Chemical Carcinogens - Oncogenic Viruses Flashcards

1
Q

Aflatoxins (organ and impact)

A

Organ: Liver
Impact: Hepatocellular carcinoma

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2
Q

Vinyl chloride (organ and impact)

A

Organ: Liver
Impact: Angiosarcoma

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3
Q

CCl4 (organ and impact)

A

Organ: Liver
Impact: Centrilobular necrosis/fatty change

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4
Q

Nitrosamines (smoked foods - organ and impact)

A

Organ: Stomach
Impact: Gastric cancer

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5
Q

Cigarette smoke (organ - larynx; and impact)

A

Organ: Larynx
Impact: Squamous cell carcinoma

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6
Q

Cigarette smoke (organ - lung; and impact)

A

Organ: Lung
Impact: Squamous cell and small cell carcinoma

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7
Q

Cigarette smoke (organ - kidney; and impact)

A

Organ: Kidney
Impact: Renal cell carcinoma

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8
Q

Cigarette smoke (organ - bladder; and impact)

A

Organ: Bladder
Impact: Transitional cell carcinoma

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9
Q

Asbestos (organ and impact)

A

Organ: Lung
Impact: Mesothelioma and bronchogenic carcinoma

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10
Q

Arsenic (organ - skin; and impact)

A

Organ: Skin
Impact: Squamous cell carcinoma

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11
Q

Arsenic (organ - liver; and impact)

A

Organ: Liver
Impact: Angiosarcoma

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12
Q

Naphthalene (aniline) dyes - organ and impact

A

Organ: Bladder
Impact: Transitional cell carcinoma

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13
Q

Alkylating agents (organ and impact)

A

Organ: Blood
Impact: Leukemia

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14
Q

Hepatocellular carincoma

A

Aflatoxins

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15
Q

Angiosarcoma of the liver

A

1 - Vinyl chloride

2 - Arsenic

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16
Q

Centrilobular necrosis and fatty changes

A

CCl4

17
Q

Gastric cancer

A

Nitrosamines

18
Q

Squamous cell carcinoma of the larynx

A

Cigarette smoke

19
Q

Squamous cell/small cell carcinoma of lung

A

Cigarette smoke

20
Q

Renal cell carcinoma

A

Cigarette smoke

21
Q

Transitional cell carcinoma of the bladder

A

1 - Cigarette smoke

2 - Naphthalene (aniline) dyes

22
Q

Mesothelioma

A

Asbestos

23
Q

Bronchogenic carcinoma

A

Asbestos

24
Q

Squamous cell carcinoma of the skin

A

Arsenic

25
Q

Leukemia

A

Alkylating agents

26
Q

EBV

A

Nasopharyngeal carcinoma, Burkitt lymphoma, CNS lymphoma in AIDS

27
Q

HHV-8

A

Kaposi sarcoma

28
Q

HBV/HCV

A

Hepatocellular carcinoma

29
Q

HTLV-1

A

Adult T-cell leukemia/lymphoma

30
Q

HPV 16, 18, 31, 33

A

Squamous cell carcinoma of vulva, vagina, anus and cervix; adenocarcinoma of cervix

31
Q

Virus associated with nasopharyngeal carcinoma

A

EBV

32
Q

Virus associated with Burkitt’s lymphoma

A

EBV

33
Q

Virus associated with CNS lymphoma in AIDS

A

EBV

34
Q

Virus associated with Kaposi sarcoma

A

HHV-8

35
Q

Virus associated with Hepatocellular carcinoma

A

HBV/HCV

36
Q

Virus associated with Adult T-cell leukemia/lymphoma

A

HTLV-1

37
Q

Virus associated with Squamous cell carcinoma of vulva, vagina, anus and cervix

A

HPV subtypes 16, 18, 31, 33