Clinical Breast Examination Flashcards

1
Q

what hormone is responsible for growth of adipose tissue and lactiferous ducts?

A

estrogen

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2
Q

what hormone is responsible for growth of lobules and alveolar budding?

A

progesterone

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3
Q

what are the most common breast complaints?

A

pain

mass

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4
Q

risk factors for breast cancer

A
age
personal hx of breast cancer
hx of atypical hyperplasia
high breast tissue density
first degree relative with breast or ovarian CA
early menarche (< 12)
late menopause (>55)
no term pregnancies
never breastfed
long-term use of OCP
post-menopausal obesity
alcohol consumption (yikes)
tall height
high SES
Ashkenazi jew
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5
Q

what is included in a complete breast exam?

A

both breast evaluated including axilla and chest wall

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6
Q

when do women get their first mammogram?

A

40-50 y/o

earlier if have a complaint or breast mass

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7
Q

What are other tools that can be used for breast dx?

A

US - useful for inconclusive mammogram, young women, or women with dense breasts, fine needle biopsy

MRI - adjunct to mammogram in suspicious masses, CA diagnosis, BRCA carriers

fine needle aspiration biopsy - cyst vs solid mass

core needle biopsy - solid mass dx

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8
Q

cyclical mastalgia

A

breast pain that starts at the luteal phase of the menstrual cycle and ends after onset of menses

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9
Q

noncyclical mastalgia

A

breast pain secondary to tumors, mastitis, cysts or medications

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10
Q

treatment for mastalgia

A
*danazol* (only FDA approved)
SERMs
OCP
Depo Provera
sx relief
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11
Q

nipple discharge could indicate what?

A

usually benign breast dz

could be sign of endocrine or CA

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12
Q

bloody nipple discharge could indicate what?

A

cancer until proven otherwise

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13
Q

breast mass signs concerning for malignancy

A
> 2cm
immobile
poorly defined margins
firmness
dimpling/retraction/color changes
bloody discharge
ipsilateral LAD
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14
Q

common non-proliferative breast masses

A

fibroadenoma - most common

galactocele - occurs with lactation

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15
Q

common proliferative without atypia breast masses

A

epithelial hyperplasia
sclerosing adenosis
complex sclerosing lesions
papillomas

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16
Q

common proliferative with atypia breast masses

A

lobular carcinoma in situ (LCIS)

ductal carcinoma in situ (DCIS)

17
Q

treatment for LCIS and DCIS

A

excision + SERMs

18
Q

screening tool to assess for breast cancer risk

A

Gail Model

19
Q

what is the most important indicator of prognosis in breast cancer?

A

stage at diagnosis

20
Q

breast cancer treatments

A
lumpectomy + radiation
mastectomy
chemotherapy
SERMs (ER+)
aromatase inhibitors
Herceptin (HER2+)