Cognitive Impairment PSYCH Flashcards
Name & describe the 3 attentional networks
Alerting
• Thalamic
• Frontal
• Parietal
Orientating
• Frontal eye fields
• Temporoparietal activation
Executive
• Anterior cingulate
• DLPFC
4 types of memory
- describe
- location in brain
- Neurotransmitter
Executive
• Anterior cingulate
• DLPFC
Semantic
• General knowledge
• Temporal lobe
• Glutamate
Procedural
• Procedures (explicit or implicit)
• Cerebellum 7 supplementary motor area
• Glutamate
Working
• Active memory
• Prefrontal cortex
• NE, S & D
Which drug used for Alz
Donepezil
Which drug used for ADD or TBI
Methylphenidate
Which drug for ADHD
Atomoxetine
Donepezil
- class
- Use
- Metabolism (half life)
- Interactions
- SE
Class
- AchE
Use
- Alz
Metabolism
- Live and long half-life
Interactions
• Careful of drugs that induce hepatic metabolism (phenobarbital, phenytoin, carbamazepine, dexamethasone, rifampin)
SE - Cholinergic • Nausea • Vomiting • Sinus bradycardia • AV block • Monitor LFT
Methylphenidate
- class
- Use
- Metabolism (organ)
- Interactions
- SE
Class
• CNS stimulant
• Similar to amphetamine
• Blocks reuptake of Ne & D
Use
• ADD
• TBI
Metabolism
• Liver
Interactions • DON’T USE WITH MAOI • Increases action of o Barbiturates o Phenytoin o TCA o Anticholinergic o Meperidine (analgesic)
SE
• Nervousness
• Insomnia
• Dependence/abuse potential
Atomoxetine
- class
- Use
- Metabolism (organ)
- Interactions
- SE
Class
• Selective NE reuptake Inhibitor
Use
• ADHD
Metabolism
• Liver
Interactions
• CYP2D6 inhibitors (quinidine)
Chlinesterase inhibitor used for Parkinson’s disease
Rivastigmine
Stimulant for TBI
Dextroamphetamine
NMDA receptor antagonists
o Amantadine
o Memantine
Dopamibe receptor agonist
o Ropinirole
o Enhance D release
Drug used for narcolepsy
o Modafinil (narcolepsy)
