clinical heme: dr. lucas

Question 1

AIHA: intravascular anemia leads to ___ (excretion)

Answer 1

muddy colored urine

Question 2

AIHA: extravascular anemia leads to ___ (excretion)

Answer 2

black stool-melena

Question 3

what is thrombocytopenia? and what causes it?

Answer 3

decreased platelet production: Rx: antibiotics, diuretics, arthritis meds, ASA, plavix, or microangiopathy,

Question 4

primary hemostasis is:

Answer 4

1st line of defense: platelets and endothelial cells

Question 5

secondary hemostasis is:

Answer 5

clotting/coag factors
fibrin mesh clot
finbrinolytic cleaning system/setting boundaries for clot

Question 6

test for primary hemostasis

Answer 6

platelet function assay/aggregation study = clotting test

Question 7

disease that is secondary hemostasis

Answer 7

Von Willebrand (TTP):

Question 8

Von Willebrand is ___ ____ inheritance and blood type ___

Answer 8

autosomal dominant
blood type O
***increased by estrogen, thyroid, inflammation, exercise

Question 9

FSP

Answer 9

fibrin split product: platelet abnorm/bleeding

Question 10

hemopheliacs

Answer 10

X-linked

Question 11

decreased characteristics of Liver Dz

Answer 11

clotting factors
ptn C and S
fibrinogen

Question 12

increased characteristics of liver dz

Answer 12

FSP
hypersplenism
fibrinolysis

Question 13

which clotting factors does the LIVER make?

Answer 13

ALL except 8&5

Question 14

external thrombosis risk factors

Answer 14

prior occurrence, surgery, immobilization, myeloproliferative Dz, antiphospholipid Ab Syndrome

Question 15

how to recognize antiphospholipid Ab syndrome?

Answer 15

multiple miscarriages late in preg

Question 16

inherited risk factors for thrombosis

Answer 16

antithrombin 3/ptn C/ptn S deficiency, favtor 5 leiden

Question 17

when/who to test for thrombosis?

Answer 17

NOT ACUTE