Clinical Psychopharmacology Flashcards Preview

Pharmacology > Clinical Psychopharmacology > Flashcards

Flashcards in Clinical Psychopharmacology Deck (36):
1

Phenothiazines (aliphatic side chain)

Chlorpromazine

2

Phenothiazines (piperidine side chain)

Thioridazine, pipothiazine

3

Butyrophenones

Haloperidol

4

Thixanthenes

Flupenthixol, zuclopenthixol

5

Diphenylbutylpiperidines

Pimozide

6

Dibenzodiazepines

Clozapine

7

Benzoxasoles

Risperidone

8

Thienobenzodiazepines

Olanzapine

9

Dibenzothiazepines

Quetiapine

10

Substituted benzamides

Sulpride, amisulpride

11

Arylpiperidylindole

Aripiprazole

12

Reboxetine

Noradrenaline reuptake inhibitor (NaRI)

13

St. John wort

Weak MAO/SNRI/SSRI

14

Trazodone

Weak antagonist and SARI (serotonin antagonist and reuptake inhibitor)

15

Maclobemide

Reversible MAO-A

16

Agomelatine

Melatonergic agonist (MT1 and MT2 receptors) and 5HT 2C

17

Bupropion

Norepinephrine-dopamine reuptake inhibitor NDRI and nicotine’s acetylcholine receptor antagonist

18

Donepezil

Reversible acetylcholinesterase inhibitor

19

Galantamine

Reversible acetylcholinesterase inhibitor and bind allosterically to the nicotinic acetylcholine receptor

20

Tacrine

Reversible acetylcholinesterase inhibitor

21

Memantine

NMDA antagonist

22

Rivastigmine

Reversible acetylcholinesterase inhibitor and butyrylcholinesterase inhibitor

23

Valproate

GABA agonist and NMDA antagonist

24

Gabapentin

GABA agonist

25

Topiramate

GABA agonist, NMDA antagonist and Na channel stabiliser

26

Carbamazepine

Stabilises Na channels

27

Phenytoin

Stabilises Na channels

28

Lamotrigine

NMDA antagonist and stabilises Na channels

29

Pregabalin

Potent ligand for the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system

30

Benzodiazepines

GABA-A agonist

31

Z-drugs

GABA-A agonist

32

Buspirone

5HT1A partial agonist

33

Amisulpride

D2/D3 selective antagonist D2=D3>D4

34

Olanzapine

Dopamine and 5HT2 antagonism

35

Aripiprazole

Partial agonist at 5HT1A and D2, and 5HT2A antagonist

36

Clozapine

High affinity for D4, also 5HT1A partial agonist and 5HT2 antagonist