Common Infections Flashcards

(31 cards)

1
Q

Infections that can result in a sepsis response?

A

UTI

respiratory tract infections

Lemièrre’s syndrome - URTI

pneumonia - LRTI

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2
Q

Symptoms of UTI?

A

Symptoms may be specific.
(painful micturation (dysuria), urinary frequency, urinary urgency, haematuria,
lower abdominal/loin pain).

or may be vague systemic symptoms.
(confusion, diarrhoea, vomiting).
- Often in older pt

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3
Q

Signs of urosepsis?

A
  • Signs - fever, abdominal tenderness, cloudy urine.
  • Simple uncomplicated.
  • Complicated (i.e. pyelonephritis or prostatitis).
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4
Q

How do you diagnose UTI?

A
  • Dipstick showing nitrites or leucocytes.
  • Diagnosis supported by examination of urine.
  • Pus cells help differentiate between asymptomatic bacteriuria and infection.
  • Bacterial growth: usually Gram negative e.g. Escherichia coli, Klebsiella,
    Proteus; less commonly Enterococcus spp.
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5
Q

Bacteria associated with a UTI?

A

usually Gram negative

e.g. Escherichia coli, Klebsiella,
Proteus;

less commonly Enterococcus spp.

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6
Q

Upper respiratory tract infections include what anatomical features?

A

nasal cavity

pharynx

larynx

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7
Q

Lower respiratory tract infections include what anatomical features?

A

trachea

primary bronchi

lungs

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8
Q

aetiology of URTI?

A

VIRAL - most common

(rhinovirus, enterovirus, adenovirus)

  • EBV or bacterial - Streptococci (Group A, C, G) - not as common
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9
Q

typical causes of URTI?

A

Common cold

laryngitis

pharyngitis

tonsillitis

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10
Q

oral manifestation of URTI?

A

pus in oral cavity

tonsillar swelling - airway obstruction

peritonsillar abscess

usually polymicrobial eitology

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11
Q

who usually gets Lemièrre’s syndrome?

A

fit healthy young pts

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12
Q

symtpms of Lemièrre’s syndrome?

A

sore throat/tonsillitis leading to sepsis

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13
Q

what bacteria causes Lemièrre’s syndrome?

A

fusobacterium necrophorum

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14
Q

pathophysiology of Lemièrre’s syndrome?

A

peritonsillar abscess formation, bacteraemia & thrombus
formation in neck veins (internal jugular) –> septic emboli to lungs/joints.

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15
Q

what is fusobacterium necrophorum associated with?

A

associated with periodontal disease

oral anaerobic bacteria

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16
Q

what can occur with fusobacterium necrophorum?

A

bacteraemia (spread to blood stream)

thrombus formation in the neck

send off septic emboli to lungs and joints

an example of a metastatic infection

17
Q

can Lemièrre’s syndrome be fatal?

A

YES, can be fatal, so requires a high degree of suspicion and urgent imaging.
* Rx penicillin plus clindamycin/metronidazole.

18
Q

tx of Lemièrre’s syndrome?

A

Rx penicillin plus clindamycin/metronidazole.

19
Q

examples of LRTI?

20
Q

what is pneumonia?

A
  • Infection of the parenchyma of the lung.
  • Can affect patients of all ages
21
Q

who is predisposed to pneumonia?

A

alcoholics, post influenza.

22
Q

symptoms of pneumonia?

A

productive cough (green purulent sputum), pleuritic chest pain,
shortness of breath.

23
Q

bacteria casing pneumonia?

A

s. pneumonia, gram positive

24
Q

skin and soft tissue infections causing sepsis?

25
Are complicated SSTI common?
no, rare but serious
26
example of complicated SSTI?
necrotising fasciitis
27
necrotising fasciitis symptoms?
– life-threatening, hypotension, pain ++++, may be minimal cellulitis. * Myositis/deep abscess – swinging fevers, pain. usually septic call consultant asap
28
tx for necrotising fasciitis?
broad spectrum abx - clindamycin, penicillin, benzylpenicillin. surgical debridement
29
most common pathogens for SSTI?
Most common pathogens: o Staphylococcus aureus (consider MRSA in patients previously colonised/ lots of hospital exposure) - wound infections o Beta-haemolytic streptococci (esp. Group A) - nec remember group A strep for nec usually not polymicrobial
30
Biggest bacterial culprit for wound infections?
Staph. aureus
31
what to consider if pot has staphylococcus aureus infection (SSTI)?
consider MRSA in patients previously colonised/ lots of hospital exposure