Clinical Psychopharmacology Flashcards Preview

Pharmacology > Clinical Psychopharmacology > Flashcards

Flashcards in Clinical Psychopharmacology Deck (51):
1

Phenothiazines (aliphatic side chain)

Chlorpromazine

2

Phenothiazines (piperidine side chain)

Thioridazine, pipothiazine

3

Butyrophenones

Haloperidol

4

Thixanthenes

Flupenthixol, zuclopenthixol

5

Diphenylbutylpiperidines

Pimozide

6

Dibenzodiazepines

Clozapine

7

Benzoxasoles

Risperidone

8

Thienobenzodiazepines

Olanzapine

9

Dibenzothiazepines

Quetiapine

10

Substituted benzamides

Sulpride, amisulpride

11

Arylpiperidylindole

Aripiprazole

12

Reboxetine

Noradrenaline reuptake inhibitor (NaRI)

13

St. John wort

Weak MAO/SNRI/SSRI

14

Trazodone

Weak antagonist and SARI (serotonin antagonist and reuptake inhibitor)

15

Maclobemide

Reversible MAO-A

16

Agomelatine

Melatonergic agonist (MT1 and MT2 receptors) and 5HT 2C

17

Bupropion

Norepinephrine-dopamine reuptake inhibitor NDRI and nicotine’s acetylcholine receptor antagonist

18

Donepezil

Reversible acetylcholinesterase inhibitor

19

Galantamine

Reversible acetylcholinesterase inhibitor and bind allosterically to the nicotinic acetylcholine receptor

20

Tacrine

Reversible acetylcholinesterase inhibitor

21

Memantine

Non-competitative NMDA antagonist

22

Rivastigmine

Reversible acetylcholinesterase inhibitor and butyrylcholinesterase inhibitor

23

Valproate

GABA agonist and NMDA antagonist

24

Gabapentin

GABA agonist

25

Topiramate

GABA agonist, NMDA antagonist and Na channel stabiliser

26

Carbamazepine

Stabilises Na channels

27

Phenytoin

Stabilises Na channels

28

Lamotrigine

NMDA antagonist and stabilises Na channels

29

Pregabalin

Potent ligand for the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system

30

Benzodiazepines

GABA-A agonist

31

Z-drugs

GABA-A agonist

32

Buspirone

5HT1A partial agonist

33

Amisulpride

D2/D3 selective antagonist D2=D3>D4

34

Olanzapine

Dopamine and 5HT2 antagonism

35

Aripiprazole

Partial agonist at 5HT1A and D2, and 5HT2A antagonist

36

Clozapine

High affinity for D4, also 5HT1A partial agonist and 5HT2 antagonist

37

Ketamine

NMDA antagonist

38

Phencyclidine

NMDA antagonist

39

Lofexedine

Alpha 2 agonist

40

Clonidine

Alpha 2 agonist

41

Buprenorphine

Partial agonist at the mu opioid receptor

42

Naloxone and naltrexone

Pure opioid antagonist

43

Atomoxetine

Noradrenaline reuptake inhibitor

44

Varenicline (champix)

Nicotinic receptor partial agonist

45

Disulfiram

Binds irreversibly to aldehyde dehydrogenase

46

Acamprosate

Metabotropic glutamate receptor antagonist and GABA agonist

47

Selegiline

Selective irreversible inhibition of MAO-B, also inhibits MAO-A at higher dose

48

Sidenafil

Inhibits c-GMP specific phosphodiesterase type 5 (PDE5)

49

Methadone

Full agonist at the µ-opioid receptor, but also has some affinity for the NMDA ionotropic glutamate receptor.

50

Methadone

Full agonist at the µ-opioid receptor, but also has some affinity for the NMDA ionotropic glutamate receptor.

51

Procyclidine

Procyclidine is an anticholinergic drug principally used for the treatment of drug-induced parkinsonism, akathisia and acute dystonia; Parkinson disease; and idiopathic or secondary dystonia.