Flashcards in Clinical Cytogenetics Deck (27):
fundamental packaging unit of DNA
'petite,' short arm
cultured cells arrested in metaphase (treated with colchicine)
centromere in center
short and long arm
have 'very tiny short arms'
alphoid DNA repeat unit
beta satellite outer, tandem hexanucleotide repeats (5-TTAGGG-3)
what stage does in cell cycle does DNA replication occur?
what happens in G2?
cell prepares to undergo mitosis
how many double helix are there beginning of S1?
when does a cell have two double helices?
end of S
when does recombination occur
meiosis 1, prophase 1
when does reproduction arrest in female meiosis?
what is a disadvantage to FISH and SKY methods?
need living cells unlike Array CGH
when can nondisjunction occur
in meiosis 1 or 2
what karyotype is associated with turner
what karyotype is associated with klinefelter
what karyotype is associated with the most common chrom. abnormality?
what is the normal karyotype
down syndrome karyotype
patau syndrome karyotype
edwards syndrome karyotype
acrosonian, fusion of short arms
exchange of either/or centric and acentric