Checkpoint 1 Flashcards
(35 cards)
Dominant cell type in a wound after 3 to 5 days
Macrophages
Deposition of granulation tissue is an event of which phase of the wound healing process
Proliferative (day 3 - weeks)
Days after a myocardial infarction (MI) when the tissue is more prone to spontaneous rupture of a wall or a papillary muscle rupture
3 to 5 days
*Tissue is most fragile due to predominancy of granulation tissue
Function of an Institutional (Ethics) Review Board
To approve, monitor, and review biomedical and behavioral research involving humans
(eg, institutional enrollment in a new medication study involving hepatitis C patients)
During which of the stages of the bacterial growth curve is spore production at its maximum
Stationary phase
*Growth ceases due to depletion of nutrients or accumulation of toxins
Branchial cysts are the result of incomplete obliteration of which embryonic structure(s)
2nd, 3rd, or 4th branchial clefts
Anatomic location of branchial cysts
Laterally placed, along the anterior border of the sternocleidomastoid muscle
Benign reaction to tumor invasion characterized by excessive fibrous formation that may confer the property of chemorresistance to a tumor
Desmoplasia
Cardiac defect present in 25% of patients with cri-du-chat syndrome
Ventricular septal defect
Characteristic age of onset of autosomal recessive polycystic kidney disease
Childhood
Main macroscopic difference between autosomal recessive and dominant polycystic kidney diseases
In the recessive form, the kidney’s capsule is not distorted
Defective gene in autosomal recessive polycystic kidney disease
PKHD1, that codes for fibrocystin
Organs involved in autosomal recessive polycystic kidney disease
Kidney and liver
Associated mutation in Wilms tumor (also known as nephroblastoma)
WT1 gene mutation or deletion, located on the short arm of chromosome 11
Most common childhood tumor
Wilms tumor (nephroblastoma)
Components of the WAGR syndrome mutation (*NOT DELETION)
- Wilms tumor
- Aniridia
- Genito-urinary malformations
- Retardation (mental)
Signs, symptoms, and characteristics of Sturge-Weber syndrome
- Sporadic
- Stain (port-wine) in CN V1 and 2 distribution
- Tram-track calcifications
- Unilateral
- Retardation
- Glaucoma
- GNAQ gene
- Epilepsy
CNS malformations seen in Arnold-Chiari syndromes
Spinal cord malformations with downward displacement of the cerebelar tonsils and vermis into the foramen magnum
Conditions associated to Arnold-Chiari syndromes
- Hydrocephaly
- Myelomeningocele
- Syringomyelia
Characteristic CNS malformation seen in Dandy-Walker syndrome
Large, distended fourth ventricle with a hypoplastic (or absent) cerebellum
Organ targets of Diphtheria toxin
- Heart
- Nerves
- Epithelium
Areas of the body drained by the superficial inguinal lymph nodes
- Anal canal (below pectinate line)
- Skin below umbilicus (except popliteal area)
- Scrotum and penis
- Vulva
Areas of the body drained by the para-aortic lymph nodes
- Testes
- Ovaries
- Kidneys
- Uterus
Generation 1 antihistaminics
- Diphenhydramine
- Chlorpheniramine
- Hydroxyzine
