Corneal Ulcer

Question 1

Definition of corneal ulcer ?

Answer 1

Corneal epithelial defect associated with stromal infiltration commonly infectious process

Question 2

Etiology of corneal ulcer ?

Answer 2

Bacterial - Common in CL : Pseudo , S Aureus , S pneumo
Virus - HSV , VZV
Fungus - Fusarium , Aspergillus , Candida
Protozoa - Acanthamoeba

Question 3

Etiology that is not infection process ?

Answer 3

NK
EK
Autoimmune
Chemical injury

Question 4

What is Clinical presentation of corneal ulcer ?

Answer 4

Eye pain
redness
Tearing
Photophobia
FB sensation
VA drop

Question 5

Sign of Corneal ulcer ?

Answer 5

Signs

Corneal epithelial defect with underlying stromal infiltrate

Hypopyon (often in bacterial/fungal)

Edema, Descemet’s folds

Ciliary injection

Satellite lesions (fungal)

Dendritic lesions (viral)

Question 6

Diagnosis ?

Answer 6

Corneal Scraping

Question 7

Treatment strategy ?

Answer 7

• Bacterial infection
• Empirical > F.Cefazolin
• Moxifloxacin
  -Fungal Ulcer
• Natamycin or voriconazole
  -Viral
• antiviral Acyclovir , Ganciclovir
  -Adjunctive
• Tears , Cycloplegic

Question 8

Surgical Indications ?

Answer 8

• Perforate + prone to perforate ( ex thinning )