Circulation of the brain Flashcards

1
Q

Brain blood supply

A

2 vertebral arteries
2 internal carotid artieries

ensures continuous supply of nutrients
removal of waste

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2
Q

internal carotid

A

in front of neck and divides to form middle and anterior cerebral arteries

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3
Q

ACA

A

2 anterior cerebral arteries join via the anterior communication artery forming the front section of circle of willis

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4
Q

Vertebral

A

2 vertabral arteries pass uo through the formaina in transverse process of Cx vertabrae and join infront of the brainstem at the basilar artery

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5
Q

Upper brain stem

A

basilar artery divides into 2 posterior cerebral arteries that connect to back of circle of willis by 2 small posterior communicating arteries

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6
Q

Circle of willis

A

occlusion of one internal carotid artery may not result in stroke because brain is protected from bilateral carotid occlusion through basilar supply

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7
Q

Middle cerebral artery

A
Most of the outer surface
Sensorimotor cortex
Basal ganglia
Internal capsule
Broca’s area (on left)
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8
Q

Anterior cerebral artery

A

Frontal lobe

Medial part of sensorimotor cortex

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9
Q

Posterior cerebral artery

A

Occipital lobe
Medial aspect of temporal lobe
Thalamus

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10
Q

Basilar artery

A

All of the brainstem
Cerebellum
Nuclei of cranial nerves

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11
Q

Disruption to blood supply

A

loss of consciousness within seconds

irreversible damage in minutes

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12
Q

Autoregulation

A

mean arterial bp of 60-150mmHg

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13
Q

BP

A

constriction or dilation of arterioles in brain

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14
Q

increase in CO2

A

dilation of arterioles in brain

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15
Q

decrease in O2

A

constriction of arterioles in brain

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16
Q

Causes of Autoregulation faliure

A
CNS disease:
Trauma
Acute stroke
Tumours
Inflammation
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17
Q

Stroke/CVA

A

brain attack
A stroke, also known as a cerebrovascular accident (CVA), is the rapid loss of brain function(s) due to disturbance in the blood supply to the brain. This can be due to ischemia (lack of blood flow) caused by blockage (thrombosis, arterial embolism), or a haemorrhage (leakage of blood).

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18
Q

Classification

A

Haemorrhagic stroke

Ischaemia stroke

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19
Q

Haemorrhagic stroke

A

bleeding from a cerebral artery

20
Q

Subarachniod haemorrhage

A

bleeding into subarachnoid space
due to rupture of congenital anerysm or traume
sudden intense headache, vomiting, neck stiffness and loss of consciousness
10% die within two hours
40% die within two weeks

21
Q

Aneurysm

A

saccular
fusiform
ruptured

treated by surgical clipping

22
Q

Intracerebral haemorhage

A
bleeding in deeper part of brain
longstanding hypertension
arterial wall weaken
micro-aneurysm develop 
rupture and bleed
sever headache and vomitting
23
Q

Ischaemic stroke

A

80% strokes due to occulsion
atherom of cerecral artery
emboli from atheromatous plaque in hear/neck vessel

Most common vessel: MCA > PCA > ACA

brainstem stroke less common but more serious

24
Q

Embolic stroke

A

completed stroke -sudden onset
transiet ischaemic attack
repeated small emboli no infraction occurs
piece of plaque can break free and clock blood supply to the brain

25
artrial fibrilation
Atrial fibrillation is irregular heartbeat,blood clots are more likely to form in your heart, increasing stroke risk
26
thrombotic stroke
``` completed stroke-overnight develops over several days transient ischaemic attack sudden to full recovery 20% risk of full CVA with 4 weeks ```
27
Bamford classification
TACS – Total anterior circulation stroke PACS – Partial anterior circulation stroke POCS– Posterior circulation stroke LACS – Lacunar stroke(deep penetrating arteries) (TAC)S=stroke (TAC)I=infarct (TAC)H=haemorrhage
28
Tramatic brain injury
injury to the brain caused by external physical force, altered state of consciousness impairment of cognitive or physical abilities disturbances of behaviour or emotional functioning temporary or permanent
29
Mechanism of injury
Penetrating injury-risk of infection Compression - inner cerebral traume Deceleration- outer cerebral injury discrete cognitive deficit Diffuse axonal injury-- poor communication between brain structures, reduces processing speed, global impairment
30
Extradural haemorrhage
bleeding into extradural space | cause by severe trauma
31
sunadural haemorrhage
bleeding in subdural space usually cause by severe trauma maybe be delayed symptons ``` headache drowsiness stupor hemiparesis coma ```
32
Secondary damage of TBI
``` raised ICP infection ischaemic changes vasospasm complication of systemic dysfunction ```
33
Transient ischaemic attack TIA
A TIA is a sign that part of the brain is not getting enough blood, and there is a risk of a more serious stroke in future
34
Hemiplegia
paralysis at one side of the body
35
Clinical features of stroke | MOTOR
Alterations in tone Low tone - flaccidity High tone – spasticity ``` Ataxia Weakness Asymmetry Loss of normal movement patterns Loss of postural adjustments loss of balance Compensations ```
36
Pattern of spasticity
``` Flexor pattern in upper limb Shoulder elevation & retraction Internal rotation & adduction Elbow flexion & pronation Wrist flexion Finger flexion ``` ``` Extensor pattern in lower limb Hip retraction Hip extension Knee extension Ankle plantarflexion & inversion ```
37
Clinical features of stroke | SENSORY
impaired cutaneous sensation stereognosis proprioceptive impairment visual problems Visual field loss Homonymous Hemianopia
38
Clinical features of stroke | SPEECH
Expressive dysphasia Damage to Brocas area Usually associated with Rt hemiplegia Loose ability to produce speech Receptive dysphasia Damage to Wernikes area in temporal lobe Lose ability to understand speech global aphasia
39
Clinical features of stroke | COGNITIVE
Perceptual Problems ``` Astereognosis Visual Agnosia Auditory Agnosia Depth perception Apraxia Anosagnosia Inattention/neglect ```
40
Agnosia
Inability to recognise objects
41
Neglet
more common with left hemiplegia patients fails to attend to stimuli from the left side poor prognosis if persists results in many functional problems
42
Clinical features of stroke
``` Disorders of emotion Dysphagia Delay / absent swallow reflex Incontinence Secondary musculoskeletal problems Balance / Gait problems Functional difficulties Social problems ```
43
Physiotherapy treatment
prevent complications, minimise impairments and to maximise function ``` Assessment Identification of problems Clinical reasoning Goal setting Objective outcomes Choice of Rx method Interdisciplinary input ```
44
Factors affecting recovery
``` Extent and nature of lesion Integrity of collateral circulation Pre-morbid status Age Capacity of Nervous System to re-organise Environment Motivation and Attitude of patient Patient participation Patient Experience Co-exisiting conditions Nutrition/Hydration Medication ```
45
Medical management
``` Treat as medical emergency MRI/CT scan Ischaemic stroke (80%)– aspirin, anticoagulants - thrombolysis SAH – surgery or endoplastic procedures SDH/EDH/ICH – treat hypertension TIA – aspirin, prevention work Other tests – Blood tests, angiography, echocardiology Other medication – osmotic agents Surgery – carotid endarterectomy ```
46
National Stroke startergy
Treat Stroke as a medical emergency Effective assessment and treatment of vascular risk factors TIAs assessed and scanned within 24hrs Suspected stroke transferred to specialist stroke unit with MDT treatment and assessment Range of services available locally to support long-term needs Opportunity to return to work