Chronic pain management Flashcards

(38 cards)

1
Q

What is acute pain, subacute/post-acute, chronic

A

Time limited (up to 7 days after an injury), Up to 6-12 weeks following a severe injury and/or major surgery, pain that last beyond normal expected time of tissue injury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the most common type of chronic pain

A

Back pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

T/F: Chronic pain and mental health are usually tied together

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the causes of chronic pain

A

nociceptive, neuropathic (nerve damage or abnormal functioning), mixed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

T/F: SSRIs such as escitalopram are apporved for neuropathic pain

A

False: SNRI, duloxetine, is approved for neuropathic pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The analgesic action of antidepressants occurs under what conditions

A

Even if patient is not clinically depressed, sooner and at lower doses than doses required to treat depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the first line agents for Neuropathic pain

A

Secondary amine tricyclic antidepressants (despiramine and nortriptyline), Duloxetine, gabapentin, pregablin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the second line of neuropathic pain, concern, other

A

Tramadol, increased abuse potential for chronic pain and a risk factor for long-term opiod use, licdocaine patch

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the third line, caveat

A

Immediate release opiod, effective in the short-term while titrating antidepressants and/or anticonvulsants to optimal dosages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

T/F: For treating pain start low and go slow when titrating

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

If partial pain relieft is present and side effects are tolerable what should be done, problematic, pain relief is INADEQUATE

A

Increase the dose, add a first line agent with a DIFFERENT mechanism of action, adding or switching to a first line agent with a different mechanism of action

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the symptom duration of acute back pain, subacute, chronic

A

Greater than 4 weeks, 4 to 12 weeks, greater than 12 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What physiological changes usually causes acute or subacute back pain

A

Release of inflammatory mediators, muscle spasm in surrounding tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the first line treatment of acute or subacute lower back pain, second line

A

Remain active and education/ application of heat, NSAID, spinal manipulation and acupuncture

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are limited use treatment for select patients only

A

Exercise therapy, skeletal muscle relaxants (acute LBP only), opiods (CAUTION)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What treatment is not recommended for LBP, insufficient evidence

A

Acetaminophen, SNRI and gabapentinoids

17
Q

What is the MOA of anitspasticity agents, what are they

A

Act directly on skeletal muscle or in spinal cord to improve muscle hyertonicity and involuntary spasms/ Baclofen and Dantrolene

18
Q

What are the antispasomadic agents

A

Cyclobenazaprine, carisoprodol, metaxalone, methocarbamol

19
Q

What drugs are antispasmodic and antispasticity

A

Diazepam and Tizanidine

20
Q

T/F: Evidence supports a modest benefit of skeletal muscle relaxants for short-term (less than one week) for treatment of acute and is associated with faster functional recovery in LBP

A

False: Evidence dose support a modest benefit of skeletal muscle relaxants for short term for treatment of acute LBP BUT IS NOT associated with faster functional recovery/ NO STUDIES SUPPORT LONG TERM USE IF SKELETAL MUSCLE RELAXANTS

21
Q

What is the first-line treatment for chronic LBP

A

Remain active, exercise, education that includes coping with a long term health problem, cognitive behavioral therapy

22
Q

What is the first line treatment or adjunctive option for chornic LBP

A

Spinal manipulation, massage, acupuncture, yoga, stress reduction, rehab, NSAIDS, SNRI (small at best), Tramadol (kinda)

23
Q

What is not recommended for LBP, insufficient evidence

A

Acetaminophen/ application of heat and skeletal muscle relaxants

24
Q

When would gabapentionids be used in chronic LBP

A

Painful conditions with nerve pathology (sciatica, failed back surgery syndrome)

25
What are NSIADS first line for
Osteoarthritis, rheumatoid arthritis, back/neck/shoulder pain, inflammatory pain
26
What are the three types of side ffects for NSAIDs
Gastrointestinal (Hearburn, GI bleeding), Cardiovascular (MI and stroke, heart failure), Renal (AKI)
27
`What patients should NSAIDs be avoided in
Recent myocardial infarction, unstable angina, poorly compensated heart failure, CKD (3 or worse), Volume depleted
28
What disease states are associated with opiod-tolerant patingts recieving agents, which agents
Cancer pain and chronic upain unresponsive to nonopiod treatments. transdermal fentanyl patch and methadone
29
What is the indication for trnasdermal fentanyl patch
Opioid-tolerant patients with pain severe enough to require daily, around the clock, long term opioid treatment
30
Where and how is the fentanyl patch applied
Chest, back, upper arm or flank/ press patch firmly in place for about 30 seconds
31
What are the kinetics of the fentanyl patch, mininum and maximum effect, steady state
Simple diffusion with delayed onset and offset of effect 12 hours. 24 hours, 3 to 6 days
32
The patient should continue oral opioid for 12-24 hours after
True
33
After the patch is removed how long does it take to for plasma levels to fall by 50%
24 hours (must monitor for a day if oversedation/respiratory depression is seen)
34
What is patient education for fentanyl patches
DO NOT CUT patch or use altered patch, avoid exposing application site to direct heat, remove old patch once new patch is placed
35
What metabolizes methadone, adverse effects
CYP 3A4 and CYP2B6, QT prolongation
36
What are the risk factors of abusing opiods
Family history of substance abuse, personal history of substance abuse, age between 16- 45 years, psycholoigcal disease, history of preadolescent sexual abuse
37
The CDC guideline for prescribin poiods for chronic pain dose not include which patients
Active cancer treatment, acutesickle cell pain crisis, acute pain after surgery
38
T/F: Patients should be tapered off opiods in order to lessen withdrawl symptoms
True