citric acid cycle regulation

Question 1

e1 catalyzed the _____ ______ and _____ step = main regulation

Answer 1

rate-limiting, committed

Question 2

PDP1 and PDP2 _____ the ______ version of E1, leading to ______ activity of the PDH complex

Answer 2

dephosphorylate the inactive, increased

Question 3

PDK1 PDK2 PDK3 PDK4 ______ the ____ version of E1, leading to ____ activity of the PDH complex

Answer 3

phosphorylate the active version, leading to decreased

Question 4

what increases PDP1 and PDP2

Answer 4

ca++, mg++, insulin

Question 5

what increases pdk1,2,3,4

Answer 5

acetyl coa and nadh

Question 6

most important anaplerotic rxn in animals

Answer 6

pyruvate carboxylase

Question 7

what is pep carboxylase activated by

Answer 7

high levels of F1,6 BP

Question 8

what do anaplerotic rxns need in animals

Answer 8

glucose/glucose

Question 9

what things can synthesize sugars from acetyl coa

Answer 9

plants and microbes

Question 10

which things cannot synthesize sugars from acetyl coa

Answer 10

animals