Clinical Lab Flashcards
(21 cards)
Specificity
Probability of (-) result in a person without the disease. true neg/(true neg + false pos)
Sensitivity
Prababiliy of a (+) result in a person with the disease. Fewer false negatives=higher sensitivity. True pos/(true pos + true neg)
False positive
Pt who does not have the disease tests positive for it
False Negative
Pt who does not have the disease tests negative for it
Predictive value
Population with a positive test. Influenced by prevalence
prevalence
of existing cases in population
Incidence
of new cases in population over a unit of time
Accuracy
How close to measured value is the true value
Precision
How reproducible is the result with repeating the test
Red Cap
Glass: nothing. Plastic: clot activator to give serum product. Used in serology, blood bank, chemistry tests
2 step post analytic review
Analytic correctness, Clinical significance
Parametric Methods
Used in Gaussian distribution value
Screening tests
High sensitivity. Typically for diseases with effective treatments. Disease must have have enough prevalence
Confirmatory tests
Require high specificity to be confident in diagnosis
Red/Gray cap
No anticoagulant but has clot activator and gell for separating cells from serum. Used in serology and chemistry tests
Light blue cap
Citrate anticoagulant. Used in coagulation tests
Purple Cap
EDTA anticoagulation. CBC/ammonia tests
Green cap
Heparin anticoagulant. Blood gases/chemistry tests
Gray cap
Fluoride with Oxalate anticoagulant. Glucose (antiglycolytic agent)/ lactate test
Yellow cap
Acid-citrate-dextrose (ACD) or sodium polyanethol sulfonate (SPS). Blood bank studies (ACD)/Blood cultures (SPS
Dark Blue Cap
Specially treated stopper only. Trace elements/nutritional studies/toxicology
