Flashcards in Coagulopathies Deck (18)
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1
Differential for platelet / bleeding disorders (PVC Pipes0
PVC Pipes
Platelets
VWD
Clotting factors
Pipes
2
Platelet Probs
Not enough (<50,000) from decreased production or increased destruction / sequestration
Not working due to aspirin, NSAIDs, Uremia, Genetic
3
vWD
Type I most common
Decreased platelet adhesion and lack of stabilized factor VIII
4
Clotting Factors
Most common - VIII and IX
Vitamin K deficiency (for VII, IX, X, II, I)
Liver disease
Presence of factor inhibitors
5
Pipes
Vasculitis
Scurvy
Ehlers Danlos
Steroids
Sepsis
Drugs
6
Assesses extrinsic pathway
PT / INR
7
Assesses intrinsic pathway
PTT
8
Most common congenital coagulopathy
Von Willebrand Disease
9
Bleeding in nasal, sinus vagina, GI mucous membranes. Common cause of menorrhagia. Can have increased PTT. Abnormal PFA
vWD
10
Second most common coagulopathy after vWD. The most severe bleeding disorder
Hemophilia A
X-Linked Recessive
11
Severe - epistaxis, intracranial bleeding, soft tissue and gingiva bleeding, Hematemesis, Melena, etc.
Less severe may have excessive bleeding following surgery
Hemophilia A (VIII Deficiency)
12
Coag tests in Hem A (VIII Deficiency)
Normal PT, Increased PTT
13
Most common acquired coagulopathy
Vitamin K deficiency
14
Typical patient of this disorder is postoperative, not eating well, receiving broad spectrum antibiotics
Vitamin K deficiency
15
Vitamin K factors
VII, IX, X, II, I
16
Virchow's Triad
Hypercoagulable State
Vascular Injury
Stasis
17
Acquired hyper coagulable states
Malignancy (Trousseau's)
Pregnancy
Nephrotic Syndrome
Estrogen meds
Immobilization
Myeloproliferative Diseases
18
