Citric acid cycle Flashcards
(22 cards)
The name Citric acid cycle is after?
since it’s the first product in the cycle
The fuel in the citric acid cycle?
Acetyl CoA
the oxidizing agent in C=O IS?
NAD
the oxidizing agent in C=C is?
FAD
At what part is FAD used as oxidizing agent?
Succinate - Fumarate
What is the enzyme used in Succinate - Fumarate?
Succinate dehydrogenase
What is the readily oxidized alcohol in the cycle?
Isocitrate
The enzyme in Citrate - Isocitrate?
Aconitase
What enzyme is used in Oxidation of Isocitrate to a-ketoglutarate?
Isocitrate dehydrogenase
What enzyme is used in Oxidation of Isocitrate to a-ketoglutarate?
Isocitrate dehydrogenase
the only ketone in the cycle?
a-ketoglutarate
What is the enzyme in the conversion of a-ketoglutarate to Succinyl CoA?
ketoglutarate dehydrogenase complex
(V. B and Mg2+)
What enzyme is in the conversion of succinyl CoA to succinate/ succinyl phosphate?
Succinyl CoA synthase
What is the bond that is broken in Succinyl CoA that produces GTP and Succinate?
Thioester bond
What is the enzyme in the conversion of Succinate to Fumarate
Succinate dehydrogenase
What is the enzyme in the conversion of Fumarate to Malate?
Fumarase
Fumarase is stereospecific to _________ and catalyzes ______ to the double bond of fumarate?
Fumarase is stereospecific to (L isomer) and catalyzes (water) to the double bond of the Fumarate
What is the enzyme in the conversion of L-Malate to Oxaloacetate?
Malate dehydrogenase
What is the proper sequence of Krebs cycle?
(C)itrate
(I)socitrate
a-(k)etoglutarate
(S)uccinyl CoA
(S)uccinate
(F)umarate
L - (M)alate
(O)xaloacetate
What are the enzyme that dehydrogen?
Isocitrate dehydrogenase
a-ketoglutarate dehydrogenase
Succinyl dehydrogenase
Malate dehydrogenase
At what part of the cycle that there’s (2) GTP production?
In the phosphorylation of Succinyl CoA
How many ATP is the krebs cycle in total?
3 NADH, 1 FADH, 2 GTP = 20 ATP
