Cognitive Neuroscience methods Flashcards

1
Q

main characteristics about a cognitive model

A

Specific and realistic
Parsimonious (simple)
falsifiable
linked to knowledge of the brain

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2
Q

Important aspects for the study of behaviour

A

accuracy and reaction time involved in models

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3
Q

electrodes that pick up signals from a neuron

A

single cell recordings

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4
Q

behaviour can tell us

A

difficulty of the problem

influence of extraneous factors

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5
Q

behaviour study requires

A

control over inputs and analysis of the outputs

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6
Q

amount of time it takes for an input to generate a response

A

reaction time

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7
Q

erros that reflect task-related and non-task related issues

A

accuracy

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8
Q

A good cognitive model

A

can be reduced to parts of the brain

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9
Q

consequences from spontaneous neural activity

A

we need a dramatic increase in order to link stimulation to function

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10
Q

map parts of the eye to parts of the brain is called

A

retinatopic

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11
Q

map of frequencies to the brain is called

A

tonotopic

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12
Q

tracing from cell body to terminal is

A

anterograde

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13
Q

tracing from terminal to cell body is

A

retrograde

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14
Q

tracing allows to

A

know where electrons come from

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15
Q

lesion to temporal lobes in animals cause

A

Kluver bucy syndrome

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16
Q

difficulties reaching objects is caused by

A

lesions in parietal lobes

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17
Q

method that allows to study brains lacking an area without surgery

A

genetic manipulation

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18
Q

Computerized Axial Tomography (CT) relies on which principle?

A

different tissues absorb radiation at different rates

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19
Q

Structural Magnetic Resonance Imaging (sMRI) relies on

A

magnetic properties of tissues on the brain. waves that get back are called resonance

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20
Q

unit for brain volume

A

voxels: volumetric pixels

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21
Q

Advantages of sMRI for lesion tracing

A

boundary, size and extent of injury

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22
Q

process of stretching the brain to fit the general template

A

spatial normalization

23
Q

reason why we need normalization

A

brains have different sizes

24
Q

Difussion tensor imaging (DTI) principle

A

water moves more readily along the white matter tract

25
Elentroencephalography (EEG) method
uses a cap of electrodes that pick up electrical signals from brain
26
event-related potentials (ERP) are computed by
averaging several trials
27
average of ERP is needed because
it reduces noise and characterizes the real peaks associated to mental processes
28
funtional method that uses radioactive isotopes and measures the emission of gamma rays
Positron Emission Tomography Imaging (PET)
29
PET is used for which diseases
cancer, schizofrenia and alzheimer
30
Funtional Magnetic Resonance Imaging (fMRI) principle
magnetic properties of oxygen allows to track blood oxygenated level dependent (BOLD) signals
31
Echo Planar Imaging (EPI) is
slice the brain and repeat readings
32
type of imaging that answers questions about brain dynamics
functional imaging
33
dark areas on CT are
ventricles
34
advantages of fMRI over CT
better resolution and safer
35
limitations of MRI
cannot be used if people have ferrous metals in their body
36
mehtods that looks at patients with common areas of impairment and see areas of injury
Lesion overlap technique
37
template used to compare brains was crated by
Montreal National Institute
38
the ratio of water moving in one direction against other directions
fractional anisotropy
39
DTI is used in
injuries, trauma, mutiple sclerosis and other cases where white matter is damaged
40
limitation of DTI
only looks at white matter | subjects have to be stable
41
method with greatest temporal resolution
EEG
42
limitations of EEg
bad spatial resolution
43
advantages of PET
good spatial resolution, it can isolate parts of the frontal lobe
44
principle that predicts in the changes of blood flow in the brain
hemodynamic response
45
principle that says the more neural activity requires more oxygenated blood
neurovascular coupling
46
limitation of fMRI
very bad temporal resolution (about 6 seconds) | not every region has the same hemodynamic response
47
method with worst temporal resolution
PET
48
define subtraction method
take sample of the experimental condition, then the control condition and look at differences in activation
49
Transcranial magnetic stimulation (TMS) principle
magnetic pulse introduces a electrical current that changes neural activity
50
limitations of TMS
very much detail needed to stimulate right area
51
relation between stimulation and activation is
proportional in time and activity (higher frequency excites while ow frequency disrupts)
52
Optical imaging principle
shine laser to the brain and pick up how light scatters or is absorbed
53
method that shows neurotransmitters levels
optical imaging