Chem-Proteins Flashcards
(11 cards)
1
Q
causes of hypoproteinimia
low TP
A
- anemia
- acute blood loss
- inflammation
- PLE
- overzealous IV fluids
- will occur with hypoalbuminemia or hypoglobulinemia
2
Q
causes of hyperproteinemia
high TP
A
- dehydration
- can occur in conjunction with erythrocytosis
- can occur due to hyperglobulinemia or hyperalbuminemia
3
Q
main mechanisms of hypERalbuminemia
A
- physiologic - hemoconcentration (most common)
- increased production
4
Q
causes of increased albumin production?
A
- hepatocellular carcinoma
- exogenous corticosteroids
5
Q
main mechanisms of hypoalbuminemia?
A
- iatrogenic (IVF diuresis)
- decreased production
- increased loss
6
Q
hypoalbuminemia caused by decreased production
A
- malnutrition, malabsorption, maldigestion
- hepatic insufficiency or failure
- inflammation (negative acute phase protein)
7
Q
hypoalbuminemia caused by increased loss
A
- Protein-losing enteropathies or nephropathies
- severe hemorrhage
- blood loss
- exudative dermatopathies
- third space loss
8
Q
causes of hypERglobulinemia?
A
- inflammation (positive acute phase protein)
- neoplasia (rare) - multiple myeloma, lymphoma, leukemia
- infection
- chronic liver dz
mechanism = always increased production
9
Q
causes of hypOglobulinemia
A
- FPT
- inherited immunodeficiencies (most are fatal)
- acute infections
9
Q
A
10
Q
A
