CHAPTER11 Flashcards
human microbiome
collection of microorganisms living on and inside the human body
normal, resident microbiota
mo that can permanently colonize the body w/o causing disease under normal conditions
transient microbiota
mo that temporarily live in or on the body but do not permanently stay
infection
invasion and multiplication of mo within the bodyd
disease
the condition caused by mo that disrupt normal body functions
microbial antagonism
the competitive interaction between normal microbiota and pathogens that prevents infections
pathogenicity
the ability of a mo to cause a disease
true pathogens
organisms like the cold virus, influenza and malaria which can cause disease in healthy individuals
opportunistic pathogens
mo that do not cause disease in healthy individuals but can cuase disease when the host’s defenses are compromised
virulence
the degree of pathogenicity of an organism, including factors like virulence factors
polymicrobial infections
infections caused by more than one microorganism, such as influenza and pneumococcal bacteria causing pneumonia
portals of entry and exit
the pathways by which pathogens can exit and enter the body
exotoxins
toxic proteins that can cause damage to host cells
endotoxins
toxins that trigger inflammatory responses, esp in GN bacteria
phases of infection
incubation, prodromal, acute, convalescence and latency
carriers
individuals who harbor pathogens w/o showing symptoms but can transmit them
three ways mo can damage hosts
direct damage
inducing an immune response
formation of biofilms
Hemolysins
exotoxins that lyse RBCs, releasing hemoglobin, which can lead to anemia or contribute to spread of infection
S/S of inflammation
Redness
Head
Swelling
Pain
Loss of function
leukocytosis
an increase in the number of WBCs, often a response to infection
leukopenia
a decrease in the number of WBCs which can result from certain infections or immune system disorders
septicemia
presence of bacteria or their toxins in the blood, leading to a systemic inflammatory response. can progress to septic shock
bacteremia/viremia
b- presence of bacteria in bloodstream
v- virus in blood stream
asymptomatic
disease or infection that does not produce any symptoms