Coating, Capsules, Water Flashcards
why is the specific surface of the cores important?
it control the coating thickness
why is endusting important?
rough surface leads to agglomeration
low porosity ?
it is not wanted, it reduces the specific surface
relevant of the uniform film thickness
very important for modified, pulsatile, time controlled and active coating
Polymer solution?
viscosity depends on centration
very good solvent srong interaction, used of rather porly solvating solvent
what’s the minimum film forming tempertarue?
temp at which a polymer dispersion gives a crack-free fidrung drying, film forming occur above the MFT
hard and soft capsules?
hard capusles: shells consisting of 2 prefabricated cylinderical sactions
Soft capules: thicker shels than those of HC, consist of a single part
purified water and water for injection
prepation of medicines (PW)
WFI: prepartion of parenteral used
water treament?
ion exchanger( not enough itself to get purified water
membrane filteration method, electro deionization
distillation
Rheology?
deformtion of the body under external stresses
dynamic and kinematic viscosity?
dynamic: describe the inner friction of the fluid
Kinematic: is the dynamic viscosity/density
Reynolds number
mesurement of viscosity, the ratio of interial forces to viscous forces within a fluid
When do you used WFI in bulk and sterilised water for injection
WFI in bulk, when water is ued as a vehicle and sterilised water for injection for desolving your substance for the prepartion of the parenteral preparation.
What’ the main different bewettn WFI in bulk and sterilised WFI
sterilised WFI is WFI in bulk which is additional heat sterilised and stored in a container
