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PHARM 1 Self > CLASS1Drugs > Flashcards

CLASS1Drugs Flashcards

(143 cards)

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1
Q

-Cimetidine (OAT)

A

Drug metabolism inhibitor

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2
Q

-Proadifen (OCT)

A

Drug metabolism inhibitor

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3
Q

-Probenecid

A

Drug metabolism inhibitor

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4
Q
  • Ethanol
A

Drug metabolism activators

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5
Q
  • Phenobarbital
A

Drug metabolism activators

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6
Q

Bethanechol

A

Cholinergic agonist – synthetic choline ester

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7
Q

Carbachol

A

Cholinergic agonist – synthetic choline ester

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8
Q

Methacholine

A

Cholinergic agonist – synthetic choline ester

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9
Q

Pilocarpine

A

Cholinergic agonist – natural alkaloid

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10
Q

Ambenonium

A

Competitive cholinesterase inhibitor - carbamate

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11
Q

Edrophonium

A

Competitive cholinesterase inhibitor - simple alcohol with quartenary ammonium

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12
Q

Neostigmine

A

Competitive cholinesterase inhibitor – carbamate with quartenary ammonium

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13
Q

Physostigmine

A

Competitive cholinesterase inhibitor – carbamate with tertiary amine

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14
Q

Pyridostigmine

A

Competitive cholinesterase inhibitor - carbamate

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15
Q
  • Diisopropyl-fluorophosphate
A

Noncompetitive cholinesterase inhibitor – OP insecticie

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16
Q
  • Echothiopate
A

Noncompetitive cholinesterase inhibitor – OP insecticie

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17
Q
  • Carbaryl
A

Noncompetitive cholinesterase inhibitor – OP insecticie

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18
Q
  • Malathion
A

Noncompetitive cholinesterase inhibitor – OP insecticie

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19
Q
  • Parathion
A

Noncompetitive cholinesterase inhibitor – OP insecticie

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20
Q
  • Tetraethyl-pyrophosphate
A

Noncompetitive cholinesterase inhibitor – OP insecticie

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21
Q
  • Sarin
A

Noncompetitive cholinesterase inhibitor – nerve gas

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22
Q
  • Soman
A

Noncompetitive cholinesterase inhibitor – nerve gas

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23
Q

Pralidoxime

A

AchE reactivator – cholinesterase inhibitor

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24
Q

Atropine

A

Cholinergic antagonist – highly muscarinic selective (low potency at nicotinic), no M subtype selectivity – 3 amine

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25
Homatropine
Cholinergic antagonist – muscarinic selective – 3 amine
26
Scopolamine
Cholinergic antagonist – very muscarinic selective – 3 amine
27
Methscopolamine
Cholinergic antagonist – muscarinic selective – 4 ammonium
28
Trihexyphenidyl
Cholinergic antagonist – muscarinic selective – 3 amine
29
Tropicamide
Cholinergic antagonist – muscarinic selective – 3 amine
30
Cyclopentolate
Cholinergic antagonist – muscarinic selective
31
Ipratropium
Cholinergic antagonist – muscarinic selective – 4 ammonium
32
Tiotropium
Cholinergic antagonist – muscarinic selective
33
- Darifenacin
Cholinergic antagonist – M3 selective
34
- Solifenacin
Cholinergic antagonist – M3 selective
35
- Tolterodine
Cholinergic antagonist – M3 selective
36
Mecamylamine
Cholinergic antagonist – nicotinic selective – 2 amine – nondepolarizing competitive antagonists
37
Trimethaphan
Cholinergic antagonist – nicotinic selective – sulfonium- nondepolarizing competitive antagonists
38
Succinylcholine
Cholinergic antagonist – depolarizing, noncompetitive receptor agonist for ACh action
39
Curare
Cholinergic antagonist – non-depolarizing – long acting, benzylisoquinoline
40
Atracurium
Cholinergic antagonist – non-depolarizing
41
Cisatracurium
Cholinergic antagonist – non-depolarizing – intermediate length, benzylisoquinoline
42
Mivacurium
Cholinergic antagonist – non-depolarizing – short acting, benzylisoquinoline
43
Pancuronium
Cholinergic antagonist – non-depolarizing – long acting, ammonio steroid
44
Vecuronium
Cholinergic antagonist – non-depolarizing – intermediate length, ammonio steroid
45
Metaraminol
Adrenergic agonist – a1 selective (a1 >> a2)
46
Methoxamine
Adrenergic agonist – a1 selective
47
Phenylephrine
Adrenergic agonist – a1 selective (a1 = a2)
48
- a-methyldopa
Adrenergic agonist – a2 selective
49
- Clonidine
Adrenergic agonist – a2 selective
50
- Guanabenz
Adrenergic agonist – a2 selective
51
Amphetamine
Adrenergic agonist – mixed a/b,
52
Ephedrine
Adrenergic agonist – mixed a/b, NE releasing agent
53
Dipivefrin
Adrenrgic agonist – mixed a/b NE releasing agent
54
Epinephrine
Adrenergic agonist – mixed a/b – a1 = a2, B1 = B2
55
Norepinephrine
Adrenergic agonist – mixed a/b – a1 = a2, B1>>B2
56
Dobutamine
Adrenergic agonist – B1 selective
57
Isoproterenol
Adrenergic agonist – B non-selective
58
Albuterol
Adrenergic agonist – B2 selective
59
Metaproterenol
Adrenergic agonist – B2 selective
60
Terbutaline
Adrenergic agonist – B2 selective
61
Bromocriptine
Adrenergic agonist – dopamine (D2)
62
Dopamine
Adrenergic agonist – dopamine, D1 = D2
63
Doxazosin
Adrenergic antagonist – a1 selective >>>> a2
64
Prazosin
Adrenergic antagonist – a1 selective >>>> a2
65
- Tamsulosin
Adrenergic antagonist – a1 selective >>>> a2
66
- Terazosin
Adrenergic antagonist – a1 selective >>>> a2
67
Phenoxy-benzamine
Adrenergic antagonist – a non-selective a1 > a2
68
Phentolamine
Adrenergic antagonist – a non-selective a1 = a2
69
Labetalol
Adrenergic antagonist – mixed a/b – B1 = B2 > a1 > a2
70
Atenolol
Adrenergic antagonist – B1 selective >>>> B2
71
Betaxolol
Adrenergic antagonist – B1 selective >>>> B2
72
Metoprolol
Adrenergic antagonist – B1 selective >>>> B2
73
Nadolol
Adrenergic antagonist – B nonselective B1 = B2
74
- Carteolol
Adrenergic antagonist – B nonselective
75
- Levobunolol
Adrenergic antagonist – B nonselective
76
- Metipranolol
Adrenergic antagonist – B nonselective
77
Pindolol
Adrenergic antagonist – B nonselective B1 = B2
78
Propranolol
Adrenergic antagonist – B nonselective B1 = B2
79
Timolol
Adrenergic antagonist – B nonselective B1 = B2
80
a-methyldopa
False transmitter
81
Guanethidine
Synaptic vesicle depletion and membrane depolarization
82
Reserpine
Synaptic vesicle depletion (pre-junctional)
83
- Cocaine
Amine I transport inhibitor
84
- DMI (desmethyl-imipramine)
Amine I transport inhibitor
85
Tyramine
NE releasing agent
86
Pseudoephedrine
NE releasing agent
87
- Acetazolamide
Carbonic anhydrase inhibitor
88
-Dichlorphenamide
Carbonic anhydrase inhibitor
89
- Dorzolamide
Carbonic anhydrase inhibitor
90
Botulinum Toxin A
Misc. ophthalmology
91
Azathioprine
General growth inhibitor
92
Cyclophosphamide
General growth inhibitor
93
Leflunomide
General growth inhibitor
94
Methotrexate
General growth inhibitor
95
Mycophenolate mofetil
General growth inhibitor
96
Prednisone
Glucocorticoid
97
Sirolimus
mTOR inhibitor
98
Cyclosporine
Calcineurin inhibitor
99
Tacrolimus (FK506)
Calcineurin inhibitor
100
Anti-T cell globulin
Antibodies and fusion proteins
101
Alemtuzumab
Antibodies and fusion proteins
102
Basiliximab
Antibodies and fusion proteins
103
Rh (D) immune globulin
Antibodies and fusion proteins
104
Belatacept
Antibodies and fusion proteins
105
Interleukin-2
Cyokine
106
IFN-y
Cytokine
107
BCG
Adjuvant
108
Cetirizine
H1 antihist – 2nd generation
109
Cyclizine
H1 antihist – 1st generation
110
Dimenhydrinate
H1 antihist – 1st generation
111
Diphenhydramine
H1 antihist – 1st generation
112
Fexofenadine
H1 antihist – 2nd generation
113
Loratadine
H1 antihist– 2nd generation
114
Promethazine
H1 antihist – 1st generation
115
Adalimumab
Anti-TNFa agents
116
Etanercept
Anti-TNFa agents
117
Infliximab
Anti-TNFa agents
118
Anakinra
Anti-IL1 agents
119
Tofacitnib
Jak kinase inhibitors
120
Aspirin
Nonselective COX inhibitors
121
Diclofenac
Nonselective COX inhibitors
122
Diclofenac w/ misoprostol
Nonselective COX inhibitors
123
Ibuprofen
Nonselective COX inhibitors
124
Indomethacin
Nonselective COX inhibitors
125
Ketorolac
Nonselective COX inhibitors
126
Naproxen
Nonselective COX inhibitors
127
Acetaminophen
Nonselective COX inhibitors
128
Celecoxib
COX-2 selective inhibitors
129
Rofecoxib
COX-2 selective inhibitors
130
Albuterol
B2 adrenergic agonist
131
Salmeterol w/ fluticasone
B2 adrenergic agonist
132
-Beclomethasone
Corticosteroid
133
- Budesonide
Corticosteroid
134
- Fluticasone
Corticosteroid
135
- Triamclinolone
Corticosteroid
136
Prednisone
Corticosteroid
137
- Montelukast
Leukotriene modulator
138
- Zafirlukast
Leukotriene modulator
139
Zileuton
Leukotriene modulator
140
- Cromolyn
Degranulation inhibitor
141
- Nedocromil
Degranulation inhibitor
142
Ipratropium
Muscarinic cholinergic antagonist
143
Theophylline
Miscellaneous asthma

PHARM 1 Self (6 decks)

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