nutrients and oxygen to neurons, to insulate one neuron from another, and to destroy pathogens and remove dead neurons.
Dendrite
the branched projections of a neuron that act to conduct the electrochemical stimulation received from other neural cells to the cell body, or soma, of the neuron from which the dendrites project.
Soma
cell body; the bulbous end of a neuron, containing the cell nucleus
Axon
long, slender projection of a nerve cell, or neuron, that typically conducts electrical impulses away from the neuron’s cell body
Morphological differences between axons and dendrites
dendrites often taper while axons usually maintain a constant radius
Functional differences between axons and dendrites.
dendrites usually receive signals while axons usually transmit them
Size difference between axon and dendrite
dendrites are restricted to a small region around the cell body while axons can be much longer
Synapse
structure that permits a neuron to pass an electrical or chemical signal to another cell
Chemical synapse
In a chemical synapse, the presynaptic neuron releases a chemical called a neurotransmitter that binds to receptors located in the postsynaptic cell, usually embedded in the plasma membrane.
Electrical synapse
In an electrical synapse, the presynaptic and postsynaptic cell membranes are connected by special channels called gap junctions that are capable of passing electric current, causing voltage changes in the presynaptic cell to induce voltage changes in the postsynaptic cell.
Neurotransmitter
Neurotransmitters are endogenous chemicals that transmit signals from a neuron to a target cell across a synapse.
3-Step Neurotransmitter Process
Neurotransmitters are packaged into synaptic vesicles clustered beneath the membrane in the axon terminal, on the presynaptic side of a synapse. Following an action potential, they are released into and diffuse across the synaptic cleft, where they bind to specific receptors in the membrane on the postsynaptic side of the synapse.
Action potential
action potential is a short-lasting event in which the electrical membrane potential of a cell rapidly rises and falls, following a consistent trajectory
stores various neurotransmitters that are released at the synapse.
Synaptic vesicle
a temporary depolarization of postsynaptic membrane potential caused by the flow of positively charged ions into the postsynaptic cell as a result of opening of ligand-sensitive channels
excitatory postsynaptic potential
excitatory postsynaptic potential
temporary depolarization of postsynaptic membrane potential caused by the flow of positively charged ions into the postsynaptic cell as a result of opening of ligand-sensitive channels
All or none principle
The amplitude of an action potential is independent of the amount of current that produced it.
Axon hillock
The axon hillock is a specialized part of the cell body (or soma) of a neuron that connects to the axon. As a result, the axon hillock is the last site in the soma where membrane potentials propagated from synaptic inputs are summated before being transmitted to the axon.
Interneuron, Local circuit neuron
a neuron that forms a connection between other neurons
Function of myelin
The fat helps to insulate the axons from electrically charged atoms and ions. The main purpose of a myelin layer (or sheath) is to increase the speed at which impulses propagate along the myelinated fiber. Myelin helps prevent the electrical current from leaving the axon.
Main types of neuroglia (3)
Astrocytes, oligodendrocytes, microglial cells
Astrocytes (Shape, Prevalence, Major functions)
characteristic star-shaped glial cells in the brain and spinal cord. They are the most abundant cell of the human brain. They perform many functions, including biochemical support of endothelial cells that form the blood–brain barrier, provision of nutrients to the nervous tissue, maintenance of extracellular ion balance, and a role in the repair and scarring process of the brain and spinal cord following traumatic injuries.