coccidia 1

Question 1

Coccidia belong to which phylum?

Answer 1

apicomplexia

Question 2

what are coccidia types ?

Answer 2

intestinal coccidia - blood and tissue coccidia

Question 3

give what parasites are belong to the intestinal coccidia

Answer 3

cryptosporidium
isospora
cyclospora

Question 4

give some parasites that belong to the blood & tissue coccidia

Answer 4

plasmodium
toxoplasm
babesia
sarcosystis

Question 5

what are the general/in common characteristics of the intestinal coccidia parasites?

Answer 5

1-opportunistic in immunocompromized people
2-life cycle in one host
3-live in intestinal epithelial cells of the host
4-thick walled oocyst in feces
5-fecal-oral route transmission

Question 6

what cryptospordium can cause(symptom)

Answer 6

• self limiting diarrhia in healthy individuals
• chronic persistent life threatening diarrhia in HIV individuals

Question 7

C. parvum infect only humans?

Answer 7

no wide range of animals ( fish -humans)

Question 8

which C. infect animals besides humans?

Answer 8

C.parvum

Question 8

what C. infect only humans ?

Answer 8

C.hominis

Question 9

what are other species of cryptospordium you know?

Answer 9

C. felis-canis-muris-meleagridis can also be found

Question 10

how many hosts for C. parvum ?

Answer 10

one host animal or human

Question 10

what is the morphology of c.parvum?

Answer 10

oocyts

Question 11

what is the protection form of c. parvum?

Answer 11

sporulated oocytes -infective stage

Question 11

what is the active form of c.parvum?

Answer 11

sporozoits

Question 12

what is self limiting dirria?

Answer 12

means restricted frequently without drugs

Question 13

what are the types of sporozoits based on location?

Answer 13

inside/outside sporocyst

Question 14

what is the sexual form in c.barvum life cycle ?

Answer 14

meront ll

Question 14

which type of sporozoit does C.barvum have?

Answer 14

it doesnt have sporocyst in first place

Question 15

what is the asexual form of C.barvum?

Answer 15

meront l

Question 16

what is excystation?

Answer 16

come out of the inside of the cyst

Question 17

what virulance means?

Answer 17

when enzymes balance change it become more valunarble to get c. as in AIDS

Question 18

what is the dignosis form of C.

Answer 18

oocyte found in feces

Question 19

what is the structure of oocyst in cryptosporidium?

Answer 19

cell wall and 4 sporozoites inside with no sporocyst

Question 20

what is the structure of sporozoites?

Answer 20

crescentic structure-pointed anterior end - blunt posterior end with nucleus

Question 21

what are the types of oocytes?

Answer 21

thick walled /thin walled

Question 22

explain the structure of thick wall oocyte?

Answer 22

2 electrodense walls outer wall is thick and coarse inner wall is granular and has suture at one pole between them is electroluscent middle zone

Question 23

thin wall oocyte structure?

Answer 23

has only sinle wall

Question 24

oocyt walls are so resistant .what some disinfectants they might be resistant to?

Answer 24

chlorination -heat and dont stain by iodine and are fast stain in nature

Question 25

name th parasite in each stage of its life cycle in C.

Answer 25

1-sporulated oocyst(infective stage) 2-sporozoite(by excystation after ingesting it will invade the intestinal epithelial cells of the host) sprozoites differentiate into trophozoites 3-trophozoite(feeding and growing stage its when the parasite forms) **inside trophzoites reproduction happens meront l = asexual = 8 merozoites(infect other cells ) *outside trophozoite = meront ll = sexual (merozoites will be undifferentiated gametes then differentiate into macro and microgametes and fuse to form zygote)** 4- zygote will be thick or thinn wall oocyst thick =exit the host thin = repeat the cycle inside the host

Question 26

what is the last role in C. thin wall oocyst life cycle ?

Answer 26

causes autoinfection through contaminated fingers

Question 26

what is the last role of C. thick walled oocyst?

Answer 26

excreted in feces and infect other people through feces

Question 27

what is the mode of transmissiom of C.?

Answer 27

Feco-oral route - ingestion of thick wall oocyst

Question 28

how the excystation of C. sporozoites start?

Answer 28

suture on the inner wall of oocyst dissolve and release 4 sporozoites into the intestines

Question 29

what factors might help in the excystation of the C. sporozoites?

Answer 29

bile salts like pancreatic enzymes

Question 30

where all the stages of C. development in human occur?

Answer 30

parasitophorous vacuole on brush border epithelium of the small intestines

Question 31

after excystation where C. sporozoites will stay/invade ?

Answer 31

on brush border epithelium inside parasitophorous vacuole ion the small intestines

Question 32

C. how meront l is formed?

Answer 32

from the first asexual /schizogony reproduction of trophozoites

Question 33

what the first thing happen to C. sporozoites after reaching the small intestines ?

Answer 33

differentiate into trophozoites to form meront l

Question 34

what C. meront l will produce asexually /schizogeny ?

Answer 34

8 merozoites then meront ll

Question 35

after C. gamtogony what we have ?

Answer 35

each microgamete give 16 microgametes each macrogamete give 1 macrogamete

Question 36

whats the next step for zygote of C. ?

Answer 36

80% will be thick wall oocyst 20 % will be thin wall oocyst

Question 37

how long does the C. life cycle inside the human takes?/prepatent period

Answer 37

4-22 days

Question 38

LIST STAGES OF SPOROZOITES DEVELOPMENT INSIDE HUMAN

Answer 38

1-excystation 2-invasion 3-schizogony/asexual(3stages) 4-gamatogony/excystation 5-sporogony/zygote formation 6- final excystation

Question 39

what are virulence factors of C.?

Answer 39

1-membrane aminopeptidase 2-cysteine proteas 3-a heamolysin 4-lectin/thromboplastin related adhestion molecule

Question 40

clinical manefestation of C.?

Answer 40

1- self-limiting dirrhoeal illness(in immuncompetent person mostly children) 2-sever prolonged life threatening dirrhoeal( AIDS)

Question 41

what is the clinical manifestation for AIDS person in C. ?

Answer 41

intestinal =same symptoms and might led to death extraintestinal= -respiratory problems -hepatitis -pancreatitis -cholecystitis

Question 42

which people C. mostly infect?

Answer 42

children and AIDS person

Question 43

prevention of C.

Answer 43

-water filteration -swimming pools-pasteurization - washing hands