Chemotherapy VI Principles of Cancer Therapy Flashcards Preview

► Med - Pharmacology > Chemotherapy VI Principles of Cancer Therapy > Flashcards

Flashcards in Chemotherapy VI Principles of Cancer Therapy Deck (8)
Loading flashcards...
1
Q

What is the most important factor for the prognosis and treatment of cancer?

A

Stage of the cancer

2
Q

What is one of the most successful methods for curing cancer?

A

Surgery - localized disease finds the highest success with good surgical removal

3
Q

What chemotherapy agent is contraindicated in those with renal failure?

A

Cisplatin

4
Q

What chemotherapy agent is contraindicated in those with CHF?

A

Doxorubicin

5
Q

What is adjuvant chemotherapy?

A

Therapy for patients who have had cancer removed but are at risk of recurrence

6
Q

Neoadjuvant Chemotherapy

A

Reduces tumor cells prior to surgery

7
Q

Log Kill Hypothesis

A

The killing of cancer cells by the chemotherapy drugs follows first order kinetics. The same fraction of cancer cells is killed with each administration of chemotherapy.

8
Q

Why is combination chemotherapy better?

A

Combinations provide maximal cell kill within the range of toxicity tolerated by the host for each drug - log cell kill is increased

Decks in ► Med - Pharmacology Class (74):