Citrate Cycle Steps

Question 1

Step 1

Answer 1

condensation of oxaloacetate and acetyl-CoA by citrate synthase to form citrate

Question 2

Step 2

Answer 2

Isomerization of citrate by aconitase to form isocitrate

Question 3

Step 3

Answer 3

Oxidative decarboxylation of isocitrate by isocitrate dehydrogenase to form alpha-ketogluterate, CO2, and NADH

Question 4

Step 4

Answer 4

Oxidative decarboxylation of alpha-ketogluterate by alpha-ketogluterate dehydrogenase to form succinyl-CoA, CO2, and NADH

Question 5

Step 5

Answer 5

conversion of succinyl-CoA to succinate by succinyl-CoA synthase in a substrate level phosphorylation reaction that generates GTP

Question 6

Step 6

Answer 6

Oxidation of succinate by succinate dehydrogenase to form fumerate

Question 7

Step 7

Answer 7

Hydration of fumerate by fumerase to form malate

Question 8

Step 8

Answer 8

Oxidation of malate by malate dehyrogenase to form oxaloacetate