Chemical Pathology: Liver disease CPC Flashcards Preview

Rory's Year 5 pathology > Chemical Pathology: Liver disease CPC > Flashcards

Flashcards in Chemical Pathology: Liver disease CPC Deck (9)
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1
Q

Causes of raised Bilirubin?

A
  • Haemolytic Anaemia (Haemolysis)
  • Gilberts disease
  • Liver cirrhosis
  • Cholangitis
  • Hepatitis

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Pre-hepatic (eg haemolysis)

Hepatic (Repeat LFTS)

Post hepatic (Obstructive jaundice)

2
Q

Raised ungongugated bilirubin suggests?

A

Liver problem, since liver congugates Bilirubin.

3
Q

How do you differentiate between obstructive and non-obstructive causes of jaundice?

A

Urine uribinogen.

uribinogen in urine suggests non-obstructive cause of raised bilirubin.

No uribinogen suggests obstructice cause of raised bilirubin.

4
Q

In the context of jaundice, what does raised AST and raised ALT suggest?

A

Hepatic cause of jaundice

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Raised AST and raised ALT indicate liver damage

5
Q

In the context of jaundice, what does a raised Alk Phos suggest?

A

Obstructive cause of jaundice (eg gallstones)

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Not sure why really

6
Q

Spider Naevi

Gynocomastea

Palmer erythema

Dupuytrens contracture

Most likely diagnosis?

A

Alcoholic hepatitis

7
Q

Signs of Portal hypertension?

A

Splenomegaly

Visible veins

Ascites (Shifting dullness)

8
Q

Patient is jaundiced and the gallbladder is palpable. What is the most likely diagnosis?

A

Pancreatic cancer

9
Q

Two causes of obstructive jaundice?

A

Gallstones

Pancreatic cancer

Decks in Rory's Year 5 pathology Class (39):