classic presentations Flashcards
(223 cards)
1
Q
Anti-centromere ABs
A
Scleroderma (CREST)
2
Q
Anti-desmoglein (epithelial) ABs
A
Pemphigus vulgaris (blistering)
3
Q
Anti-glomerular basement membrane ABs
A
Goodpasture’s synd. (glomerulonephritis and hemoptysis)
4
Q
Anti-histone ABs
A
Drug-induced SLE (hydralazine, isoniazid, phenytoin, procainamide)
5
Q
Anti-IgG ABs
A
Rheumatoid arthritis (syst. infl., joint lannus, boutonniere deformity)
6
Q
Anti-mitochondrial ABs (AMAs)
A
Primary biliary cirrhosis (female, cholestasis, portal HTN)
7
Q
Anti-neutrophil cytoplasmic ABs (ANCAs)
A
Vasculitis (c-ANCA: granulomatosis with polyangiitis (Wegener’s); p-ANCA: microscopic polyangiitis, Churg-Strauss synd)
8
Q
Anti-nuclear ABs (ANAs: anti-Smith and anti-dsDNA)
A
SLE (type III hypersenstivity)
9
Q
Anti-platelet ABs
A
Idiopathic thrombocytopenic purpura
10
Q
Anti-topoisomerase ABs
A
Diffuse systemic scleroderma
11
Q
Anti-transglutaminase/anti-gliadin/anti-endomysial ABs
A
Celiac DZ (diarrhea, distention, weight-loss)
12
Q
Apple Core lesion on abdominal x-ray
A
Colorectal cancer (usually left-sided)
13
Q
Azurophilic peroxidase-positive granular inclusions in granulocytes and myeloblasts
A
Auer rods (AML, especially promyelocytic [M3] type)
14
Q
Bacitracin response
A
Sensitive: S. pyogenes (A); resistant = S. agalactiae (B)
15
Q
Bamboo Spine on x-ray
A
Ankylosing spondylitis (chron. infl. arthritis: HLA-B27)
16
Q
Basophilic nuclear remnants in RBCs
A
Howell-Jolly bodies (splenectomy or non-functional spleen)
17
Q
Basophilic stippling of RBCs
A
Lead poisoning or sideroblastic anemia
18
Q
Bloody tap on LP
A
Subarachnoid hem
19
Q
Boot Shaped heart on x-ray
A
Tetralogy of Fallot; RVH
20
Q
Branching G+ rods w/sulfur granules
A
Actinomyces israelii
21
Q
Bronchogenic apical lung tumor on imaging
A
Pancoast tumor (can compress symp. gang. and cause Horner’s synd)
22
Q
Brown tumor of bone
A
Hyperparathyroidism or osteitis fibrosa cystica (deposited hemosiderin from hem. gives brown color)
23
Q
Cardiomegaly w/apical atrophy
A
Chagas’ DZ (T. cruzi)
24
Q
Cellular crescents in Bowman’s capsule
A
RPCG (crescentic glom)
25
Chocolate Cyst of ovary
Endometriosis (frequently both ovaries)
26
Circular grouping of dark tumor cells surrounding pale neurofibrils
Homer-Wright rosettes (neuroblastoma, medulloblastoma, retinoblastoma)
27
Colonies of mucoid pseudomonas in lungs
CF (auto-rec mutation in CFTR resulting in fat-soluble vitamin def. and mucous plugs)
28
Decreased alpha-fetoprotein in amniotic fluid/maternal serum
Down Synd. or other crhomosomal abnormality
29
Degeneration of dorsal columns
Tabes dorsalis (tertiary syphilis), subacute combined degeneration (dorsal columns and LCS tracts)
30
Depigmentation of neurons in substantia nigra
Parkinson's DZ (basal ganglia disorder: rigidity, resting tremor, bradykinesia)
31
Desquamated epithelium casts in sputum
Curschmann's spirals (bronchial asthma, can result in whorled mucus plugs)
32
Disarrayed granulosa cells in eosinophilic fluid
Call-Exner bodies (granulosa-theca tumor of the ovary)
33
Dysplastic squamous cervical cells with nuclear enlargement and hyperchromasia
Koilocytes (HPV - predisposes to cervical cancer)
34
Enlarged cells with intranuclear inclusion bodies
Owl's Eye appearance of CMV
35
Enlarged thyroid cells w/ground glass nuclei
Orphan Annie nuclei (papillary carc. of the thyroid)
36
Eosinophilic cytoplasmic inclusion in LIVER cell
Mallory bodies (alcoholic liver DZ)
37
Eosinophilic cytoplasmic inclusion in NERVE cell
Lewy body (Parkinson's DZ)
38
Eosinophilic globule in liver
Councilman body (toxic/viral hepatitis, often yellow fever)
39
Eosinophilic inclusion bodies in cytoplasm of HIPPOCAMPAL nerve cells
Negri bodies of rabies (Lyssavirus)
40
Extracellular amyloid deposition in gray matter of brain
Senile plaques (AD)
41
Giant B cells with bilobed nuclei with prominent inclusions ("Owl's Eye")
Reed-Sternberg cells (Hodgkin's lymphoma)
42
Glomerulus-like structure surrounding vessel in germ cells
Schiller-Duval bodies (yolk sac tumor)
43
Hair-on-end (crew cut) apperance on x-ray
beta-thallassemia, sickle cell anemia (marrow expansion)
44
hCG elevated
Choriocarcinoma, hydatidiform mole (occurs with or without embryo)
45
Heart nodules (granulomatous)
Aschoff bodies (Rheumatic fever)
46
Heterophile antibodies
Infectious Mononucleosis (EBV)
47
Hexagonal, double-pointed, needle-like crystals in bronchial secretions
Bronchial asthma (Charcot-Leyden crystals: eosinophilic granules)
48
High level of D-dimers
DVT, pulmonary embolism, DIC
49
Hilar adenopathy, periph gran. lesion in middle or lower lungs (can calcify)
Ghon complex (primary TB: mycobacterium bacilli)
50
Honeycomb lung on x-ray or CT
Interstitial pulm fibrosis
51
Hypercoagulability (leading to migrating DVTs and vasculitis)
Trousseau's synd. (adenocarcinoma of pancreas or lung)
52
Hypersegmented neutrophils
megaloblastic anemia (B12 deficiency: neurologic symptoms; folate deficiency: no neuro symptoms)
53
Hypertension, hypokalemia, metabolic acidosis
Conn's syndrome
54
Hypochromic, microcytic anemia
Iron deficiency anemia, lead poisoning, thalassemia (fetal Hb sometimes present)
55
Increased alpha-fetoprotein in amniotic fluid/maternal serum
Dating error, anencephaly, spina bifida (neural tube defects)
56
Increased uric acid levels
Gout, Lesch-Nyhan, tumor lysis synd, loop/thiazide diuretics
57
Intranuclear eosinophilic droplet-like bodies
Cowdry Type A bodies (HSV/CMV)
58
Iron-containing nodules in alveolar septum
Ferruginous bodies (asbestosis: inc. chance of mesothelioma)
59
Keratin pearls on a skin biopsy
Squamous cell carc.
60
Large lysosomal vesicles in phagocytes, immunodef.
Chediak-Higashi DZ (congenital failure of phagolysosome formation)
61
Lead Pipe appearance of colon on barium enema x-ray
Ulcerative colitis (loss of haustra)
62
Linear appearance of IgG deposition on glom. basement memb.
Goodpasture's IF results
63
Low serum ceruloplasmin
Wilson's DZ (hepatolenticular degeneration)
64
Lumpy Bumpy appearance of glomeruli on IF
post-strep glomerulonephritis (immune complex dep. of IgG and C3b)
65
Lytic "hole-punched" bone lesions on x-ray
Multiple myeloma
66
Mammary gland "blue-domed" cyst
Fibrocystic change of the breast
67
Monoclonal Ab spike
Multiple myeloma (IgG/IgA); Monoclonal gammopathy (MGUS, part of aging); Waldenstrom's (M protein = IgM) macroglobulinemia; primary amyloidosis
68
Mucin-filled cell with peripheral nucleus
Signet ring (gastric carcinoma)
69
Narrowing of bowel lumen on barium x-ray
String sign (Crohn's DZ)
70
Necrotizing vasculitis (lungs) and necrotizing glomerulonephritis
Granulomatosis w/polyangiitis (Wegener's; c-ANCA+); Goodpasture's
71
Needle-shaped, negatively birefringent crystals
Gout (monosodium urate crystals)
72
Nodular hyaline deposits on glomeruli
Kimmelsteil-Wilson nodules (Diabetic nephropathy)
73
Novobiocin response
Sensitive = s. epidermidis; resistant = s. saprophyticus
74
Nutmeg liver
Chronic passive congestion of liver due to RHF
75
Onion Skin periosteal reaction
Ewing's sarcoma (malignant round-cell tumor)
76
Optochin response
Sensitive = s. pneumoniae; Resistant = viridans strep.
77
Periosteum raised from bone, creating triangular area
Codman's triangle on x-ray (osteosarcoma, Ewing's sarcoma, pyogenic osteomyelitis
78
Podocyte fusion or "effacement" on EM
minimal change DZ (child with nephrotic synd)
79
Polished, "ivory like" appearance of bone at cartilage erosion
Eburnation (osteoarthritis resulting in bony sclerosis)
80
Protein aggregates in neurons from hyperphosphorylation of protein tau
Neurofibrillary tangles (AD) and Pick's Bodies (Pick's DZ)
81
Psammoma bodies
Meningiomas, papillary thyroid carc, mesothelioma, papillary serous carcinoma of endometrium/ovary
82
Pseudopalisading tumor cells on brain biopsy
Glioblastoma multiforme
83
RBC casts in urine
Acute glomerulonephritis
84
Rectangular, crystal-like, cytoplasmic inclusions in Leydig cells
Reinke crystals (Leydig cell tumor)
85
Renal epithelial casts in urine
Acute toxic/viral nephrosis
86
Rhomboid crystals, positively birefringent
Pseudogout (calcium pyrophosphate dihydrate crystals)
87
Rib notching
Coarctation of the aorta
88
Ring-enhancing brain lesion in AIDS
Toxoplasma gondii, CNS lymphoma
89
Sheets of medium-sized lymphoid cells with scattered pale, tingible body-laden macrophages ("starry sky" histology)
Burkitt's Lymphoma (t[8:14] c-myc activation, assoc. w/EBV; "black sky" = malignant cells
90
Silver-staining spherical aggregation of tau proteins in neurons
Pick bodies (Pick's DZ: Progressive dementia, changes in personality)
91
Soap Bubble in femur or tibia on x-ray
Giant-cell tumor of bone (generally benign)
92
Spikes on BM, "dome-like" subepithelial deposits
Membranous glomerulonephritis (may progress to nephrotic synd)
93
Stacks of RBCs
Rouleaux formation (High ESR, multiple myeloma)
94
Stripped vaginal epithelial cells
Clue cells (gardnerella vaginalis)
95
Tennis Racket shaped cytoplasmic organelles (EM) in Langerhans cells
Birbeck granules (Langerhans cell histiocytosis or histiocytosis X: eosinophilic granuloma
96
Thrombi made of white/red layers
Lines of Zahn (arterial thrombus, layers of platelets/RBCs)
97
Thumb Sign on lateral x-ray
Epiglotitis (H. influenzae)
98
Thyroid-like apperance of kidney
Chronic bacterial pyelonephritis
99
Tram-track appearance of capillary loops of glomerular BM on light microscopy
Membranoproliferative GN
100
Triglyceride accumulation in liver cell vacuoles
Fatty liver DZ (alcoholic or metabolic synd)
101
Waxy casts with very low urine flow
Chronic end-stage renal DZ
102
WBC casts in urine
Acute pyelonephritis
103
WBCs that look "smudged"
CLL (almost always B cell)
104
Wire loop glomerular capillary appearance on light microscopy
Lupus nephropathy
105
Yellowish CSF
Xanthochromia (eg, due to subarachnoid hem)
106
Abdom pain, ascites, hepatomegaly
Budd-Chiari synd. (post-hepatic venous thrombosis)
107
Achilles tendon xanthoma
Familial hypercholest. (decreased LDL receptor signaling)
108
Adrenal hemorrhage, hypotension, DIC
Waterhouse-Friderichsen synd (meningococcemia)
109
Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints
Marfan's synd (fibrillin defect)
110
Athlete with polycythemia
Secondary to erythropoietin injection
111
Back pain, fever, night sweats, weight loss
Pott's DZ (vertebral tuberculosis)
112
Bilateral hilar adenopathy, uveitis
Sarcoidosis (non-caseating granulomas)
113
Blue sclera
Osteogenisis imperfecta (type 1 collagen defect)
114
Bluish line on gingiva
Burton's line (lead poisoning)
115
Bone pain, bone enlargement, arthritis
Paget's DZ of bone (increased osteoblastic & osteoclastic activity)
116
Bounding pulses, diastolic heart murmur, head bobbing
Aortic regurgitation
117
Butterfly facial rash and Raynaud's phenomenon in young female
SLE
118
Cafe-au-lait spots, Lisch nodules (iris hamartoma)
Neurofibromatosis Type 1 (+ pheochromocytoma, optic gliomas)
119
Cafe-au-lait spots, polyostotic fibrous dysplasia, precocious puberty, multiple endocrine abnormalities
McCune-Albright synd. (mosaic G-protein signaling mutation)
120
Calf pseudohypertrophy
MD (eg, Duchenne's): X-linked recessive deletion of dystrophin gene
121
Cherry-red spot on macula
Tay-Sachs (ganglioside accumulation) or Neimann-Pick (sphingomyelin accumulation, central retinal artery occlusion
122
Chest pain on exertion
Angina (Stable: with moderate exertion; unstable: with minimal exertion)
123
Chest pain, pericardial effusion/friction rub, persistent fever following MI
Dressler's synd (auto-imm. post-MI fibrinous pericarditis, 1-12 wks after MI)
124
Child uses arms to stand up from squat
Gower's sign (Duchenne MD)
125
Child w/fever later develops red rash on face that spreads to body
Slapped Cheeks sign (erythema infectiousum/ fifth DZ/ parvovirus B19)
126
Chorea, dementia, caudate degeneration
Huntington's DZ (auto-dom CAG repeat expansion)
127
Chronic exercise intolerance w/myalgia, fatigue, painful cramps, myoglobinuria
McArdle's DZ (muscle glycogen phosphorylase deficiency)
128
Cold intolerance
Hypothyroidism
129
Conjugate lateral gaze palsy, horizontal diploplia
Internuclear ophthalmoplegia (damage to MLF; bilateral = MS; unilateral = stroke)
130
Continuous "machinery" heart murmur
PDA (close with indomethacin; open to maintain with misoprostol)
131
Cutaneous/dermal edema due to connective tissue deposition
Myxedema (caused by hypo-thyroidism, Graves' disease (pre-tibial)
132
Dark purple nodules on skin/mouth
Kaposi's sarcoma (usually AIDS pts [MSM]; associated w/HHV8
133
Deep, labored breathing/hyperventilation
Kussmaul breathing (DKA)
134
Dermatitis, dementia, diarrhea
Pellagra (niacin [vitamin B3] deficiency)
135
Dilated cardiomyopathy, edema, alcoholism or malnutrition
Wet beriberi (thiamine [vitamin B1] deficiency)
136
Dog or cate bite resulting in infection
Pasteurella multicoda (cellulitis @ inoculation site)
137
Dry eyes, dry mouth, arthritis
Sjogren's Synd. (Auto-imm. destruction of exocrine glands)
138
Dysphagia (esophageal webs), glossitis, iron deficiency anemia
Plummer-Vinson synd. (may progress to esophageal Sq. CC)
139
Elastic skin, hypermobility of joints
Ehlers-Danlos synd (Type 3 Collagen defect)
140
Enlarged hard left supraclavicular node
Virchow's node (abdominal metastasis)
141
Erthryderma, lymphadenopathy, hepatosplenomegaly, atypical T cells
Sezary synd. (cutaneous T-cell lymphoma) or mycosis fungoides
142
Facial muscle spasm upon tapping
Chvostek's sign (hypocalcemia)
143
Fat, female, forty, and fertile
Cholelithiasis (gallstones) risk factors
144
Fever, chills, headache, myalgia following antibiotic treatment for syphilis
Jarisch-Herxheimer rxn (rapid lysis of spirochetes results in toxin release)
145
Fever, cough, conjunctivitis, coryza, diffuse rash
Measles (morbillivirus)
146
Fever, night sweats, weight loss
B symptoms (staging) of lymphoma
147
Fibrous plaques in soft tissue of penis
Peyronie's DZ (connective tissue disorder)
148
Gout, mental retardation, self-mutilating behavior in a boy
Lesch-Nyhan synd (HGPRT deficiency, X-linked recessive)
149
Green-yellow rings around peripheral cornea
Kayser-Fleischer rings (copper accumulation from Wilson's DZ)
150
Hamartomatous GI polyps, hyperpigmentation of mouth/feet/hands
Peutz-Jeghers synd (inherited, benign polyposis can cause bowel obstruction, GI cancer risk)
151
Hepatosplenomegaly, osteoporosis, neurologic symptoms
Gaucher's DZ (glucocerebrosidase deficiency)
152
Hereditary nephritis, sensorineural hearing loss, cataracts
Alport syndrome (mutation in alpha chain of Collegen 4)
153
Hyperphagia, hypersexuality, hyperorality, hyperdocility
Kluver-Bucy synd (bilateral amygdala lesion)
154
Hyperreflexia, hypertonia, Babinski sign present
UMN damage
155
Hyporeflexia, hypotonia, atrophy, fasciculations
LMN damage
156
Hypoxemia, polycythemia, hypercapnia
Blue bloater (chronic bronchitis: hyperplasia of mucous cells)
157
Indurated, ulcerated genital lesion
Nonpainful = chancre (primary syphilis, T. Pallidum); Painful w/exudate = chancroid (h. ducreyi)
158
Infant w/cleft lip/palate, microcephaly or holoprosencephaly, polydactyly, cutis aplasia
Patau's synd (trisomy 13)
159
Infant w/failure to thrive, hepatosplenomegaly, and neurodegeneration
Niemann-Pick DZ (genetic sphingomyelinase deficiency)
160
Infant w/hypoglycemia, failure to thrive, hepatomegaly
Cori's disease (debranching enzyme deficiency)
161
Infant w/microcephaly, rocker-bottom feet, clenched hands, structural heart defect
Edward's synd (Trisomy 18)
162
Jaundice, palpable distended non-tender gallbladder
Courvoisier's sign (distal obstruction of biliary tree)
163
Large rash w/Bull's eye appearance
Erythema chronicum migrans from Ixodes tick bite (Lyme disease: Borrelia)
164
Lucid interval after traumatic brain injury
Epidural hematoma (middle meningeal artery rupture)
165
Male child, recurrent infections, no mature B cells
Bruton's DZ (X-linked agammaglobulinemia)
166
Mucosal bleeding and prolonged bleeding time
Glanzmann's thrombasthenia (defect in platelet aggregation due to lack of Gp2b/3a)
167
Muffled heart sounds, distended neck veins, hypotension
Beck's triad of cardiac tamponade
168
Multiple colon polyps, osteomas/soft tissue tumors, impacted supernumerary teeth
Gardner's synd (subtype of FAP)
169
Myopathy (infantile hypertrophic cardiomyopathy), exercise intolerance
Pompe's DZ (lysosomal alpha-1,4-glucosidase deficiency)
170
Neonate w/arm paralysis following difficult birth
Erb-Duchenne palsy (superior trunk [C5-C6] brachial plexus injury: "waiter's tip" hand)
171
No lactation postpoartum, absent menstruation, cold intolerance
Sheehan's syndrome (pituitary infarction)
172
Nystagmus, intention tremor, scanning speech, bilateral internuclear ophthalmoplegia
MS
173
Oscillating slow/fast breathing
Cheyne-Stokes respirations (central apnea in CHF or increased ICP)
174
Painful blue fingers/toes, hemolytic anemia
Cold agglutinin DZ (auto-imm hemolytic anemia from M. pneumoniae, mono)
175
Painful, pale, cold fingers/toes
Reynaud's phenomenon (vasospasm in extremities)
176
Painful, raised red lesions on pad of fingers/toes
Osler's node (infective endocarditis, immune complex deposition)
177
Painless erythematous lesions in palms and soles
Janeway lesions (infective endocarditis, septic emboli, microabscesses)
178
Painless jaundice
Cancer of pancreatic head obstructing bile duct
179
Palpable purpura on buttocks/legs, joint pain, abdominal pain (child), hematuria
Henoch-Schonlein purpura (IgA vasculitis affecting skin and kidneys)
180
Pancreatic, pituitary, parathyroid tumors
MEN 1 (auto-dom)
181
Periorbital and/or peripheral edema, proteinuria, hypoalbuminemia, hypercholesterolemia
Nephrotic synd.
182
Pink complexion, dyspnea, hyperventilation
Pink puffer (emphysema: centriacinar [smoking]; panacinar [a1aT deficiency])
183
Polyuria, renal tubular acidosis Type 2, growth failure, electrolyte imbalances, hypophosphatemic rickets
Fanconi's Synd (proximal tubular reabsorption defect)
184
Positive anterior "drawer sign"
ACL injury
185
pruritic, purple, polygonal, planar papules and plaques (6 P's)
Lichen Planus
186
ptosis, miosis, anhidrosis
Horner's synd (sympathetic chain lesion)
187
pupil accommodates but doesn't react
Argyll Robertson pupil (neurosyphilis)
188
Rapidly progressive leg weakness that ascends following GI/URI
Guillain-Barre synd (acute auto-imm inflammatory demyelinating polyneuropathy)
189
Rash on palms and soles
Coxsackie A, secondary syphilis, Rocky Mountain Spotted Fever
190
Recurrent colds, unusual eczema, high serum IgE
Hyper-IgE synd (Job's synd: neutrophil chemotaxis abnormality)
191
Red "currant jelly" sputum in alcoholic or diabetic patients
Klebsiella pneumoniae
192
Red "currant jelly" stools
Acute mesenteric ischemia (adults), intussusception (infants)
193
Red, itchy swollen rash of nipple/areola
Paget's DZ of breast (represents underlying neoplasm)
194
Red urine in the morning, fragile RBCs
Paroxysmal nocturnal hemoglobinuria
195
Renal cell carcinoma (bilateral), hemangioblastomas, angiomatosis, pheochromocytoma
von Hippel-Lindau DZ (dominant tumor suppressor gene mutation)
196
Resting tremor, rigidity, akinesia, postural instability
Parkins's DZ (nigrostriatal dopamine depletion)
197
Retinal hemorrhages with pale centers
Roth's spots (bacterial endocarditis)
198
Severe jaundice in neonate
Crigler-Najjar synd. (congenital unconjugated hyperbilirubinemia)
199
Severe RLQ pain with palpation of LLQ
Rovsing's sign (acute appendicitis)
200
Severe RLQ pain with rebound tenderness
McBurney's sign (acute appendicitis)
201
Short stature, increased incidence of tumors/leukemia, aplastic anemia
Fanconi's Anemia (genetic loss of DNA crosslink repair, often progresses to AML)
202
Single palmar crease
Simian crease (Down syndrome)
203
Situs inversus, chronic sinusitis, bronchiectasis, infertility
Kartagener's synd. (dynein arm defect affecting cilia)
204
Skin hyperpigmentation, hypotension, fatigue
Addision's DZ (primary adrenocortical insufficiency causes increased ACTH and increased alpha MSH production)
205
Slow, progressive muscle weakness in boys
Becker's MD (X-linked missense mutation in dystrophin; less severe than Duchenne)
206
Small, irregular red spots on buccal/lingual mucosa with blue-white centers
Koplik spots (measles; rubeola virus)
207
Smooth, flat, moist, painless white lesions on genitals
Condylomata lata (secondary syphilis)
208
Splinter hemorrhages in fingernails
Bacterial endocarditis
209
Strawberry tongue
Scarlet fever, Kawasaki DZ, toxic shock synd.
210
Streak ovaries, convenital heart DZ, horseshoe kidney, cystic hygroma at birth, short stature, webbed neck, lymphedema
Turner synd. (45, XO)
211
Sudden swollen/painful big toe joint, tophi
Gout/podagra (hyperuricemia)
212
Swollen gums, mucosal bleeding, poor wound healing, spots on skin
Scurvy (vitamin C deficiency: can't hydroxylate proline/lysine for collagen synthesis)
213
Swollen, hard, painful finger joints
Osteoarthritis (osteophytes on PIP [Bouchard's nodes], DIP [Heberden's nodes])
214
Systolic ejection murmur
Aortic valve stenosis
215
Thyroid and parathyroid tumors, pheochromocytoma
MEN 2A (auto-dom ret mutation)
216
Thyroid tumors, pheochromocytoma, ganglioneuromatosis
MEN 2B (auto-dom ret mutation)
217
Toe extension/fanning upon plantar scrape
Babinski sign (UMN lesion)
218
Unilateral facial drooping involving forehead
Facial nerve (LMN CN 7 palsy)
219
Urethritis, conjunctivitis, arthritis in a male
Reactive arthritis associated with HLA-B27
220
Vascular birthmark (port-wine stain)
Hemangioma (benign, but associated with Sturge-Weber synd.)
221
Vomiting blood following gastroesophageal lacerations
Mallory-Weiss syndrome (alcoholic and bulimic pts)
222
Weight loss, diarrhea, arthritis, fever, adenopathy
Whipple's DZ (Tropheryma whipplei)
223
Worst headache of my life
Subarachnoid hemorrage
