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Flashcards in CNS Part 2 Deck (25)
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1

It is caused by invasion of the organism, Treponema pallidum into the CNS

neurosyphilis

2

4 types of neurosyphilis

asymptomatic, meningovascular, tabes dorsalis, and general paresis.

3

characterized by perivascular inflammation in the brain.

Meningovascular syphilis

4

result of widespread parenchymal invasion by spirochetes and resultant inflammatory changes that cause individual brain cell death and brain atrophy

paretic syphilis

5

result of damage to the sensory nerves in dorsal roots, producing ataxia and loss of pain sensation and proprioception.

Tabes dorsalis

6

The most common presentation of meningovascular syphilis

stroke syndrome in a relatively young adult, involving the middle cerebral artery or the branches of the basilar artery.

7

Stroke syndrome caused by meinigovascular syphilis involves which 2 cerebral arteries?

middle cerebral artery or the branches of the basilar artery

8

Meningovascular syphilis frequently involves ... and therefore may result in...

cranial nerve palsies

9

occurs approximately 20 to 30 years after the initial exposure to T. pallidum as a result of progressive meningoencephalitis with resultant

paretic syphilis

10

tissue invasion with spirochetes, chronic perivascular and meningeal inflammatory changes and meningeal fibrosis.

paretic syphilis

11

slowly progressive degenerative form of syphilis involving the posterior columns (demyelination) and posterior roots (inflammatory change with fibrosis) of the spinal cord

tabes dorsalis

12

Neurosyphilis often results in the formation of meningeal granulomas known as called

gummas

13

is a well-circumscribed mass of granulation tissue resulting from a cell-mediated immune response to Treponema

gumma

14

Several hours following the treatment of early stages of syphilis, individuals may undergo a febrile reaction called a

Jarisch-Herxheimer reaction

15

Progressive multifocal leukoencephalopathy (PML) is a condition that is caused by the

JC virus, a member of the polyomavirus family

16

rare demyelinating disease which is progressive and results in the loss of oligodendrocytes.

Progressive multifocal leukoencephalopathy (PML)

17

a rare complication of measles (rubeola) that can develop from 1 to 20+ years after the initial measles infection.

Subacute sclerosing panencephalitis

18

The only change in the CSF profile is a marked elevation in what specially ordered CSF immunoglobulin?

Rubeola IgG Antibody

19

After a period of viremia, this virus becomes neurotropic and produces destruction of the motor neurons in the anterior horn and brainstem.

polio

20

Inclusion bodies within neurons, called Negri bodies, are 100% diagnostic for ... but are found in only approximately 20% of rabies cases.

rabies infection

21

The frequency of ADC increases with advancing effects of HIV disease, particularly as ... cell counts decrease

CD4+

22

MRI of a patient with...showing cortical atrophy and marked ventricular enlargement

AIDS dementia

23

unusual yet often fatal encephalopathy characterized by fever, vomiting, fatty infiltration of the liver and swelling of the kidneys and brain.

Reye's Syndrome

24

is an infection of the brain due to infection by an unconventional transmissible agent known as a prion.

Spongiform encephalopathy

25

Two main examples of spongiform encephalopathy

Kuru and Creutzfeldt-Jakob disease (CJD).