Hematology Flashcards

(113 cards)

1
Q

A medical technologist was performing erythrocyte morphology evaluation and observed 10 to 20 stomatocytes per oil immersion field. This is graded as

A

2+

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2
Q

Codocytes graded as 3+

A

Greater than 20 per field

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3
Q

Codocytes: 41 per OIF

A

3+

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4
Q

A microscopist saw at least 5-10 acanthocytes per oil immersion field. The medical technologist should report it as

A

2+

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5
Q

A peripheral blood smear was reported to have 2+ schistocytes. How many of the said poikilocyte is expected to be seen per OIF

A

5-10

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6
Q

Twelve (12) RBCs with basophilic stippling were seen on a blood smear. How do you report this finding

A

Positive

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7
Q

Pathway that provides reduced glutathione

A

Hexose monophosphate shunt / PPP

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8
Q

WBC count is <3.0, what is the dilution

A

1:10

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9
Q

Length of capillary tube

A

7.0-7.5 cm (70-75 mm)

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10
Q

Zone that maintains the platelet shape

A

Sol-gel-zone

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11
Q

5-15 degrees light scatter

A

High angle forward scatter

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12
Q

Stomatocyte grading of 2+

A

10-20/ OIF (or 11-20/field)

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13
Q

> 11% of cells are polychromatophilic

A

4+

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14
Q

Test for CGD

A

NBT dye test

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15
Q

Positive instrumental errors

A

Bubbles on the sample
Extraneous electrical current
Aperture plugs

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16
Q

“Wheel spoke” chromatin pattern

A

Basophilic normoblast

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17
Q

Platelet structure that contains alpha granules

A

Organelle zone

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18
Q

Quantity of reagent used in PT

A

200 ul (0.2 mL)

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19
Q

Principle of Coulter and Sysmex

A

Electrical impedance

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20
Q

Seepage of blood into large areas

A

Ecchymosis

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21
Q

Leukemia associated with DIC

A

M3

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22
Q

Rouleaux grading aggregates of 3-4 RBC

A

1+

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23
Q

Thin rim of hemoglobin

A

4+

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24
Q

Negative instrumental error

A

Excessive lysing of RBCs

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25
Derived from platelet histogram
MPV and PDW
26
Normal anticoagulant in the body
Heparin
27
Wavelength in cyanmethemoglobin method
540 nm
28
(+) Philadelphia chromosome
Good prognosis
29
Visual detection of clot formation
Tilt tube
30
Improper setting of aperture current/threshold
Positive or negative error
31
Large, homogenous lymphocytes
L3
32
Size of blood drop for smear preparation
2-3 mm
33
Acute monoblastic leukemia
M5
34
2 zeta 2 gamma, what hemoglobin
Portland
35
>20 codocytes per field
3+
36
Platelet estimated of 100,000-149,000 / uL
Slight decrease
37
Also known as congenital pure red cell aplasia
Diamond-Blackfan anemia
38
Alder-Reilly granules are PAS
Positive
39
Sticking of platelets to one another
Platelet aggregation
40
Cytochemical stain (+) in L1, L2, and M6
PAS
41
Ohm's law
Voltage = current x resistance
42
Adjusted Drabkin's reagent platelet count is
>700 x 10^9/L
43
Abnormal iron granulocyte in RBCs in Wright stain
Pappenheimer bodies
44
Monocyte that is (+) with PAS stain
Gaucher cell
45
Undergoes 1st stage of endomitosis
LD-CFU-Meg
46
In uremia, platelet function is impaired due to
Nitric oxide (NO)
47
Maturation time of eosinophils
3.5 days
48
Standard dilution for platelet count
1:100
49
Normal template bleeding time
6-10 minutes
50
Smear slide angle if patient has polycythemia vera
25 degrees
51
Cell cycle: DNA replication occurs
Synthesis (S) stage
52
Objective used for snow plow effect
LPO
53
Principle involved in dithionite test
Reduction
54
Largest cell in the bone marrow
Megakaryocyte
55
Components of flow cytometer
Computer Optics Fluidics Electronics
56
Test for quantitating Factor VIII inhibitor
Bethesda assay
57
Allow platelets to settle in hemocytometer for
15 minutes
58
Allow WBCs to settle in hemocytometer for
10 minutes
59
If buffer is too acidic, RBCs are
Too pink
60
Dithionite is a screening test for
Hemoglobin S
61
Solid tumor counterpart of ALL
Lymphoma (poorly differentiated)
62
Relationship between ESR and RBC mass
Directly proportional
63
Dacryocytes are associated with
Myelofibrosis
64
Increase PT and APTT, NC by normal plasma
Circulating (lupus) anticoagulant
65
MPV is measured at what period
1-3 hours after blood collection
66
If platelet count is low, MPV is
High
67
Microhematocrit tubes should be read within
10 minutes after centrifugation
68
Erythroid cell with "checkerboard" nucleus
Polychromatophilic normoblast
69
Tertiary granules are 1st produced in
Metamyelocyte
70
LAP activity on CML
Decreased
71
Also known as "Plasma thromboplastin component"
Factor IX
72
Major cause of death in sickle cell anemia
Bacterial infection
73
Dendritic cell originated from
Common lymphoid progenitor cell
74
Reticulated platelets are seen in
Immune thrombocytopenic purpura
75
Acute Basophilic Leukemia
M8
76
Pince-nez nucleus
Heterozygous Pelger-Huet anomaly
77
Needle gauge for pediatric phlebotomy
Gauge 23
78
Trapped plasma increase hematocrit by
1-3%
79
Acute erythroleukemia
M6
80
Zone than contains mitochondria
Organelle zone
81
PT and APTT result in polycythemia
Both prolonged
82
ESR reference sample not returned to RT
Increased
83
ESR in congestive heart failure
Decreased
84
Cell cycle: cell has stopped dividing
G0
85
INR to prevent deep vein thrombosis
2 to 3
86
Neutrophil stays in the PB for how long
7 hours
87
PT and APTT specimen must be centrifuged within
1 hour
88
Total area of Levy chamber
9 mm^2
89
Adjust Drabkin's reagent if WBC count is
>20 x 10^6/L
90
Anticoagulant for OFT
Heparin
91
alpha-2 beta-2 6 glucose to lysine
Hemoglobin C
92
Test: (+) Holly leaf appearance
Metabisulfite test
93
Phagocytic cell (s) containing lysozyme
Neutrophils and monocytes
94
2 cells pass thru orifice, counted as 1
Coincidence
95
Effect of platelet satellitism on platelet count
False-decrease
96
Size threshold range for platelets
2-20 fL
97
Plasma thromboplastin component
Factor IX
98
MK with MODERATE condensed chromatin
MK-II
99
Solid tumor counterpart of stem cell leukemia
Lymphoma, undifferentiated
100
Solid plasma tumor counterpart of plasma cell leukemia
Myeloma
101
PPE for enteric isolation
Gloves, gown
102
Granule absent in Hermansky-Pudlak
Dense granules
103
Effect of megakaryocyte fragments in WBC count
False-increase
104
Effect of old specimen on MCV
False-increase
105
Effect of old specimen on platelet count
False-decrease
106
Effect of old specimen on MPV
False-increase
107
Effect of cold agglutinins on MCHC
False-increase
108
Effect of lipemia on hemoglobin determination
False-increase
109
Individual globules of immunoglobulins in plasma cells
Russell bodies
110
M:E ratio of 10:1 is often seen in
Leukemia
111
Severe increase in abnormal erythrocyte in MF
3+
112
What are anulocytes
RBCs with thin rim of hemoglobin
113
During 1st hour, MPV of EDTA specimen increases by
20%