CIN and SCCA

Question 1

What key to deacribe ocular surface lesion ?

Answer 1

Size
Involvement
Border
Pigmented
Consistency
Fixed
Vascularity

Question 2

What is the pre-invasive neoplasia ?

Answer 2

Corneal and Conjunctival intraepithelial neoplasia

Question 3

What is the invasive OSSN ?

Answer 3

Squamous cell carcinoma
muco epidermoid carcinoma

Question 4

Risk factor For develop OSSN ?

Answer 4

UV
Prior skin cancer
Older
Male sex
Smoking
HPV or HIV

Question 5

What is definition of squamous dysplasia ?

Answer 5

Invade only epithelium

Question 6

What is the definition of Squamous cwrcinoma in situ ?

Answer 6

Invasive entire epithelial layer

Question 7

Name 3 principal form of CIN

Answer 7

1.Leukoplakia
2.Gelatimous
3.Papilliform

Question 8

Clinical presentation of CIN ?

Answer 8

Slow growing
Feeder Vessel
Corneal involvement
- Translucent c mildly elevated gray epithelial
- Fombriated Margin

Question 9

Invasive OSSN characteristic ?

Answer 9

Involve beyond basement membrane into stroma

Question 10

Clinical presentation of invasive OSSN ?

Answer 10

Plaque like and gelatinous papilliform
Broad base along limbus
Engorged conjunc vessel = Malignancy

Question 11

Two variants of SCC ?

Answer 11

Mucoepidermoid
Spindle cell

Question 12

Describe Pathology CIN 1 2 3

Answer 12

Divide by epithelia thickness invasion
CIN1 = 1/3 epithelial thickness
2 = 1/3 - 2/3 thickness
3 = 2/3 Of thickness

While SCC is beyond basement membrane

Question 13

What is gold standard for diagnosis of CIN ?

Answer 13

Incisional and Excisional

Question 14

How to manage OSSN ?

Answer 14

1.Surgery
2.Chemo

Question 15

When to concern of malignancy ?

Answer 15

1.Broad base
2.Pigmentation
3.Feeder Vessel
4.Fixate

Question 16

What is the free amrgin for resection ?

Answer 16

2-4 mm

Question 17

Topical chemotherapy naming ?

Answer 17

IFN a 2
5 FU
MMC

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