Classic/Relevant Treatments Flashcards Preview

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Flashcards in Classic/Relevant Treatments Deck (88):
1

Absence seizures

Ethosuximide

2

Acute gout attach

NSAIDs, colchicine, glucocorticoids

3

Acute promyelocytic leukemia (M3)

All-trans retinoic acid

4

ADHD

Methylphenidate, CBT, atomoxetine, guanfacine, clonidine

5

Alcoholism

Disulfiram, acamprosate, naltrexone, supportive care

6

Alcohol Withdrawal

Long-acting benzodiazepines

7

Anorexia

Nutrition, psychotherapy, mirtazapine

8

Arrhythmia in damaged cardiac tissue

Class IB antiarrhythmic (lidocaine, mexiletine)

9

Benign prostatic hyperplasia

α1-antagonists, 5α-reductase inhibitors, PDE-5 inhibitors

10

Bipolar Disorder

Mood stabilizers (ex: lithium, valproic acid, carbamazepine), atypical antipsychotics

11

Breast cancer in postmenopausal women

Aromatase inhibitor (anastrozole)

12

Buerger disease

Smoking cessation

13

Bulimia nervosa

SSRIs

14

Candida albicans

Topical azoles (vaginitis); nystatin, fluconazole, caspofungin (oral/esophageal); fluconazole, caspofungin, amphotericin B (systemic)

15

Carcinoid syndrome

Octreotide

16

Chlamydia trachomatis

Doxycycline (+ ceftriaxone for gonorrhea co-infection), erythromycin eye drops (prophylaxis in infants)

17

Chronic gout

Xanthine oxidase inhibitors (eg, allopurinol, febuxostat); pegloticase; probenecid

18

Chronic hepatitis B or C

INF-α, (HBV and HCV); ribavirin, simpeprevir, sofosbuvir (HCV)

19

Chronic myelogenous leukemia

Imatinib

20

Clostridium botulinum

Antitoxin

21

Clostridium difficile

Oral metronidazole; if refractory, oral vancomycin

22

Clostridium tetani

Antitoxin

23

CMV

Corticosteroids, infliximab, azathioprine

24

Cryptococcus neoformans

Fluconazole (in AIDS patients)

25

Cyclophosphamide-induced hemorrhagic cystitis

Mesna

26

Depression

SSRIs (first-line)

27

Diabetes insipidus

Desmopressin (central); hydrochlorothiazide, indomethacin, amiloride (nephrogenic)

28

Diabetes mellitus type I

Dietary intervention (low carbohydrate) + insulin replacement

29

Diabetes mellitus type II

Dietary intervention, oral hypoglycemics, and insulin (if refractory)

30

Diabetic ketoacidosis

Fluids, insulin, K+

31

Drug of choice for anticoagulation during pregnancy

Heparin

32

Enterococci

Vancomycin, aminopenicillins/cephalosporins

33

Erectile dysfunction

Sildenafil, tadalafil, vardenafil

34

ER + breast cancer

Tamoxifen

35

Ethylene glycol/methanol intoxication

Fomepizole (alcohol dehydrogenase inhibitor)

36

Haemophilus influenzae (B)

Rifampin (prophylaxis)

37

Generalized anxiety disorder

SSRIs, SNRIs (first line); buspirone (second line)

38

Granulomatosis with polyangiitis

Cyclophosphamide, corticosteroids

39

Heparin reversal

Protamine sulfate

40

HER2/neu + breast cancer

Trastuzumab

41

Hyperaldosteronism

Spironolactone

42

Hyperchlolesterolemia

Statin (first-time)

43

Hypertriglyceridemia

Fibrate

44

Immediate anticoagulation

Heparin

45

Infertility

Leuprolide, GnRH (pulsatile), clomiphene

46

Influenza

Oseltamivir, zanamivir

47

Kawasaki disease

IVIV, high-dose aspirin

48

Legionella pneumophila

Macrolides (ex. azithromycin)

49

Long-term anticoagulation

Warfarin, dabigatran, rivaroxaban, and apixaban

50

Malaria

Chloroquine, mefloquine, atovaquone/proguanil (for blood schizont), primaquine (for liver hypnozoite)

51

Malignant hyperthermia

Dantrolene

52

Medical abortion

Mifepristone

53

Migraine

Abortive therapies (ex. sumatriptan, NSAIDs); prophylaxis (ex. propranolol, topiramate, CCBs, amitriptyline)

54

Multiple sclerosis

Disease-modifying therapies (ex. β-interferon, natalizumab); for acute flare, use IV steroids

55

Mycobacterium tuberulosis

RIPE (rifampin, isoniazid, pyrazinamide, ethambutol)

56

Neisseria gonorrhoeae

Ceftriaxone (add doxycycline to cover likely concurrent C. trachomatis)

57

Neisseria meningitidis

Penicillin/ceftriaxone, rifampin (prophylaxis)

58

Neural tube defect prevention

Prenatal folic acid

59

Osteomalacia/rickets

Vitamin D supplementation

60

Osteoporosis

Calcium/vitamin D supplementation (prophylaxis); bisphosphonates, PTH analogs, SREMs, calcitonin, denosumab (treatment)

61

Patent ductus arteriosus

Close with indomethacin; keep open with PGE analogs

62

Pheochromocytoma

α-antagonists (eg. phenoxybenzamine)

63

Pneumocystis jirovecii

TMP-SMX (prophylaxis and treatment in immunosuppressed patients)

64

Prolactinoma

Cabergoline/bromocriptine (dopamine agonists)

65

Prostate adenocarcinoma/uterine fibroids

Leuprolide, GnRH (continuous)

66

Prostate adenocarcinoma

Flutamide

67

Pseudomonas aeruginosa

Antipseudomonal penicillins, aminoglycosides, carbapenems

68

Pulmonary arterial hypertension (idioapthic)

Sildenafil, bosentan, epoprostenol

69

Rickettsia rickettsii

Doxycycline, chloramphenicol

70

Schizophrenia (negative symptoms)

Atypical antipsychotics

71

Schizophrenia (positive symptoms)

Typical and Atypical antipsychotics

72

SIADH

Fluid restriction, IV hypertonic saline, conivaptan/tolvaptan, demeclocycline

73

Sickle Cell Disease

Hydroxyurea (increase fetal hemoglobin)

74

Sporothrix schenckii

Itraconazole, oral potassium iodide

75

Stable angina

Sublingual nitroglycerin

76

Staphylococcus aureus

MSSA: nafcillin, oxacillin, dicloxacillin (antistaphylococcal penicillins) MRSA: vancomycin, daptomycin, linezolid, ceftaroline

77

Streptococcus bovis

Penicillin prophylaxis; evaluation for colon cancer if linked to endocarditis

78

Streptococcus pneumoniae

Penicillin/cephalosporin (systemic infection, pneumonia), vancomycin (meningitis)

79

Streptococcus pyogenes

Penicillin prophylaxis

80

Temporal arteritis

High-dose steroids

81

Tonic-clonic seizures

Levetiracetam, phenytoin, valproate, carbamazepine

82

Toxoplasma gondii

Sulfadiazine + pyrimethamine

83

Treponema pallidum

Penicillin

84

Trichomonas vaginalis

Metronidazole (patient and partner)

85

Trigeminal neuralgia (tic deouloureux)

Carbamazepine

86

Ulcerative Colitis

5-ASA preparations (ex. mesalamine), 6-mercaptopurine, infliximab, colectomy

87

UTI prophylaxis

TMP-SMX

88

Warfarin reversal

Fresh frozen plasma (acute), vitamin K (non-acute)