Cranial nerve disorders Flashcards
(43 cards)
nerves in relation to eyes?
3,4,6,
SO muscle of the eye, innervated by what nerve?
CNIV - trochlear
in an ddownward movement
LR muscle of the eye, innervated by what nerve?
CNVI - abducens
lateral movement
double vision looking down indicates what?
CNIV - trochlear
4th nerve palsy following head injury
causes IVth nerve palsy?
congenital
idiopathic
severe head trauma
microvascular disease (HT, DM, atherosclerosis)
tumour
aneurysm
MS
MS?
CNS, white matter demyelination disorder
4th nerve ipsilateral of contralateral?
condralateral
ptosis?
drooping eyelid
dilated pupil/occulomotor abnormalities, what nerve is affected?
3rd nerve palsy
eye down and out, complete ptsosis and dilated pupil
causes of 3rd nerve palsy?
microvascular, infact of teh centre of the 3rd nerve
- can be pupil sparing
posterior aneurysm
- pupil involving, pt about to rupture an aneurysm
cavernous sinus
- tumour
- sinus thrombosis
meningeal
- aneurysm (posterior commuivcatung artery aneurysm)
- infective or malignant meningitus/inflammation
neuromuscular junction - myasthenia
what nerve innervates the levator palpabre superioris?
occulomotor CN3
syndrome associated with CN3 palsy?
horner’s syndrome
symtoms of horner’s syndrome?
constricted pupil
small ptsosis, couple milimetreds drop in eyelid. droopy eyelid
fatuigable CN3 palsy?
myasthenia gravis
sympatheuc muller’s muscle? (CNIII)
muscle helps rasie the upper eyelid
myasthenia gravis? (CNIII)
Myasthenia gravis is a rare long-term condition that causes muscle weakness.
autoimmune disorder, antibodies against acetyl nicotinic acetylcholione receptor
It most commonly affects the muscles that control the eyes and eyelids, facial expressions, chewing, swallowing and speaking. But it can affect most parts of the body.
It can affect people of any age, typically starting in women under 40 and men over 60
causes of horners syndrome? (CNIII)
Injury
- Damage to the carotid artery, the main artery to the brain
Injury to the brachial plexus, the nerves at the base of the neck
Birth trauma, such as during a difficult birth
Accidental injury
Tumors
- Tumors at the top of the lung
Tumors between the lungs and neck
Neuroblastoma, a childhood cancer of the nerve tissues
Other conditions
Migraine or cluster headaches Stroke Spinal cord injury Infection in the top of the lung, between the lungs, and neck Surgical complications
Congenital or hereditary
Horner syndrome can be present at birth, or it can be inherited
Idiopathic
Sometimes no cause can be found. This is called idiopathic Horner syndrome.
types of MG?
pure ocular MG
gernalised mg
- Extra-ocular
- bulborespiratory muscles
- limbs
what is associated with MG?
thymoma and thymic hyperplasia
tx for MG?
acetylcholineesterase inhibitirs (used to wake up form GA)
immunosuppression
- steroids
- IV immunoglobulin, plasma exchange
- Azathioprine, cyclosporin, cyclophosphamide, methotrexate
examples of acetylychonesterase inhibitirs?
pyridostigimine, neostigmine
casues of worsening MG?
- Infection
– Drugs, aminoglycosides, quinolones, quinine
- 32 year-old 2/7 pain behind ear
- Awoke right facial paralysis –near complete
- Noises sound louder on RHS
what is the problem?
bells pasly
who is most at risk of bells palsy?
More common age 30-45
– 5-fold in diabetes
– 3-fold in pregnancy esp. 3rd trimester