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BCOP- Joey > Chemo Regimens > Flashcards

Chemo Regimens Flashcards

1
Q

7 + 3

A

Cytarabine (7days) +

Daunorubicin OR idaurubicin OR mitoxantrone (3 days)

AML

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2
Q

ABVD

A

Doxorubicin
Bleomycin
Vinblastine
Dacarbazine

Hodgkin’s lymphoma

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3
Q

DBVE-PC

A

Doxorubicin
Bleomycin
Vincristine
Etoposide
Prednisone
Cyclophosphamide

Childhood Hodgkin’s lymphoma

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4
Q

AC

A

Doxorubicin
Cyclophosphamide

Breast cancer

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5
Q

ACVBP-R

A

Doxorubicin
Cyclophosphamide
Vindesine
Bleomycin
Prednisone
Rituximab

DLBCL

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6
Q

ADOC

A

Doxorubicin
Cisplatin
Vincristine
Cyclophosphamide

Thyoma

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7
Q

BACOD

A

Bleomycin
Doxorubicin
Cyclophosphamide
Vincristine
Dexamethasone

DLBCL

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8
Q

BEACOPP

A

Bleomycin
Etoposide
Doxorubicin
Cyclophosphamide
Vincristine
Procarbazine
Prednisone

Hodgkin’s lymphoma

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9
Q

BEP

A

Bleomycin
Etoposide
Cisplatin

Ovarian and testicular germ cell tumors

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10
Q

CAF

A

Cyclophosphamide
Doxorubicin
Fluorouracil

Breast cancer

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11
Q

CAPOX

A

Capecitabine
Oxaliplatin

Colorectal cancer

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12
Q

CAV

A

Cyclophosphamide
Doxorubicin
Vincristine

Aka: VAC

Extensive stage Small cell lung cancer

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13
Q

CBV

A

Cyclophosphamide
Carmustine
Etoposide

Acute leukemia

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14
Q

CDOP

A

Cyclophosphamide
Doxorubicin (liposomal)
Vincristine
Prednisone

DLBCL

R-CDOP -add rituximab

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15
Q

CEOP-R

A

Cyclophosphamide
Etoposide
Vincristine
Prednisone
Rituximab

DLBCL

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16
Q

CEOP-R

A

Cyclophosphamide
Etoposide
Vincristine
Prednisone
Rituximab

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17
Q

CEPP

A

Cyclophosphamide
Etoposide
Procarbazine
Prednisone

Hodgkin’s lymphoma, DLBCL

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18
Q

ChlVPP-EVA

A

Chlorambucil
Vincristine
Procarbazine
Prednisone
Etoposide
Vinblastine
Doxorubicin

Hodgkin’s lymphoma

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19
Q

CHOEP

A

Cyclophosphamide
Doxorubicin
Vincristine
Etoposide
Prednisone

DLBCL

R-CHOEP - add rituximab

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20
Q

CHOP

A

Cyclophosphamide
Doxorubicin
Vincristine
Prednisone

Non-Hodgkin’s lymphoma

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21
Q

R-CHOP

A

Rituximab
Cyclophosphamide
Doxorubicin
Vincristine
Prednisone

DLBCL, mantle cell lymphoma

No need for initial g-CSF

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22
Q

ClaPD

A

Clarithromycin
Pomalidonide
Dexamethasone

Multiple myeloma

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23
Q

CMF

A

Cyclophosphamide
MTX
Fluorouracil

Breast cancer

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24
Q

CMV

A

Cisplatin
MTX
Vinblastine

Bladder carcinoma

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25
Q

CNOP

A

Cyclophosphamide
Mitoxantrone
Vincristine
Prednisone

Non-Hodgkin’s lymphoma

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26
Q

CODOX-M/IVAC

A

Cyclophosphamide
Vincristine
Doxorubicin
MTX
Ifosfamide
Etoposide (vepesid)
Cytarabine (ara-c)

Burkits lymphoma

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27
Q

COP

A

Cyclophosphamide
Vincristine
Prednisone

Non-Hodgkin’s lymphoma

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28
Q

COPP

A

Cyclophosphamide
Vincristine
Procarbazine
Prednisone

Hodgkin’s lymphoma
Non-Hodgkin’s lymphoma

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29
Q

CT

A

Cisplatin
Paclitaxel

Ovarian cancer

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30
Q

CTD

A

Cyclophosphamide
Thalidomide
Dexamethasone

Multiple myeloma

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31
Q

CVAD

A

Cyclophosphamide
Vincristine
Doxorubicin
Dexamethasone

Multiple myeloma

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32
Q

CVP

A

Cyclophosphamide
Vincristine
Prednisone

Non-Hodgkin’s lymphoma

Aka COP

R-CVP- add rituximab (follicular lymphoma)

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33
Q

CyBorD

A

Cyclophosphamide
Bortezomib
Dexamethasone

Multiple myeloma, AL anyloidosis

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34
Q

DA-EPOCH

A

Dose adjusted
Etoposide
Prednisone
Vincristine
Cyclophosphamide
Doxorubicin

Non-Hodgkin’s lymphoma

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35
Q

DA-R-EPOCH

A

Dose adjusted
Rituximab
Etoposide
Prednisone
Vincristine
Cyclophosphamide
Doxorubicin

Non-Hodgkin’s lymphoma

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36
Q

DBVE-PC

A

Doxorubicin
Bleomycin
Vincristine
Etoposide
Prednisone
Cyclophosphamide

Aka POG 9245

Hodgkin’s lymphoma

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37
Q

DCEP

A

Dexamethasone
Cyclophosphamide
Etoposide
Cisplatin

Multiple myeloma

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38
Q

DHAP

A

Dexamethasone
High dose
Cytarabine
Cisplatin

Relapsed refractory non-Hodgkin’s lymphoma

Hodgkin’s lymphoma

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39
Q

R-DHAX

A

Rituximab
Dexamethasone
High dose
Cytarabine
Oxaliplatin

Non-Hodgkin’s lymphoma

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40
Q

DICE

A

Dexamethasone
Isofosphamide
Cisplatin
Etoposide

Non-Hodgkin’s lymphoma

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41
Q

DT-PACE

A

Dexamthasone
Thalidomide
Cisplatin
Doxorubicin
Cyclophosphamide
Etoposide

Relapsed refractory multiple myeloma Multiple myeloma - salvaged chemo for aggressive MM

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42
Q

EC

A

Etoposide
Carboplatin

Extensive stage small cell lung cancer

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43
Q

ECF

A

Epirubicin
Cisplatin
Fluorouracil

Advanced stage gastric cancer

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44
Q

EOX

A

Epirubicin
Oxaliplatin
Capecitabine (xeloda)

Advanced oesophagogastric cancer

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45
Q

EP

A

Etoposide
Cisplatin

Advanced stage testicular cancer

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46
Q

ES-HAP

A

Etoposide
Methylprednisolone
High dose
Cytarabine
Cisplatin (platinol)

Relapsed refractory Hodgkin’s

Non-Hodgkin’s lymphoma

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47
Q

R-ESHAP

A

Rituximab
Etoposide
Methylprednisolone
High dose
Cytarabine
Cisplatin

Relapsed refractory Hodgkin’s

Non Hodgkin’s lymphoma

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48
Q

FAM

A

Fluorouracil
Doxorubicin
Mitomycin

Gastric and pancreatic cancer

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49
Q

FCM

A

Fludarabine
Cyclophosphamide
Mitoxantrone

CLL

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50
Q

R-FMC

A

Rituximab
Fludarabine
Mitoxantrone
Cyclophosphamide

Indolent no Hodgkin’s
Relapsedrefractory mantel cell lympho
CLL

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51
Q

FEC

A

Fluorouracil
Epirubicin
Cyclophosphamide

Metastatic breast cancer

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52
Q

FL

A

Fluorouracil
Leucovorin

Colon cancer

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53
Q

FLAG

A

Fludarabine
Cytarabine
Filgrastim

AML

54
Q

FLAG-Ida

A

Idarubicin
Fludarabine
Cytarabine
Filgrastim

Myelodysplastic syndromes
AML

55
Q

Mito-FLAG

A

Mitoxantrone
Fludarabine
Cytarabine
Granulocyte colony stimulating factor

Recurrent refractory AML

56
Q

FLAMSA

A

Fludarabine
Amsacrine
Cytarabine

Myelodysplastic syndrome, AML

57
Q

FLAMSA-BU

A

Fludarabine
Amsacrine
Cytarabine
Busulfan

Myelodysplastic syndrome, AML

58
Q

FLAMSA-MEL

A

Fludarabine
Amsacrine
Cytarabine
Melphalan

Myelodysplastic syndrome, secondary AML

59
Q

FM

A

Fludarabine
Mitoxantrone

Indolent non-Hodgkin’s lymphoma

60
Q

FMC

A

Fludarabine
Cyclophosphamide
Mitoxantrone

CLL

61
Q

R-FMC

A

Rituximab
Fludarabine
Mitoxantrone
Cyclophosphamide

Indolent non-Hodgkin’s lymphoma, refractory mantle cell lymphoma, CLL

62
Q

FMR

A

Fludarabine
Mitoxantrone
Rituximab

Indolent non-Hodgkin’s lymphoma

63
Q

FN-D

A

Fludarabine
Novantrone (mitoxantrone)
Dexamethasone

Indolent non-Hodgkin’s

64
Q

FOLFIRI

A

Leucovorin (folinic acid)
5-FU
Irinotecan

Metastatic colorectal cancer

65
Q

FOLFIRINOX

A

Leucovorin (folinic acid)
5-FU
Irinotecan
Oxaliplatin

Pancreatic cancer

66
Q

FOLFOX

A

Leucovorin (folinic acid)
5-FU
Oxaliplatin

Colorectal cancer

5FU Given as bolus AND infusion

Continuous infusion given in take home caset

Caution if cirrhosis

67
Q

GemOx

A

Gemcitabine
Oxaliplatin

Biliary adenocarcinoma, pancreatic cancer, hepa to cellular cancer, testicular cancer

68
Q

R-GemOx

A

Rituximab
Gemcitabine
Oxaliplatin

Refractory relapsing mantle cell lymphoma

69
Q

GVD

A

Gemcitabine
Vinorelbine
Doxorubicin

Hodgkin’s lymphoma

70
Q

Hyper-CVAD

A

Cyclophosphamide
Vincristine
Doxorubicin
Dexamethasone
+HD MTX and Cytarabine

Multiple myeloma, DLBCL, burkitts lymphoma

Note: there is vincristine on day 11, but you CAN still give G-CSF bc vincrtistine is NOT myelosuppressive!

Can add rituximab for DLBCL

71
Q

IAC

A

Idarubicin
Cytarabine
Cladrabine

AML

72
Q

IA

A

Idarubicin
Cytarabine

AML, acute promyelocytic leukemia

73
Q

ICE

A

Ifosfamide
Carboplatin
Etoposide

Relapsed refractory non-Hodgkin’s, Hodgkin’s

74
Q

R-ICE

A

Rituximab
Ifosfamide
Carboplatin
Etoposide

Relapsed refractory non-Hodgkin’s

75
Q

IDA-FLAG

A

Idarubicin
Fludarabine
Cytarabine
Filgrastim

Poor risk Myelodysplastic syndromes, AML

76
Q

IFL

A

Irinotecan
5-FU
Leucovorin

Advanced stage colorectal cancer

77
Q

LR- CHOP-21

A

Lenolidomide (revlimid)
Rituximab
Cyclophosphamide
Doxorubicin
Vincristine
Prednisone

Relapsed or refractory DLBCL

78
Q

M-BACOD

A

MTX
Bleomycin
Doxorubicin
Cyclophosphamide
Vincristine
Dexamethasone

Non-Hodgkin’s lymphoma

79
Q

MACOP-B

A

MTX
Doxorubicin
Cyclophosphamide
Vincristine
Prednisone
Bleomycin

Non-Hodgkin’s lymphoma

80
Q

MCOP

A

Cyclophosphamide
Novantrone (mitoxantrone)
Vincristine
Prednisone

Aka- CNOP

Non-Hodgkin’s lymphoma

81
Q

MINE

A

Mesna
Ifosfamide
Mitoxantrone (novantrone)
Etoposide

Relapsed refractory Hodgkin’s, non-Hodgkin’s lymphoma

82
Q

R-MINE

A

Rituximab
Mesna
Ifosfamide
Mitoxantrone (novantrone)
Etoposide

Relapsed or refractory Hodgkin’s lymphoma, non-Hodgkin’s lymphoma

83
Q

Mini-BEAM

A

Carmustine (BCNU)
Etoposide
Cytarabine
Melphalan

Relapsed or refractory Hodgkin’s lymphoma

84
Q

MOPP

A

Mechlorethamine
Vincristine
Procarbazine
Prednisone

Stage 1-4 Hodgkin’s lymphoma

85
Q

MVAC

A

MTX
Vinblastine
Doxorubicin
Cisplatin

Advanced stage bladder cancer

86
Q

PCV

A

Procarbazine
Lomustine (CCNU)
Vincristine

Low grade adult oligodendroglial tumors

87
Q

ProMACE-cytaBOM

A

Prednisone
MTX
Doxorubicin
Cyclophosphamide
Etoposide
Cytarabine
Bleomycin
Vincristine
MTX

Aggressive non-Hodgkin’s lymphoma

88
Q

ProMACE-MOPP

A

Prednisone
MTX
Doxorubicin
Cyclophosphamide
Etoposide
Mustargen (mechlorethamine)
Vincristine
Procarbazine
Prednisone

DLBCL, primary CNS lymphoma

89
Q

R-CHMP

A

Rituximab
Cyclophosphamide
Doxorubicin
Vincristine (liposomal- Marqibo)
Prednisone

Aggressive non-Hodgkin’s lymphoma

90
Q

RDHAOx

A

Rituximab
Dexamethasone
High dose
Cytarabine
Oxaliplatin

Follicular non-Hodgkin’s lymphoma

91
Q

R-GCVP

A

Rituximab
Gemcitabine
Cyclophosphamide
Vincristine
Prednisone

DLBCL

92
Q

R-HCVAD

A

Rituximab
Cyclophosphamide
Vincristine
Doxorubicin
Dexamethasone

Mantle cell lymphoma

93
Q

R-MA

A

Rituximab
MTX
Cytarabine

Mantle cell lymphoma

94
Q

R2-CHOP

A

Lenalidomide (revlimid)
Rituximab
Cyclophosphamide
Doxorubicin
Vincristine
Prednisone

AKA LR-CHOP-21

Relapsed or refractory DLBCL

95
Q

RCD

A

Rituximab
Cyclophosphamide
Dexamethasone

Indolent non-Hodgkin’s lymphoma, CLL

96
Q

RdC

A

Revlimid
Dexamethasone
Cyclophosphamide

AL amyloidosis

97
Q

RVD

A

Revlimid
Velcade
Dexamethasone

Multiple myeloma

98
Q

SMILE

A

Steroid (dexamethasone)
MTX
Ifosfamide
L-asparginase
Etoposide

NK/T-cell lymphoma

99
Q

Stanford V

A

Mechlorethamine
Doxorubicin
Vinblastine
Vincristine
Bleomycin
Etoposide
Prednisone

Hodgkin’s lymphoma

100
Q

TAC

A

Docetaxel (taxotere)
Doxorubicin
Cyclophosphamide

Breast cancer

101
Q

TAP

A

Paclitaxel
Anthracycline
Cisplatin

Endometrial cancer

102
Q

TC

A

Docetaxel (taxotere)
Cyclophosphamide

Breast cancer

103
Q

TCH

A

Docetaxel (taxotere)
Carboplatin
Traztuzumab (herceptin)

Her-2/neu-positive breast cancer

104
Q

Thal/dex

A

Thalidomide
Dexamethasone

Multiple myeloma

105
Q

TIP

A

Paclitaxel (taxol)
Ifosfamide
Cisplatin (platinol)

Advanced testicular cancer, squamous cell head and neck cancer

106
Q

VAD

A

Vincristine
Doxorubicin
Dexamethasone

Multiple myeloma

107
Q

VAPEC-B

A

Vincristine
Doxorubicin
Prednisolone
Etoposide
Cyclophosphamide
Bleomycin

Non-Hodgkin’s lymphoma

108
Q

VCAP-AMP-VECP

A

Vincristine
Cyclophosphamide
Doxorubicin
Prednisone
Doxorubicin
Ranimustine (MCNU)
Prednisone
Vindestine
Etoposide
Carboplatin
Prednisone

Human T-lymphotropic virus type 1 associated adult T-cell lymphoma (ATLL)

109
Q

VeIP

A

Vinblastine
Ifosfamide
Cisplatin

Germ cell ovarian and testicular cancer

110
Q

VIP

A

VePesid (etoposide)
Ifosfamide
Cisplatin (platinol)

Germ cell gonadal cancers, thymoma

111
Q

VR-CHOP

A

Velcade
Rituximab
Cyclophosphamide
Doxorubicin
Vincristine
Prednisone

DLBCL, mantle cell lymphoma

112
Q

VTD-PACE

A

Velcade
Thalidomide
Dexamethasone
Cisplatin (platinum)
Doxorubicin
Cyclophosphamide
Etoposide

Multiple myeloma - salvaged chemo for aggressive MM

113
Q

Ependymomes

A

Surgery—>RT

Chemo usually not used

114
Q

VR-CAP

A

Bortezomib+ rituximab+ cyclophosphamide + doxorubicin + prednisone

Mantle cell lymphoma

115
Q

R-CEPP

A

Rituximab, cyclophos, etoposide, Procarbazine, prednisone

DLBCL

116
Q

R-GDP

A

Rituximab + Gemcitabine + dex + cisplatin

R/R DLBCL transplant eligible

117
Q

FCR

A

Fludarabine, cyclophosphamide, rituximab

CLL

118
Q

G-CHOP

A

Obinutuzumab-CHOP

FL

119
Q

VR-CAP

A

Bortezomib + rituximab + cyclophosphamide+dox + pred

Mantle cell lymphoma (less aggressive)

120
Q

STRIDE

A

Single dose Tremelimumab regular interval Durvalumab

Tremelimumab 300 mg x1 + Durvalumab 1500 mg q4 weeks

121
Q

mFOLFOX6

A

400 mg/m2 leucovorin on day 1 over 2 hrs with Oxaliplatin 85 mg/m2 followed by 400 mg/m2 5FU bolus followed by 2400 mg mg/m2 5FU continuous infusion over 46 hours

every 14 days

122
Q

Rituximab rapid infusion- if patient did NOT have a grade 3-4 infusion rxn with first cycle

A

Over 90 mins
-20% over 30 mins and 80% over the remaining 60 mins
-subsequent cycles can be given at that rate
Dont use if lymphocyte count >5k or in pts with clinically significant CV dx

FL or DLBCL with steroid containing regimen

123
Q

Nordic regimen

A

R-maxi-CHOP alternating with R-high-dose Cytarabine

R-Maxi CHOP: rituximab, cyclophosphamide, vincristine, prednisone

Mantle cell lymphoma

124
Q

A + AVD

A

Brentuximab vedotin + dox + Vinblastine + Dacarbazine

HL- give with G-CSF- not for pts >60 or with baseline neuropathy
-more costly
-more myelosuppression

125
Q

HD-18 and AHL-2011

A

PET adapted BEACOPP

126
Q

R-DHAP

A

Rituximab, dex, high dose Cytarabine, cisplatin

127
Q

DCEP

A

Dex/cyclo/etop/cisplatin

Aggressive forms if multiple myeloma

128
Q

DCEP

A

Dex/cyclo/etop/cisplatin

Aggressive forms if multiple myeloma

129
Q

DeAngelis regimen

A

R-PCV q14 days

Needs filgrastim NOT peg-filgrastim

130
Q

LyMA

A

R-DHA + platinum followed by R-CHOP in incomplete response

MCL

131
Q

Triangle

A

Alternating R-CHOP + covalent BTKI/R-DHA + platinum

MCL

132
Q

RBAC500

A

Rituxan + bendamustine + Cytarabine

MCL

BCOP- Joey (10 decks)

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