Clinical Chemistry Flashcards
(115 cards)
1
Q
Abrupt change in the mean
A
Shift
2
Q
6 values continue to increase/decrease
A
Trend
3
Q
Vertical line (y-axis)
A
Dependent variable
4
Q
Major apolipoprotein of chylomicrons
A
Apo B48
5
Q
Transferin, hemopexin, complement
A
Beta globulins
6
Q
UV region
A
<400 nm
7
Q
Most concentrated NPN
A
Urea
8
Q
Enzyme category of 5’-nucleotidase
A
Hydrolase
9
Q
CK-MB will begin to rise after
A
4-6 hours
10
Q
Metal with high affinity to keratin
A
Arsenic
11
Q
Determine difference between SD of 2 groups of data
A
F-test
12
Q
Treatment for various seizure disorders
A
Carbamazepine
13
Q
Emphysema causes what acid-base disorder
A
Respiratory acidosis
14
Q
Used for measuring pH and pCO2
A
Potentiometry
15
Q
Effect of increased glucose to sodium
A
Decreased sodium
16
Q
Conversion factor of BUN to UREA
A
2.14
17
Q
Increased growth hormone in children
A
Gigantism
18
Q
Blood alcohol level of 0.35-0.50%
A
Coma and possible death
19
Q
Reverse metabolism for LDH
A
Wrobleuski La Due
20
Q
Substrate in Bowers and McComb (ALP)
A
p-nitrophenylphosphate (PNPP)
21
Q
Vertical position when not in use
A
Horizontal centrifuge
22
Q
Lipoprotein with the least density
A
Chylomicrons
23
Q
Beta-gamma bridging
A
Liver cirrhosis
24
Q
% Blood alcohol: Impaired consciousness
A
0.27-0.40
25
BMI of underweight
<18.5 kg/m^2
26
Enzyme classification of G6PD
Oxidoreductase
27
Depends on substrate concentration
First order kinetics
28
Phosphomolybdate reagent
Folin-Wu
29
Uses common reaction vessel
Continuous flow analyzer
30
Middle or midpoint value
Median
31
10% bleach inactivates HBV in
10 minutes
32
Copper-binding glycoprotein
Ceruloplasmin
33
Odor of bitter almonds
Cyanide poisoning
34
Confirmatory test for acromegaly
Glucose-suppression - OGTT (75g)
35
Sample used in external QC
Blind sample
36
Very FAR from a set of control values
Outlier
37
Methylenedioxymethampethamine
Ecstasy
38
Common specimen used for POCT
Capillary blood
39
CTAD anticoagulant is used for
Coagulation studies
40
Part of "glucose tolerance factor"
Chromium
41
8 values on one side of the mean
8x
42
Enzyme classification of aldolase
Lyase
43
Most heat-labile isoenzyme
Bone
44
Ideal fasting time for lipid studies
12 hours
45
Highest CK activity is seen in
Duchenne's muscular dystrophy
46
Non protein molecule for enzyme activity
Cofactor
47
E + S = ES = E + P
Enzyme catalytic reaction
48
Enzyme increased in chronic alcoholism
GGT
49
Hypernatremia when serum Na is
>145 mmol/L
50
Electrode used for potassium (K)
Valinomycin-based electrode
51
Generally used reagent water type
Type 2
52
Conversion factor for cholesterol
0.026
53
BMI of overweight individuals
25 - 29.9
54
3 step method for cholesterol determination
Abell-Kendal
55
Relative concentration of a solution
Dilution
56
Known as the "master gland"
Pituitary gland
57
Enzyme used for rape investigation
ACP
58
Cause of relative hyperproteinemia
Dehydration
59
Kernicterus is accumulation of bilirubin in the
Brain tissues
60
Compare previous specimen from recent result
Delta check
61
Most common cause of hyperkalemia
Impaired renal excretion
62
Reverse method for CK
Oliver-Rosalki
63
Zona glomerulosa produces
Mineralocorticoids (e.g. Aldosterone)
64
Vitamin C deficiency leads to
Scurvy
65
Critical level for hyperkalemia
>6.5 mEq/L
66
Most potent androgen
Testosterone/dihydrotestosterone
67
Marked hyperkalemia may lead to
Cardiac arrest
68
Odor of garlic breath toxicity
Arsenic toxicity
69
Reference method for measurement of urea
IDMS
70
Increased cortisol, increased ACTH
Cushing's disease
71
Electrolytes for neuromuscular excitability
K, Ca, Mg
72
Theophylline and theobromine are
Bronchodilators
73
Panic value for high bicarbonate
>40 mEq/L
74
Screening test for acromegaly
Somatomedin-C
75
Jaundice is evident when bilirubin is
>2 mg/dL
76
Non-destructive technique for lipoprotein particles deficiency
Nuclear magnetic resonance spectrophotometry (NMRS)
77
A/G ratio in multiple myeloma and cirrhosis
Low
78
Method for measurement of metanephrine and normetanephrine
Pisano method
79
Main cause of QC shift
Improper calibration of instrument
80
Legally intoxicated blood alcohol level
100 mg/dL or higher
81
It uses fluorophore-labeled thyroxine
FPIA (fluorescence polarization immunoassay)
82
Vitamin B3 deficiency may lead to
Pellagra
83
Effect of amino acids on GH secretion
Increased
84
Transportation of drug from administration site to blood
Adsorption
85
Effect of thrombocytosis on serum potassium
Increased
86
Electrolyte for myocardial rhythm and contraction
K, Ca, Mg
87
Effect of hypercalcemia on AG
Decreased
88
Electrolyte maintaining electroneutrality
Chloride
89
Enzyme classification of cholineesterase
Hydrolase
90
BUN and creatinine are significantly increased if GFR is
Decreased by at least 50%
91
Overzealous treatment of DM may lead to
Hypoglycemia
92
Lipoprotein found in obstructive jaundice, LCAT deficiency
Lipoprotein x
93
LFT for hepatocellular damage and necrosis
Serum AST levels (Widmann)
94
Unit prefix for 1 million (1x10^6)
Mega
95
Cause of hyperglycemia during pregnancy
Hormonal changes
96
Why is plasma not preferred for SPE
Due to pseudo beta-gamma bridging effect
97
Peak absorbance of uric acid happens at what wavelength
285 nm
98
Reflects lowest drug concentration in blood
Trough concentration
99
Temperature of analyzer (random/systematic)
Random error
100
Uses luminol and luminometer for T4
Chemiluminiscence
101
3M urea inhibits what ALP isoenzyme
Bone ALP
102
Most prominent benzodiazepine
Valium
103
Is pentazocine natural or synthetic
Synthetic
104
Numerator in H-H equation reflects
Kidney (bicarbonate reabsorption)
105
Alpha 1,4-glucosidase deficiency
Pompe disease
106
To establish DM symptoms, RBS should be
>200 mg/dL
107
Conversion factor of ammonia
0.587
108
Major advantage of centrifugal analysis
Batch analysis
109
Borderline high for TAG
150-199 mg/dL
110
Marker for bone resorption
Cross-linked C telopeptide
111
10-fold increase in AMG is seen in
Nephrotic syndrome
112
Effect of salicylate poisoning on AG
Increased
113
1st responder to stress within seconds
Catecholamines
114
IC iron transporter: int surface to inside cell
DMT-1
115
Electrolyte, BUN, crea, osmolality done. Next?
Determine osmolal gap
