Cholinolytics Flashcards Preview

Pharmacology > Cholinolytics > Flashcards

Flashcards in Cholinolytics Deck (10):
1

Tropicamide

Muscarinic antagonist, affects eye

Produces mydriasis and cycloplegia (inhibits ciliary muscle)

2

Benztropine

Muscarinic antagonist, affects CNS

Treats Parkinson disease

3

Scopolamine

Muscarinic antagonist, affects CNS

Treats motion sickness

4

Ipratropium, tiotropium

Muscarinic antagonist; affects respiratory system

Treats COPD, asthma

5

Oxybutynin, darifenacin, solifenacin

Muscarinic antagonist; affects GU system

Reduces urgency in mild cystitis and reduces bladder spasms

6

Glycopyrrolate

Muscarinic antagonist; affects GI and respiratory systems

Reduces airway secretions; helps to prevent drooling and peptic ulcer development

7

Symptoms of atropine overdose

Hot as a hare (decreased sweating)
Dry as a bone (decreased secretions)
Red as a beet
Blind as a bat (cycloplegia - loss of accommodation)
Mad as a hatter (disorientation)

8

Botulinum toxin

Blocks the release of ACh from presynaptic terminals

9

Curare

Competes wiht ACh for receptors on the motor end plate. Decreases size of end plate potential. Max doses can produce paralysis of respiratory muscles.

10

Hemicholinium

Blocks reuptake of choline inot presynaptic terminal --> depletes ACh stores from presynaptic terminal.