Community Pediatrics Flashcards

(289 cards)

1
Q

Benefits of Screens in Preschoolers

A
  • Interactive video chat and virtual story time can be beneficial
  • Can provide additional exposure to early language and literacy BUT children learn expressive language and vocabulary best through face to face dynamic interactions with caring adults
  • Learning is best when ‘co-viewed’ with a caregiver
  • Some programing / video games encourage physical activity
  • Well designed, age appropriate programing can help teach pro-social behaviour (empathy, tolerance, respect)
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2
Q

A typically-developing 1-year-old child uses screens for 1 hour per day. What do you advise parents?

A. No screen time is recommended at this age
B. He should decrease to 30 minutes per day
C. He can increase to 2 hours per day
D. Something else

A

A. No screen time is recommended at this age

No screen time children < 2yo.

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3
Q

6-year-old girl has missed 21 days of school in the last 3 months for abdominal pain that occurs in the morning and lasts a few hours before resolving. She has a normal exam and AUS as well as basic metabolic investigations are normal. Best way to manage?

A. Psychological therapy/CBT
B. Behavioral intervention with school and parents
C. Home school
D. Psychiatry referral

A

B. Behavioral intervention with school and parents.
First line therapy is Parent management training & family therapy

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4
Q

2 ½ month-old with Prader Willi Syndrome comes to your office for a weight check. Currently feeds 120mL of 20kcal/30mL formula q3h. Weight is 3.1kg. He has gained 12g/day over the last week. What do you recommend for his feeds?

A. Insert nasogastric tube for feeds
B. Decrease feed volumes because he is at risk of obesity
C. Increase caloric density of feeds
D. No change to current feeds

A

A. Insert NG tube for feeds

Prader-Willi Syndrome (PWS) is associated with neonatal hypotonia with poor suck and weight gain without nutritional support, often need more than increasing caloric density of feeds.

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5
Q

Risk of screens in preshcoolers

A
  • Interferes with face to face parent-child interactions (‘Technoference’)
  • Decreased ability to calm/self soothe with increased behaviour difficulties
  • Negative impact on social skills (greater ASD-like symptoms)
  • Heavy early screen use is associated with language delays
  • Association with delayed reading level
  • ? Increases attentional difficulties (need very high exposure)
  • Increased risk of becoming overweight
  • Increased risk of myopia (screens plus decreased time outdoors)
  • Screens before bed increases risks of sleep problems
  • Background TV
  • negatively affects language use and acquisition, attention and cognitive development
  • decreases parent-child interaction and distracts from play
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6
Q

screen time recommendations for 2 years and younger

A

NONE except for video chatting with caring adults

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7
Q

screen time recommendations for 2 - 5 year olds

A

1 hour or less per day

  • Ensure sedentary screen time is not a routine part of child care for children < 5 years
  • Maintain daily ‘screen free’ parts of the day
  • Avoid screens 1 hour before bed
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8
Q

Risks of screens in children/adolescents

A
  • Increased aggressive behavior
  • ‘Media multi-tasking’ negatively impacts learning
  • ‘Media gap’
  • Decreased opportunities for play and face to face interactions
  • Increased risk of depression and anxiety
  • Teens report feeling ‘addicted’ to their mobile devices
  • Increased risk of risky behaviours
  • Canadian study 43 % of students in Grade 4-11 engaged online with people they don’t know
  • Evidence around screens decreasing physical activity levels is mixed
  • Increases unhealthy eating
  • Impacts sleep
  • Distracted driving
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9
Q

Digital media recommendations to parents

A

4 M’s: Manage, Meaningful, Model, Monitor

  • Manage screen time
  • Encourage meaningful screen time
  • Model healthy screen time
  • Monitor for signs of problematic behavior
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10
Q

Epidemiological info on SIDS (peak age, % of infant deaths, high-risk populations)

A
  • Peaks between 2-4 months
  • Accounts for 5.8 % of all infant deaths
  • Indigenous population has a 7 x higher rate of SIDS
  • Increased incidence in infants who are male, premature or of low birth weight
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11
Q

Definiton of BRUE

A

Brief Resolved Unexplained Event (BRUE)
* Less than 1 year
* Stops breathing, has a change in muscle tone or turn pale or blue
* Lasts less than 1 minute
* Completely resolves
* NO correlation between BRUE and SIDS

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12
Q

Recommendations around Room Sharing (Baby bassinet and Caregiver’s bed in same room)

A

Lowers the risk of SIDS and should be encouraged for
the first 6 months

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13
Q

modifiable risk factors for SIDS

A
  • Placing infant on back to sleep
  • Protecting infant from exposure to tobacco, before and after birth
  • safe sleep environment: crib/bassinet with NO soft, loose bedding, in parent’s room for first 6 months
  • Breastfeeding for at least 2 months
  • Using safe sleep practices for all sleeps
  • Pacifiers reduce risk of SIDS
  • Alcohol and opiate use during pregnancy increasedrisk
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14
Q

A 2 month of term infant is not sleeping through the night. You tell the
exhausted parents that most (70-80%) infants sleep through the night
(uninterrupted sleep for 6-8 hours) by:
a) 2 months
b) 4-6 months
c) 7-9 months
d) 12 months

A

7-9 months

Many infants can sleep at least 5 hours through the night by 3-4 months

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15
Q

Amount of sleep required by age group

A
  • Healthy FT infant – 16 hours/day
  • 1 year – 14 hours/day
  • Toddler years – 12 hours/day
  • Kindergarten yrs – 10 hours/day
  • 9+ years /teens – 9 hours/day
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16
Q

A 4-year-old girl with a daily night-time routine (bath, story) often wakes up after 1 hour, cries inconsolably and is difficult to soothe. She is extremely distressed and it takes a while before she is fully awake. Most likely diagnosis?
a) behavioural insomnia of childhood
b) night terrors
c) obstructive sleep apnea
d) nightmares

A

Night terrors:
* Similar to nightmares but more dramatic
* Child is difficult to settle
* Often have physical signs (increased HR, tachypnea, sweating)
* Occur during non-REM sleep
* 2-3 hours after child has fallen asleep

Nightmares
* Peak during pre-school years
* Occur during REM sleep, second half of the night
* Can comfort the child

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17
Q

Types of Insomnia in Children

A

Delayed Sleep Phase Insomnia:
* Initiation of sleep is significantly longer than the desired bedtime
* Sleep latency is greater than 30 min
* Hard to get up in morning

Behavioural Insomnia:

1) Sleep-onset association type
* Special conditions are required of the caregivers before the child goes or returns to sleep
at night

2) Limit-setting type
* Child stalls or refuses to go to bed or return to bed and the caregiver demonstrates
unsuccessful limit setting behaviours

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18
Q

18 month old who wakes up screaming, inconsolable, parents at loss of what to do. Does not recall events.
a. Reassure
b. EEG
c. MRI
d. Refer to psych

A

Reassure - night terrors

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19
Q

what age do we start sleep training

A

wait until 6 months

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20
Q

Treatments for Positional Plagiocephaly

A
  • Re-positioning
  • ‘tummy time’ (10-15 min 3 x a day)
  • Treat torticollis with physiotherapy if present
  • Moulding therapy (helmets) if severe asymmetry (helps rate of improvement but not final outcome)
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21
Q

Positional plagiocephaly: evaluation considerations

A

Evaluate for craniosynostosis and torticollis

Pediatrician should not miss craniosynostosis which needs further investigation and consideration of surgical treatment

Torticollis needs physio

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22
Q

6 month old healthy infant with significant positional plagiocephaly. In addition to 1 hour daily of “tummy time”, you also recommend:

Consult physiotherapy
CT scan
Skull XR
Consult Neurosurgery

A

Consult physiotherapy

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23
Q

Describe effective discipline for children

A
  • Rules and commands must be clear and developmentally appropriate
  • Consequence must follow the behaviour in a timely fashion
  • Correct the behavior not the person
  • Consequence must be administered before the parent becomes angry
  • Expectation that after the punishment the child will follow the rule or complete the command
  • CONSISTENCY IS ESSENTIAL FOR EFFECTIVE DISCIPLINE
  • Effective discipline is about teaching and guiding children (not forcing them to obey)
  • Foster acceptable and appropriate behaviour in the child
  • Set developmentally realistic expectations
  • Prioritize rules (safety > harm to others > annoying behaviour)
  • Help the child learn self-discipline (healthy conscience and internal sense of responsibility)
  • Consequences must be sufficient to be considered negative without being unduly harsh
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24
Q

A 4 month old presents with a narrow elongated head and frontal bossing. What suture is most likely fused?
a) Metopic
b) Sagittal
c) Lambdoid
d) Coronal

A

Sagittal

Scaphocephaly (MC form): premature closure of sagittal suture
Associated with frontal bossing, prominent occiput, palpable keel ridge
More common in males

Trigonocephaly: premature closure of metopic suture
Narrow, triangle-shaped forehead with a prominent midline ridge resembling a keel, and superior-lateral orbital depression and hypotelorism

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25
Strategies for disciplining children
Natural consequences * Child experiences the natural consequence of his or her action Time out: * Child is removed from the situation to a quiet place * No more than 1 min per year of age (max 5 minutes) * “Away from the moment” discussions (anticipation of difficulties) NOTE: Disciplinary methods that are angry or violent are detrimental to both the parent and child’s wellbeing
26
Tips for avoiding the need to discipline children
* Catch the child being good! * Praise positive behaviour * Ignore unimportant or irrelevant behaviour * Give choices * Plan ahead
27
Physical impacts of toxic stress (ACEs) on children
* Can disrupt the development of brain architecture and other organ systems * Increases the risk for stress-related disease and cognitive impairment
28
Normal infants hit their peak of crying time at 6 weeks of age. How many hours per day of crying is considered developmentally normal at this age? a) 30 minutes b) 1 hours c) 3 hours d) 4 ½ hours
3 hours Median daily crying times: 2 week infant = 2 hours 6 weeks = 3 hours 12 wks = <1hr More crying occurs during the evening
29
Differential Diagnosis for Crying
* Infectious: Meningitis, UTI, AOM * GI: Cow’s milk protein allergy, GERD, Constipation, Hernia, Intussusception, Anal fissure * Metabolic: Hypoglycemia, Inborn errors of metabolism * Neurologic: Hydrocephalus * Trauma: Non-accidental injury, corneal abrasions, hair tourniquet
30
Red Flags for Crying
* Apneic episodes * Cyanosis * Respiratory distress * Vomiting * Bloody stools * Fever
31
Definition of infantile colic
3 + 3= 6 3 hrs of crying, 3 days a week in a <6mo old Definition of colic (Rome IV criteria): * Birth to 5 months * Recurrent and prolonged episodes of irritability, fussiness or crying that starts and stops without obvious cause * Episodes last for at least 3 hours per day, at least 3 days per week * No failure to thrive * Total daily crying greater or equal to 3 hours when measured by at least one prospectively kept 24 hour diary * Etiology is unknown * There is little evidence that dietary modification makes a difference and it should not be encouraged
32
You are working in a northern remote community when a nurse calls you into the room urgently. She was giving a child their 18 month immunization (didn’t specify which one) and the child screamed, then turned blue and had jerking movements for 20 seconds. What is your next step? Order an ECG Order a complete blood count Order an EEG Send urgently to a tertiary care centre
Order a complete breath count- breath holding spells. Iron deficiency anemia is a risk factor for these events. If seizure did not stop or hx not compatible, consider EEG or sending to a tertiary centre.
33
Treatment for infantile colic
Lactobacillus reuteri may reduce symptoms (CPS, 2022)
34
Description of a 2 month old baby with colic. Tolerating breastfeeding well, normal exam. What is the best management? Encourage mom to continue breast feeding Add cows milk based formula in diet Add soy based formula in diet Simethicone
Encourage mom to continue breast feeding
35
For which medical conditions does CPS recommend the use of probiotics?
Conditions requiring antibiotics: - Preterm and Low Birth Weight infants with SEPSIS (multi-strain) - NEC in neonates >1000g - Antibiotics-associated diarrhea (Lactobacillus rhamnosus and Saccharomyces boulardii ) - Clostridium difficile-associated diarrhea (CDAD) for children on antibiotics (Use of probiotics to treat established CDAD is not recommended) - Helicobacter pylori in conjunction with standard therapy (assist with eradication and decrease side effects of treatment) Other Conditions: - IBS and other functional GI disorders (lactobacillus) -Infantile Colic (Lactobacillus reuteri) - Atopic dermatitis and eczema
36
15 yo M mild tic disorder, recently dx w/ ADHD. Having difficulty with attention in school. How do you treat? A. methyphenidate B. clonidine C. risperidone D. CBT
Methylphenidate Can use stimulants in co-occuring tic disorders with ADHD but need to monitor closely
37
Infant born at 32 weeks, now 6m presents with a one day history of decreased feeding. She is intermittently fussy with NB NB emesis. What is the most likely risk factor for her condition? Prematurity Rotavirus vaccine Vitamin D
Rotavirus vaccine - presenting with intussussception
38
4mo breastfed baby, mom concerned because of arching, fussiness, regurgitates 4x per day and some frank emesis. Has been growing well with weight at the 50th percentile. How do you manage? Start lansoprazole Stop BF and start hydrolyzed formula Provide education and reassurance Elevate head of the bed to 45 degrees
Education and reassurance (physiological GER)
39
5 Steps to Engaging with Vaccine-Resistant Parents (2019 CPS) with 3 new recommendations from 2024 - Great option for OSCE station
1. Understand the key role that sound vaccine advice from a health care provider can play in parental decision-making, and do not dismiss vaccine refusers from your practice 2. Use presumptive and motivational interviewing techniques to understand a parent’s specific vaccine concerns 3. Use simple, clear language to present evidence of disease risks and vaccine benefits, fairly and accurately 4. Reduce barriers to vaccine administration 5. Community protection (herd immunity) does not guarantee personal protection Three new recommendations follow: - Be sensitive to the lived realities of racialized and Indigenous parents, and their resultant distrust of the health care system. Whenever possible, engage an Indigenous or racialized health care team to help with vaccine counselling. -Directly address issues of pain and anxiety when parents raise them on behalf of children. -Whenever possible, facilitate or refer parents to special or after-hours vaccine clinics.
40
Which of the following statements regarding oral health are true? a) The first teeth to erupt are usually the lower central incisors at 5-8 months b) The last primary teeth to erupt are the upper canines at 16-20 months c) Dental extraction of caries is a rare procedure in children d) 20 % of Canadian kids 6-11 years have had a cavity e) The most common causative organisms for dental caries is Streptococcus viridans
a) The first teeth to erupt are usually the lower central incisors at 5-8 months ** 57 % (!) of Canadian children 6-11 years have had a cavity with an average of 2.5 teeth affected by decay
41
18 month old baby has no teeth yet. What is your next step? TSH Reassure Ferritin Karyotype
TSH
42
what are an Early Childhood Caries (ECC)?
the presence of one or more decayed, missing (due to caries) or filled tooth in any primary tooth in a preschool aged child 6-8 % have ECC but >90% in some Indigenous communities **Children with ECC have a higher risk of tooth decay in permanent teeth**
43
Differential for delayed eruption of teeth
Delayed eruption hypopituitarism hypothyroidism osteoporosis Gaucher disease Down Syndrome cleidocranial dysplasia Rickets
44
What is the most common chronic disease of childhood?
Dental Caries
45
Risk factors for Early childhood caries (ECC)?
Early childhood caries (ECC): Defined as tooth decay in any primary tooth in a child <6yo - Transmission of Streptococcus mutans from caregiver to child - Prolonged bottle feeding - Consumption Sugar sweetened beverages and sugary snacks - Exposure to tobacco smoke - Obesity is also a RF (unclear if separate from dietary factors) - Oral hygiene Causative triad: cariogenic bacteria, fermentable carbohydrates, host susceptibility (integrity of tooth enamel)
46
Prevention of early childhood caries?
- prenatal care for Moms (to prevent transmission of strep mutans) - Fluoride (in toothpaste, in water) - oral health education (esp at time of first tooth eruption) - community based promotion of less sugary drinks and encourage breastfeeding
47
You are a paediatrician working in a rural Indigenous community with high rates of early childhood dental caries. You want to create a community based health promotion initiative to combat this problem. What would be the highest likelihood of success? Discuss early childhood oral hygiene at each well-child visit Promote supervised use of twice daily fluoridated toothpaste Advocate for alternatives to sweetened beverages School based oral hygiene screening
Advocate for alternatives to sweetened beverages
48
early childhood caries in indigenous children are more likely to...?
- occur at an earlier age - higher prevalence (eg 90% in some indigenous communities vs 6% in urban centers) - be more severe Earlier acquisition of Strep mutans in this population likely due to increased rates of poverty (household crowding, family size, nutrition and other behavioural factors)
49
Assessment and treatment of early childhood caries per CPS (6 steps)?
1. Caries risk assessment Anticipatory guidance, fluoride varnish, referral to dentist 2. Sealants On primary molars after eruption, fluoride varnish every 3-6 months in high risk populations 3. Interim Therapeutic Restorations Minimally invasive dental restorative techniques to prevent dental caries in young and uncooperative children 4. Silver Diamine Fluoride Caries arrest (side effect of turning lesion hard and black) Goal to prevent operative repair of severe ECC 5. Repair under GA Expensive, failure of prevention 6. Access to Early Oral Health care "dental home" established within 6 mo of first tooth eruption Comprehensive dental health care by 12mo of age Shortage in indigenous communities
50
what is Amblyopia?
reduced vision in the absence of ocular disease as a result of the brain not recognizing input from the eye. Often due to strabismus or a refractive error
51
application of fluoride toothpaste?
<3y brushed by adult w/ grain of rice sized portion of fluoridated toothpaste 3-6yo assist brushing w/ green pea sized portion of fluoridated toothpaste BID
52
what does fluoride do?
* Inhibits plaque by killing/inhibiting bacteria * Inhibits demineralization by making teeth more resistant to acid * Enhances remineralization * Reduces dental caries (strong evidence) * Risk is fluorosis (dental discolouration) if more than 0.7 * Regular use of fluoride mouth rinses have been shown to reduce tooth decay in older children * The Canadian Dental Association endorses water fluoridation and topical fluoride use
53
what is Strabismus ?
misalignment of the eye in any direction which may be constant or intermittent
54
what is Refractive error?
inability of the eye to focus the image. Usually correctable with a lens
55
what are cataracts?
opacification of the lens
56
what visual abilities does a <1 month old have?
Fix on face (0-1mo)
57
At what age does visual acuity develop?
around 3 years old (42 months)
58
what visual screening assessment is required for 0-3 month olds?
examine external eye structures red reflex
59
what visual screening assessment is required for 6-12 month olds?
ocular alignment for strabismus - have them fix and follow a target (plus same screening as 0-3 mo of red reflex and examining external eye structures)
60
what visual screening assessment is required for 3-5 year olds?
Visual Acuity Testing Plus all previous testing: strabismus, red reflex, external eye structures
61
why is early screening for hearing impairments important?
-Without early diagnosis, diagnosis is usually at 2 years old and associated with poor communication and social skills -Language impairment (directly proportional to degree of hearing impairment) -- *Permanent hearing loss is one of the most common congenital disorders*
62
Definition of hearing loss
Hearing loss is defined based on the degree of loss measured in decibels Profound hearing loss is > 80 dB (Normal 0-20 dB)
63
what are the 3 types of hearing loss?
sensorineural, conductive and mixed
64
what is sensorineural hearing loss?
damage to the cochlea (inner ear) or auditory nerve Most common form of neonatal hearing loss
65
what is conductive hearing loss?
mechanical problems of the outer ear, tympanic membrane, or ossicles that interfere with conduction of sound to the inner ear eg. middle ear fluid
66
what are the causes of sensorineural hearing loss?
Genetics, infection (meningitis, CMV, etc), gentamicin, cisplatin, hyperbili and blasting music through headphones -- 50% genetic (1/3 syndromic: Alport's, Jervell-Lange-Nielsen, Neurofibromatosis, CHARGE) Congenital Infections: CMV, toxoplasmosis, rubella, syphilis, zika Infection: Meningitis (most common cause of postnatally acquired ԁеаfոеss in ϲhilԁhοoԁ) Severe hyperbilirubinemia (bilirubin is toxic to auditory nerve) Ototoxic Medications: - Aminoglycoside antibiotics (Gentamicin, Tobramycin) - Chemo (Cisplatin) Trauma: kids blasting music through headphones
67
Which of the following is true of Universal Newborn Hearing Screen recommended for all Canadians a) AABRs are the primary, initial screen that makes up universal screening b) Mild congenital hearing loss can be missed in most programs c) In unscreened children, hearing loss is identified as a speech delay at an average of 36 months of age d) Admission to the NICU for 24 hours is a risk factor for neonatal sensorineural hearing loss
Mild congenital hearing loss can be missed in most programs
68
What are the two techniques for hearing screening of newborns?
Otoacoustic Emission (OAE) or Automated Auditory Brainstem Response (AABR) Both meet WHO guidelines -- Otoacoustic Emission (OAE) * OAE is a form of energy measured as sound which is generated by the outer hair cells of the human cochlea in response to auditory input * Probes in the baby’s ear canal sends a sound stimulus and then simultaneously records emissions returning from the outer hair cells of the cochlea via the middle ear * OAEs can be recorded in 99% of normally hearing ears * If there is a loss of 30 dB or greater the response is absent Automated Auditory Brainstem Response (AABR) * Records brainstem electrical activity in response to sounds presented via earphones * Evaluates the auditory pathway from the external ear to the level of the brainstem
69
Intervention strategies for hearing loss in children
- multidisciplinary team (GP, pediatrician, ENT, SLP, audiologists) - speech therapy - sound amplification devices - hearing aids - cochlear implants (surgically placed in the cochlea to stimulate auditory nerve)
70
At what age do the grand majority of children reach daytime continence (ability to control when they pee)?
1.5 years old: 98% of 36-month-olds can control when they pee
71
when to begin toilet training and when to expect full control?
Begin at 2-3 years old (slightly younger in girls) Can take up to 6 months to achieve full control -- Fun Fact: kids are physiologically ready by 18 mo (control of sphincter etc.) but not psychologically ready (need language skills, desire for independence, respond to positive reinforcement)
72
what is the definition of enuresis?
Bedwetting in 5+ year olds "urinary incontinence during sleep in children >5 yrs old"
73
Classification of Enuresis
Primary = never attained night-time bladder control Secondary = achieved night-time bladder control for >6 months before enuresis. Usually psychological or physical comorbidity Monosymptomatic Enuresis (MSE) = just bedwetting Non-Monosymptomatic Enuresis (NMSE) = enuresis plus one of: - Excessive (≥8 times/day) or minimal (≤3 times/day) voiding frequency - Voiding postponement, holding maneuvers - Daytime incontinence - Urgency or dysuria (without urinary tract infection) - Interrupted flow - Sensation of incomplete emptying
74
what are common comorbidities associated with enuresis?
Constipation (82%) Developmental Delay OSA Mental Health Issues
75
11 year old boy who has never been dry at night. Father had nocturnal enuresis until age 10. Having difficulty and not able to spend time at his friends’ houses for sleepovers. What is the best advice regarding management? a. Alarm b. Imipramine c. DDAVP d. Oxybutynin
DDAVP for sleepover
76
What are less common but more serious causes of enuresis? (10)
diabetes mellitus or diabetes insipidus, renal disease, hyperthyroidism, spinal dysraphism (=spina bifida occulta), infections, seizure disorders, cardiac arrhythmias, child maltreatment, trauma, and psychosocial stressors, including bullying
77
Is there any genetic link with enuresis?
Yes, strong genetic link (gene on Chromosome 13q)
78
what percentage of 7 year olds have enuresis?
10% -- Enuresis Incidence: * 15% of 5 year olds * 10 % of 7 year olds * 5 % by 10 years * 2 % of adults
79
A 5 year old boy has new onset enuresis. The best initial intervention for this child is to: a) Wake him and take him to the bathroom before the parents go to bed b) Punish him in the morning c) Obtain a urinalysis d) Use an alarm e) Write a prescription for DDAVP
Obtain a urinalysis urinalysis and voiding diary are the mainstay of investigations for Secondary and Non-Monosymptomatic Enuresis (NMDE) No investigations are required for Primary Monosymptomatic Enuresis
80
First and Second Line Treatment for Enuresis
In primary monosymptomatic enuresis, the mainstay of management is education and reassurance that no treatment is necessary. Virtually all children and adolescents will outgrow their bedwetting with time. First Line Tx: Education and Reassurance Second Line Tx (for ongoing distress despite education and reassurance): - void when they wake up and before bed, and every 2-3 hrs - drink less water after dinner - avoid constipation ^^reward kids who do this^^ Do not incentivize “dry nights” which are not in their control
81
Third Line treatment for Enuresis
Alarm x 4 months + Desmopressin PRN (for sleepovers) Alarm devices * Aims to teach child to respond to full bladder while asleep by alarming when voiding begins * Parent and child need to be motivated * Can take months to see improvement (12-16 weeks) * Costs about $80 * Permanent cure rate of up to 50 % (initial response of 60-80 % with relapse rate of up to 50% when alarm is stopped) vs 15 % spontaneous remission per year * Discontinue when dry x 14 consecutive nights Desmopressin acetate (DDAVP) 0.2mg – synthetic analogue of ADH * Recommended for short term use (sleepover camps, sleepover parties etc.) OR continuous use for 3 months then 2 weeks break to see if they are cured, if not then continue for another 3 months (hugely positive psychological benefit of being dry for 3 months) *alarms have higher success rate so still preferable over continuous DDAVP *you MUST counsel to drink less water after dinner (80% of water before 4pm) * Half the dose for the last two weeks * Monitor ‘lytes q 3months
82
What is the definition of Functional Constipation?
Must have 2 or more of the following and have a developmental age of at least 4 years old: * Two or fewer defecations in the toilet per week. * At least one episode of fecal incontinence per week. * History of retentive posturing or excessive volitional stool retention. * History of painful or hard bowel movements. * Presence of a large fecal mass in the rectum. * History of large diameter stools that may obstruct the toilet * Must fulfil criteria once per week, for at least 2 months and not meet criteria for Irritable Bowel Syndrome (IBS)
83
An infant has a sacral dimple. What would make you more concerned about spinal dysraphism? A. slate-gray nevus over dimple B. Located 2 cm from anal verge C. 3 mm in diameter D. Located above the gluteal cleft
Above the gluteal fold Red flags > 2.5cm from the anal verge, > 0.5cm width across the base deep, unable to visualize base associated cutaneous findings eg hemangioma, tufts of hair)
84
what is an new treatment option to treat enuresis if significant psychological distress? (early evidence)
TENS Transcutaneous electrical neurostimulation (TENS) provides electrical stimulation to the sacral nerves responsible for bladder control
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Examining an 18 month old child and noticed this condition of the teeth. (Photo of white spots on teeth) What is the likely diagnosis? Dental caries Dental fluorosis Vitamin D dependent rickets Dentinogenesis imperfecta
Dental Fluorosis Too much fluoride can cause dental fluorosis - at around 0.7ppm of fluoride.
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4y boy with a bone age of 3 years. You are given 2 growth charts. The first chart shows growth from 0 to 2 yo going from 15th to 3rd %tile for both height and weight. The second chart shows height and weight tracking at 3rd %tile from 2 to 4 yo. What is the most likely cause? Familial short stature Constitutional delay in growth Malnutrition Growth hormone deficiency
?Constitutional delay in growth --- Approach to Short Stature (Height <3rd percentile) Otherwise well or associated low weight, dysmorphic or delayed puberty (red flags)? If well, assess bone age. If Bone Age = Chrono Age, it is Familial short stature. If Bone age < Chronological age, it is Constitutional Delay If red flags, are height and weight proportionate or disproportionate? If disproportionate, Rickets or Achondroplasia If proportionate and dysmorphisms = Tris 21 or Turner (or Prader-Willi or Russel-Silver) if proportionate and non-dysmorphic, child not getting enough nutrients (intake, neglect, disordered eating, celiac, IBD, chronic disease like renal failure, CF or congestive heart failure), endocrinopathy (hypothyroid, GH deficiency etc) or intrauterine insult (IUGR, SGA or fetal alcohol syndrome)
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15yo male with blood pressure of 128/78 (avg of 3) during visit. What do you do next? Ambulatory monitoring Electrolytes, Creatinine Repeat in 6 months Repeat in 1-2 week
Repeat in 6 months This patient has "elevated BP" Definition of HTN : = BP elevated BP at 3 separate visits Elevated BP > 120/80 Stage 1 BP >130/80 Stage 2 BP >140/90 Hypertensive Crisis: Elevated BP with end organ effects Recall: If cuff too small, can falsely elevate BP Cuff on lower limbs, can false elevate BP
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where is the best location for a blood pressure cuff?
Best cuff location is Right (Pre-Ductal) Arm - just in case they have aortic coarctation
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Hypertension has been confirmed in an obese 6 year old. They have a father with a history of hypertension. What investigations are required?
This is primary HTN Children ≥6 yrs do not require an extensive evaluation for secondary causes of HTN IF they have a positive family history of HTN, are overweight/obese, or do not have findings suggestive of secondary hypertension
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What are red flags for secondary hypertension?
<6 years old Teenagers with low BMI and no other RFs for hypertension (obesity, family history of HTN)
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What are causes of secondary hypertension?
Renal (MOST COMMON): GN, interstitial nephritis, renal scarring, obstructive nephropathy, polycystic kidney disease Endocrine: hyperthyroidism, Cushing syndrome, neuroendocrine tumours Coarctation of the Aorta Iatrogenic: Medications, Fluid Overoad Prematurity; Bronchopulmonary Dysplasia
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what are red flags for renovacular HTN?
BP >150/100 HYPOkalemia Diastolic HTN Needing ≥ 2 antihypertensive drugs Creatinine goes up with ACEi use Genetic syndrome associated with HTN Vasculitis Trauma to kidneys (or vascular insult) Mid-abdominal bruit
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Recommendations for screening for hypertension?
Begin annual screening at 3 years old for everyone If obese, diabetes, kidney disease, CoA or drugs that raise BP, screen more often than once per year Begin screening younger than 3 yrs old if: - Baby things: premature <32 wks, SGA, VLBW, umbilical arterial catheter (UAC), congenital heart disease - Sick Kids: cancer, raised ICP, renal disease (includes UTIs, proteinuria, hematuria)
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Kid with BP 125/85, next step?
This is "Elevated" BP as >120/80 Recommend: DASH diet Normal BMI Exercise then rpt BP in 6 months if still high, check again in 6 months if still high, ambulatory BP monitor and do HTN work up +/- refer to nephro
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Kid with BP 135/85, next steps?
This is stage 1 HTN as >130/80 Recommend: DASH diet Normal BMI Exercise then rpt BP in 2 weeks if still high, repeat in 3 months if still high, ambulatory BP monitor and do HTN work up +/- refer to nephro
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kid with BP 145/95, next steps?
This is stage 2 HTN as >140/90 Recommend: DASH diet Normal BMI Exercise then rpt BP in 1 week if still high, do HTN work up AND refer to nephro within 1 week
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What is the work up for a child with hypertension?
Need to do 3 measures to confirm hypertension Creatinine, BUN, lytes, UA, renal US with doppler to r/o RAS for <6 or >8 if normal wt, suspected renovascular complications of HTN Lipid profile, fasting glucose if obese, add A1c, AST/ALT and fasting lipids
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Indications for medications in hypertension?
Despite DASH diet and exercise, elevated or stage 1 HTN persists for 6 months Stage 2 HTN Co-Morbid diabetes Chronic Kidney Disease
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Pharmacological management of hypertension?
Prior to starting pharmacotherapy for HTN, all children must receive an ECHO to assess for target end organ damage (Ex: LVH) 1st Line: ACEi (Perindopril, etc.) ARB (Candesartan, Losartan) Calcium channel blocker (Amlodipine, Nifedipine) thiazide diuretic (Hydrochlorothiazide) Increase dose q2-4 wks until BP <90th percentile
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5 yo boy in your offices screened for blood pressure, found to be between 90-95%île for height and weight. What is most appropriate next step? Renal ultrasound with Doppler Lifestyle modifications - DASH diet and exercise Repeat BP in 1-2 weeks Serum lytes, creatinine, and urinalysis
Lifestyle modification Repeat BP in 6 month - three separate measures of hypertension to make a diagnosis
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Parents would like to switch their preterm baby's cow milk formula to soy formula. What do you counsel them about? A) osteopenia b) macrocytic anemia C) acrodermatitis enteropathica D) Scurvy E) Rickets
Osteopenia Soy formula use in preterm infants with BW <1800g results in low phos, high ALP and osteopenia
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2 year old previously healthy boy, developmentally normal, has a 6 month history of not eating well. At home, his parents offer him a varied diet at regular meal times however he only eats very small amounts even with parental coaxing. In daycare, he is eating well. His height and weight are tracking along his curve on the 25th (height) and 3rd (weight) centiles. What is the next step in management? A- Start Iron supplementation B- Cyproheptadine C- Start a new formula (toddler’s formula) D- Behavioural modification at home (for parents)
Behavioural modification at home (for parents) -- Redacted CPS statement Eating should be enjoyable - no coercion, coaxing, bribing, threatening or punishing Forcing leads to resistance
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18mo referred for Autism assessment. What tool do you screen / assess with? A- Childhood Autism Rating Scale (CARS) R- Autism Diagnostic Observation Schedule (ADOS) C- Social Reciprocity Scale D- Weiss Scale
Autism Diagnostic Observation Schedule (ADOS): diagnostic tool for > 12 months We are tryring to diagnose ASD and this is the correct tool for this age -- Note what is DIAGNOSTIC vs SCREENING Childhood Autism Rating Scale (CARS): diagnostic tool for 2+ years old Autism Diagnostic Observation Schedule (ADOS): diagnostic tool for > 12 months Social “Responsiveness” Scale: for 2.5-4.5 year olds (preschool age for screening for early ASD sx) Weiss Scale: functional impairment scale for ADHD
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9) Most common cause of sacral agenesis and can even cause lumbar or thoracic a. IDM b. Trisomy 13 c. FAS
a. IDM Sacral genesis is defined as the absence of part or all of >/2 lower vertebral bodies. They have a flattened buttock, and a low, short gluteal cleft, but usually have no orthopaedic deformity. Some have high-arch feet. Palpation of the coccygeal area detects the absent vertebrae. This condition is more common in infants of Diabetic mothers.
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5yo girl with cerebral palsy who is non-verbal and wheelchair bound. She feeds orally and is very eager. Her parents take 90-120 minutes to feed her purees three times a day. She is on PPI for a GERD with minimal vomiting. Her weight dropped from 50th to 40th percentile over the past 2 years. She had one aspiration pneumonia at age 2. What is the most significant indication for G tube insertion? GERD Failure to thrive Aspiration pneumonia Duration of feeds
Duration of Feeds Her feed time would add up to 6 hours a day, likely tiring out and potentially increasing metabolic demand which can lead to losing weight Not FTT, 50 to 40%ile is not passing growth curves GERD well managed Only had 1 aspiration PNA so not "recurrent"
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When should we initiate conversation with parents for a G tube in their child?
- neurological impairment (mention early) - poor oral intake and wt loss despite calorie supplementation - recurrent aspiration pneumonia - refractory GERD - refractory dysmotility *consider GJ if severe GERD or recurrent aspirations
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benefits of G tubes (in the correct patients)?
- improved nutritional status (weight) - reduced need for hospitalization - antibiotics for chest infections - decreased feeding times - decreased caregiver worry about nutrition - ease of medication administration and - improvement of quality of life
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Risks of G-tube feeding, both short and longterm?
Short term (complications from insertion): - peritonitis (2%) - bleeding - infection - anaesthesia related - organ puncture - perioperative death (rare) Long term: - tube blockage, dislodgement, breakage - stoma infection, bleeding, hypergranulation - granuloma - consider silver nitrate - Worsening GERD
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16 year old comes to your office. She is sexually active but has not received HPV vaccine. What is the most appropriate step in her management? Pap smear HPV vaccination Pap smear at 21 and vaccination Nothing
HPV vaccination Pap smear is not indicated until 21 yrs Recommended catch up given sexually active and vaccine recommended >9yo
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When do we do PAP testing?
21 years old
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Transmission of HPV?
Direct Transmission: through mucous membrane contact (usually sexually) Vertical Transmission: Juvenile-onset Recurrent Respiratory Papillomatosis (JoRRP) = recurrent papillomas of the respiratory tract, mainly the larynx. - presents 2-6 yrs old - progressive dysphonia (hoarseness), followed by stridor and respiratory distress - from HPV 6 and 11 - no cure, just remove the papillomas, often need a tracheostomy HPV incidence lifetime 70%
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Presentation of HPV
Human Papillomavirus (HPV) Clinical Manifestations: - Asymptomatic (most common) - Warts (HPV 6, 11 cause 90%) - Malignancies (cervical, anal, penile, oropharyngeal) - 80% from HPV 16 or 18; needs to persist for 1 year in cervix before it comes malignant
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Risk factors for HPV?
- many sexual partners, early age of sexual intercourse, sexual abuse, STIs - tobacco/marijuana use - immunosuppressed - HIV infection - MSM MSM, HIV, immunosuppressed are higher risk for adverse outcomes from HPV
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When do we administer the HPV Vaccine? What about those who did not get the HPV vaccine at the recommended age?
9-13 years old 2 doses, 6 months apart Catch up for 15-26 year olds: 3 doses If immunocompromised, also 3 doses (HPV is not a live vaccine) GOAL is to administer vaccine BEFORE exposure to HPV (ie pre-sexual contact)
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Child with Autism has a very restrictive diet. She has iron supplementation but her anemia is not responsive. What is the most likely associated deficiency? Vitamin B12 Vitamin C Vitamin A Vitamin D
Vit C - which is important for absorbing iron -- All of these vitamins would most likely be low in ASD pts with restrictive diets: - Vit A deficiency => Xerophthalmia - Vit C deficiency => Scurvy - Vit D deficiency => Rickets - Vit B12 - often ASD kids eat lots of milk and cheese, which have vit B12 - Iron Deficiency
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3. 4 yo F, brought in by CAS worker due to concerns about sexual abuse. Exam shows vulvar irritation and discharge. What to do? a. STI swabs and culture b. Avoid bubble baths c. Reassure d. Something else
Something else - AKA thorough history and physical exam based on index of suspicion. Per CPS “An STI from sexual abuse is rare in prepubescent children in Canada… testing for STIs should be considered on a case-by-case basis
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50. What is the recommended vitamin D supplementation for a 6 month old baby living above the 55th latitude during winter months? a. 200 international units b. 400 international units c. 600 international units d. 800 international units
800 IU daily
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Young female medically complex with GDD, cortical blindness, deafness, seizures which are well controlled. GT fed and growing well. Parents are concerned about her sleep. She has no problem falling asleep but wakes up multiple times throughout the night. What is the most appropriate next step in management? Clonidine Melatonin Acetaminophen Lorazepam
Clonidine
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A 15 year old otherwise healthy female is sexually active and comes in for a annual health check. According to the Greig health record, which of the following should she get: Chlamydia, gonorrhea testing Chlamydia, gonorrhea and HIV testing Chlamydia, gonorrhea, HIV testing and Pap smear
Chlamydia, gonorrhea and HIV testing No PAP before 21
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15 yr M with 5h per day of screen time. Performing well academically. No mood concerns. A. This is a normal amount screen time for this age B. Recommend <2h per day. C. Make sure it is not affecting sleep or face to face time D. Can continue as much screen time as desired as long as grades aren’t affected
Recommend <2h per day
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46. A 10 month old baby wakes up every 2 hours and needs to be rocked back to sleep by his mom. What is the most likely cause? Benign rolandic epilepsy Sleep onset association disorder Night terrors
Sleep onset association disorder
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4 mo ex 30 weeker with bullous lesions in the diaper areas and a red scaly patch on his chin in the context of diarrhea. Exclusively breastfed. Has trialled steroids, fungal creams already. What to do? A. Zinc supplement B. Hydrolyzed formula C. Mom alter diet D. Antibiotics
Zinc supplement Zinc deficiency causes vesiculobullous, eczematous, dry, scaly skin lesions in diaper and perioral area Zinc deficiency may be due to: * breastmilk being low in zinc or, *congenital zinc deficiency (autosomal recessive disorder with inability to absorb zinc, classically presents with rash and diarrhea when weaning off of breastmilk to cow's milk) *causes growth delays *requires zinc supplementation for life
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2 month old term baby has a formula feed and then stops breathing, has decreased respiratory effort, eyes look panicky, the baby turns red and then blue. Mom gives him a few back pats and he coughs and milk sprays out of his nose and mouth. He is sleepy after the event. What's the best next step? CXR Upper GI series Start lansoprazole Observe and reassure
Observe and Reassure This is GERD, not a BRUE (since we have an explanation) -- recall low risk BRUE: >60d, >32wk, only 1 BRUE, duration <1min, no CPR from healthcare provider (not parent), no concerning features like dysmorphism/seizures tx: hx and exam, observe, no overnight monitoring (4 hr enough), no investigations (could consider ECG and pertussis swab) 2019 AAP: what to do with high risk BRUE pts? - CRM monitor for 4 hrs in emergency department - screen for NAS - observe feed - all high risk: do ECG, RPP, pertussis swab, CBC (look for anemia or polycythemia), blood sugar, gas with lactate. Do more ix if concerns on history or exam. RECALL that if there is any diagnosis then it is not BRUE
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Which ADHD medication is most likely to cause hypertension if abruptly stopped? Methylphenidate Atomoxetine Dextroamphetamine Guanfacine
Guanfacine --- Guanfacine (Intuniv) is a selective alpha 2a-adrenergic receptor agonist which means it blocks norepinephrine and epinephrine from being released from the sympathetic nervous system (ie blocks the fight or flight response) alpha 2 adrenergic blockers like guanfacine (intuniv) and clonidine decrease HR and BP, increases blood flow to muscles/brain and slows digestion THUS there is a danger of REBOUND HYPERTENSION when guanfacine is abruptly stopped CPS statement describes how to titrate down when stopping it
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A 10 year old with ADHD complains of sleep problems; his legs don’t stop moving during the night. What investigations? TSH and T4 CBC and ferritin Calcium and magnesium
CBC and ferritin -- Restless Leg Syndrome is associated with iron deficiency and low ferritin, and frequently comorbid with ADHD patients The five diagnostic criteria for RԼЅ are: An urge to move the legs, usually accompanied by uncomfortable or unpleasant sensations in the legs The symptoms begin or worsen during rest or inactivity (eg, lying down or sitting) The symptoms are relieved by movement The symptoms occur exclusively or predominantly in the evening or night These symptoms are not solely accounted for by another medical or behavioral condition if ferritin <50, treat with iron supplement 3mg/kg (up to 130mg) if normal ferritin, consider gabapentin
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What is the best treatment for ADHD in a five-year-old? Parent behavioural training Methylphenidate Amphetamine Non-stimulant
Parent behavioural training (2024 consensus)
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which risk factors predispose to ADHD?
in-utero alcohol/tobacco exposure, low BW, hypoxic-anoxic brain injury, epilepsy, TBI
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Which genetic syndromes have a higher prevalence of ADHD?
Fragile X Turner Syndrome Tuberous sclerosis Neurofibromatosis 22q11 deletion syndrome
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Before making ADHD diagnosis in preschoolers, AAP recommends that parents of young children referred for ADHD assessment do what?
enroll in a parent training program
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DSM 5 Criteria for ADHD
DSM-5: Symptoms are severe, persistent (present before age 12, continuing longer than 6mo) and inappropriate for age/developmental level > 6 symptoms up to 16yo (adult > 5) either inattention or hyperactivity or both Symptoms associated with impairment in academic achievement, peer and family relations and adaptive skills Several symptoms in > 2 settings. Discrepancy of symptoms across setting, important to identify why Specify type (combined, inattentive, hyperactive/impulsive) and severity (mild/moderate/severe based on sx and functional impairment) *not better explained by another disorder
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What are common mimics/comorbidities with ADHD?
- Learning Disorder, intellectual disability, language disorder - Sleep Disorder - Conduct disorder, ODD, anxiety, substance use, depression - Eating Disorder - Tic disorder - Autism spectrum disorder - Developmental Coordination Disorder (DCD)
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Non-Pharmacological Treatment of ADHD
- psychoeducation (helps parents understand ADHD better, reduces misperceptions, results in fewer parent-reported symptoms and increased pro-social behaviour) - shared decision making (review goals for improvement of academics, behaviour and interpersonal relationships; review all tx options) - parent behavioural therapy (teaches parental skills for behaviour problems; FIRST LINE FOR PRESCHOOLERS) -classroom management - daily report cards (improves adherence to classroom rules and academic productivity) - cognitive training (when older; working memory training) -organizational skills training - diet if dietary deficiency - Exercise (improves core ADHD sx and related anxiety/cognitive functions)
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Pharmacological treatment of ADHD
Review Caddra; know stimulant and non-stimulant options
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14y old boy with 4 weeks of chronic cough, fever. CXR showed left lower consolidation . Treated with amoxicillin and two weeks later has improvement of symptoms. Repeat CXR still shows small.Lt lower lobe consolidation. What is your next step? Rpt CXR in 4wks Repeat treatment with cefuroxime and azithro Consult respiratory CT chest
Rpt CXR in 4wks we do NOT recommend follow up CXRs if symptoms resolve. the persistant consolidation is likely radiographic delay. can rpt in 4 wks to prove it is gone. No more abx, CT or resp consult required if symptoms are resolved
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A 2 day-old months female failed twice the hearing screen. What to do? CMV IgM and serology Referral to ENT Eye exam CMV PCR on urine
CMV PCR Urine this infant has failed the screening test. They need to be referred to Audiology. CMV is a cause of congenital hearing loss - it must be tested within the first 21 days of life so do not delay in ordering it. the next best step is to order the CMV and refer to audiology so they have the result at assessment
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20. Child with acute otitis media is taking amoxicillin and has two episodes of bloody diarrhea, Is otherwise afebrile and well. Besides discontinuing the current antibiotic, what else would you do to manage this child? Close follow up PO metronidazole PO vancomycin PO clindamycin
Close follow up - likely antibiotic associated collitis, but well appearing.
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what is deficient in goat's milk formula?
folate
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You are seeing a 2-month-old for a routine check up. You notice flattening of the right posterior occiput, with the contralateral ear displaced anteriorly. What is the next step? Refer for helmet therapy Discuss positioning exercises Skull CT Skull X-ray
Skull CT
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Girl with itchy head. Upon closer inspection, you see live lice and eggs at the base of hairs. Mom asking when can she return to school? A) Does not need to be restricted from returning to school. B) Return when no more adult lice seen C) Return after one application if pediculocide D) Return when no more eggs/nits seen
Does not need to be restricted from returning to school
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treatment of lice?
Pyrethrins shampoo or permethrin 1% 2 treatments, 1 week apart must be >2 months old to use -- Apply to dry hair and leave on for 10 mins Create lather and then rinse Note: environmental decontamination not warranted (at most, can wash hats, pillowcases and combs)
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child with an itchy burning scalp rash, iafter treating lice with permethrin. next steps?
do not need second round of treatment, this is a common side effect
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Two siblings, 2 and 5 years old, of native descent present with 3-4 day history of erythematous and pruritic rash over flexor surfaces of wrists and elbows bilaterally. Symptoms are worst at night. There is no past or family history of atopy. What secondary conditions must you counsel for these children and other family members who may contract the same? Bacterial infection, anxiety Bacterial infection, depression, stigmatization, insomnia Bacterial infection, asthma, allergic rhinitis Bacterial infection, insomnia
Bacterial infection, depression, stigmatization, insomnia this is scabies
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first line tx for scabies?
5% Permethrin cream (leave on for 12hr) 2 doses, 7d apart must be >3mo stay home from school for initial treatment series wash ALL bedding and linen and clothes
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Patient still itchy 2 weeks after scabies treatment, do they need re-treatment?
hypersensitivity side effect of 5% Permethrin cream no indication for treating again
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when do we need to repeat treatment for scabies?
only with new lesions (burrows, papules) (persistent itchiness for a couple weeks is side effect of permethrin)
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risk factors for scabies?
poverty, overcrowding, bed-sharing, indigenous
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presentation of scabies?
burrows erythematous papules usually in fingers, wrist/elbow flexures, genitals, breasts generalized pruritis (worst at night)
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complication of scabies?
secondary bacterial infections stigma, depression, financial costs (Eg related to housing) insomnia (from pruritis)
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treatment for scabies if <3 mo old?
Sulphur (8-10%) in petroleum jelly daily for 3 consecutive days safe in infants (unlike first line tx of 5% permethrin cream)
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when can children with scabies go back to school?
for initial treatment series
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6 y.o. girl with a history of bilateral VUR and recurrent UTIs, including two febrile illnesses. Has been off antibiotics and infection-free for two years. Repeat U/S and VCUG show normal kidneys, but grade 1-2 reflux bilaterally. What do you recommend: consider operative repair repeat cystogram every 2 years restart prophylactic antibiotics continue non-interventional observation
continue non-interventional observation -- No evidence that prophylactic ABx prevent renal scaring or long term sequalae May still be considered in grade IV or V VUR or significant urologic anomaly NNT is large (9-42)! (less if higher grade reflux) and increases risk to abx resistance Not indicated for any grade of VUR Managing constipation is helpful – will reduce risk for UTI If using prophylaxis, use only for 3-6 months Septra or nitrofurantoin should be used unless hx of resistance DON’T use cipro or cefixime, just increases the risk of resistance
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OSCE: 11 mo old girl with 2/7 history of fever. No URTI symptoms, no sick contacts, euvolemic with good slightly decreased PO but normal number wet diapers. No red flag features for bacteremia PSWU complete in ED U/A comes back + for 10-15 WBC, 3-5 RBC, + leuks, +nitrites What is your diagnosis? What are your first steps in management?
assess she is stable confirm uncomplicated UTI do renal US then outpt abbx they return after this: failure of tx, unstable give bolus, broad spectrum abx and admit
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what patient population is most likely to get UTI?
Consider UTI in: > 2mo kids (<2mo approach like sepsis) Uncircumcised boys (overestimates due to contamination (up to 20%)) <3y + fever and no source up to 8% likely: urinalysis + culture (particularly>390 and>48h) Boys >3y: unusual to have first UTI w/o instrumentation - is there abN anatomy? this is a red flag
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What is most predictive of UTI on dipstick and urinalysis?
Dipstick: Best predictor is combo of Nitrites (gram-), Leuks (pyuria), and positive microscopy(bacteria). Most specific: nitrites at 98% specificity Babies can be nitrate negative but are febrile and have leuks CFU/ml: midstream clean catch - 1 x 10^8 CFU/L, In/out cath- 5x10^7 CFU/L suprapubic aspiration - any growth
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When do you need to organize investigations for a child with a urinary tract infection?
Renal function tests if: Complicated UTI or aminoglycosides>48h (do levels also) If not improving after 24 hours Persistent fever past 48hrs Hemodynamically unstable Blood cultures only if hemodynamically unstable
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a child with a UTI is found to be bacteremic, what do you do with the antibiotics?
if > 2months old and well apart from fever, no change to antibiotics if <2mo, treat like sepsis
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postpuertal girl with UTI sx without fever, what is the diagnosis and treatment
this is probably cystitis, give 2-4d of cefexime
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first line tx for febrile UTI, non-toxic pt without structural abN
cefixime 8mg/kg/d PO for 7-10 days dosed once daily if >12yrs old, ciprofloxacin (or younger pts if hx of resistance) other options are amox, amoxclav or septra
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what investigations are required for a <2yr old with first UTI?
complete renal US either during treatment or within 14 days if hydronephrosis (suggestive of VUR), then also add VCUG
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>2yr old with second UTI, what investigations should we do?
VCUG if diagnoses VUR, and it is grade IV or V, refer to uro/nephro
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Common comorbidities of enuresis
constipation ADHD, developmental delay OSA
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An athletic kid. He might make the track team! What is your advice to him? Drink 150-300 cc fluid per hour activity Have a salt rich snack and fluids after exercising Have a protein and fat rich snack after exercise High fats pre-exercise
Have a salt rich snack and fluids after exercising
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A 4mo exclusively breastfed baby boy is referred to you for severe atopic dermatitis and failure to thrive. He has intermittent blood in his stool. You are concerned for cow's milk protein allergy. What is the best next step? Ask the mother to restrict soy and dairy from her diet Switch to lactose free formula Switch to extensively hydrolyzed formula Recommend starting solids early and avoiding milk protein
Ask the mother to restrict soy and dairy from her diet (then if that fails then switch to extensively hydrolyzed formula)
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indications for PPI in GERD
erosive esophagitis including hematemesis, failure to thrive or feed PPIs (eg. lansoprazole): increases risk for infection (pneumonia) Increased risk for NEC and neonatal infections in VLBW infants Increased fracture risk
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how should parents introduce egg allergens to newborns?
Graduated: baked good, then ..., then eggs
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You receive a report of a positive CMV test on an infant who is now 2 months old but had thrombocytopenia at birth. His thrombocytopenia has resolved and he is asymptomatic. What is the most important thing to do now? a. Test mother and siblings for CMV b. MRI head c. Hearing screen d. Initiate treatment with gancyclovir for 6 weeks
hearing screen
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most common presentation of congenital CMV?
90% are asymptomatic
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what are the clinical features of congenital CMV?
SGA, microcephaly, jaundice, hydrops Petechiae Hepatosplenomegaly Seizures, poor suck, hypotonia, lethargy Hearing loss chorioretinitis, optic atrophy, microphthalmia, cortical visual impairement
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what are the lab findings in congenital CMV?
- low platelets - elevated ALT - elevated conjugated bilirubin - pleocytosis on CSF
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How can we reduce maternal risk of CMV?
Avoid contact with bodily fluids Avoid mucosal to mucosal contact with saliva (i.e. shared toothbrush) Avoid new sexual partners Hand hygiene (diaper changes, children’s toys, children’s laundry)
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When should we test infants for CMV?
**A failed newborn hearing screen or confirmed sensorineural hearing loss (SNHL)** - symptoms of CMV - maternal CMV infection - Fetal ultrasound with findings suggestive of cCMV - Placental pathology consistent with CMV infection potential risk: -HIV exposure -Primary immunodeficiency
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How do we diagnose congenital CMV?
Urine CMV PCR BEFORE 21 days of life (gold standard) -- can test saliva but must be confirmed with urine PCR
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What are the indications for treatment of congenital CMV?
CNS disease: seizures, poor suck, hypotonia, lethargy Chorioretinitis Severe single or multi-organ disease
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what is the treatment of congenital CMV?
6 MONTHS of valganciclovir (16mg/kg PO BID) treatment MUST commence within the first month of life
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An infant has been diagnosed with congenital CMV by urine PCR within 21 days of life (gold standard) - what are the next steps in evaluation?
CBC, bilirubin, ALT/AST Head US Hearing evaluation ophthalmological evaluation
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You are following a 6 year old boy in your clinic who takes a daily ICS for asthma. Parents report using 2 puffs BID of Flovent for the past 3 months for cough. Which of the following would be most suggestive of adrenal suppression? New onset polyuria Tanned colored skin BMI > 97%ile Poor vertical growth
Poor vertical growth
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True or False – a gradual taper of glucocorticoids can help reduce the risk for adrenal insufficiency
false
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S/sx of adrenal suppression?
- POOR LINEAR GROWTH (#1 symptom) - poor weight gain - anorexia - N/V - malaise - headache - abdominal pain - myalgia/arthralgia - psychiatric sx - CUSHINGOID features adrenal suppression is so vague and looks like a minor viral illness
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signs of adrenal crisis?
- hypotension - hypoglycemia - seizure or coma
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Risk for Adrenal Suppression?
>2 weeks of glucocorticoids Multiple short courses of GC Higher doses, longer courses, evening dosing ICS doses > 500mcg/day fluticasone Concomitant intranasal steroid use > 3 mo of use Swallowed oral budesonide for tx of EoE for > 1 mo NEED TO ORDER MORNING CORTISOL IN THESE CASES AS WE DONT WANT TO MISS ADRENAL SUPPRESSION Cortisol level less than 100 nmol/L is concerning!
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How to taper oral steroids?
NO TAPER < 1 month of use 1-2 week taper for 1-3 mo of exposure 3-4 week taper for > 6 mo of exposure Higher risk for AS when GC dose of 8 mg/m2/day hydrocortisone equivalent Consider testing morning cortisol level (concerning level <100nmol/L)
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A patient on inhaled corticosteroids needs to start clarithromycin antibiotics, what considerations do you need to make
both of those meds can cause adrenal suppression - pause the ICS Meds that increase risk for ICS: CYP3A4 inhibitors, including several antiretrovirals (e.g., ritonavir), antifungal agents (e.g., ketoconazole), and select antibiotics (e.g., clarithromycin), prolong the biologic half-life of GCs. These medications have been implicated in several cases of symptomatic AS associated with relatively low doses of ICS, and are reported to prolong duration of AS in systemic GC exposure 
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33. What is the most likely side effect of inhaled steroids? Decreased linear growth. Immunosuppression Moon facies Hypertension
Decreased linear growth - usually 0.5cm to 1cm decrease in final height.
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You decide to investigate for adrenal suppression in an asthmatic patient with IC levels >500mcg/day fluticasone - what do you order and what values are significant?
A first morning cortisol between 100-275nmol/L should be used as a threshold for risk for AS in asymptomatic patients ACTH stim test expect to see a rise in cortisol levels between 350-500nmol/L
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A two year old child is brought in by her parents for concerning behaviour. She cries and screams when she is not able to get what she wants and sometimes these episodes are associated with her turning blue and having jerking movements. Parents want to know what to do about these episodes? Ignore the behaviour, then put the child in a time out afterwards Interrupt the behaviour with a time out before it escalates Give the child whatever they want to avoid the behaviour
Interrupt the behaviour with a time out before it escalates
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A 12 year old boy is breaking things at home, not listening to instructions and skipping school. He seems angry. What is the next best step? Parenting courses Start and atypical anti-psychotic Start an SSRI Call local law enforcement
Parenting courses
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what age should temper tantrums be gone?
5 years old (unless in a dysfunctional home)
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how to treat disruptive behaviour
Parenting program
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Approach to behavioural concerns
Hearing and vision screen Diet/feeding irregularities Sleep problems Screen for ADHD Screen for ASD Screen for primary language delay/communication disorder Consider separation/anxiety disorders
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A child begins head banging at 5 years old
HUGE RED FLAG Consider w/u for abuse, GDD, LD, anxiety, etc Head banging only normal up to 4 years old, very weird for it to start for the first time 5+ yrs old
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9 year girl, parents divorced. How does she handle it? A) Blames herself B) ? C) ? D) Chooses one parent and takes their side Repeat question about a 9 year old whose parents are getting a divorce and they ask what type of behavior she will exhibit: Developmental regression Pick sides (mother vs. father) and blame the other parent Try to make everyone happy Blame herself for the divorce
a- choose one parent and picks sides. b - pick sides and blame the other parent Developmental considerations 7-9mo attachment to primary parent <5yo: developmental vulnerability and age of peak attachment formation -> need predictable and safe environment with consistent access to emotionally available caregivers who response to their needs in a consistent/sensitive way. 4-5 yo children often blame themselves and become increasingly clingy with separation anxiety, externalizing behaviors, excessive fears of abandonment School aged children: strong sense of rules and fairness – prone to loyalty conflict and may take sides Adolescent: personality and identity are consolidated, youth need access to both parents and may choose to move between homes
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A 4 day old baby is seen in your clinic for jaundice. The pregnancy was unremarkable, no ABO incompatibility. The baby is breastfeeding well, voiding and stooling. The unconjugated bilirubin is 200. What is the best course in management? (Note bili curve is NOT provided) Start Phototherapy Reassure Check for G6PD Re-check Bili in 24 hours
Reassure Easy ways to remember which bili level is concerning (low risk): 24 hours – Treat if > 200 48 hours – Treat if > 250 72 hours – Treat if > 300 96 hours or greater – treat if > 340
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what level of bilirubin is severe hyperbilirubinemia?
Severe hyperbili: > 340 any time in the first 28 days of life Critical hyperbili > 425 in the first 28 days of life Consider G6PD testing in ALL infants with severe hyperbili Either TSB or TcB concentration should be measured in all infants during the first 72 h of life. Conjugated bilirubin fraction should be measured if persistent jaundice ( > 2 weeks) and/or hepatosplenomegaly 
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what concentration of fluoride is optimal?
“ A suitable trade-off between caries and fluorosis occurred at around 0.7 ppm of fluoride ” need to balance reducing cavities and preventing side effect of fluoride which is fluorosis (Unsightly mottling and pitting of the teeth, enamel striations, and in severe cases, ‘snow-capped cusps’ )
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when to supplement with fluoride?
When concentration of fluoride in the water is <0.3 ppm, then fluoride supplementation for THEE" recall 3 and thee as memory aid
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Define Global Developmental Delay
Global Developmental Delay (GDD): applies to children < 5 years of age ONLY Significant delay (at least 2SD below mean) in at least 2 developmental domains
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define intellectual disability
Deficits in intellectual functioning Deficits in adaptive functioning Onset of intellectual and adaptive deficits during the developmental period
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Approach to Evaluation of Global Developmental Delay?
Step 1: history and physical **audiology** **optho/optometrist** EEG if suspect seizure Step 2: **chromosomal microarray** **fragile X ** brain MRI if abN neuro exam, seizures, micro/macrocephaly MECP2 in girls **Tier 1 TIDE Investigations:** - amino acids - acylcarnitine, carnitine - homocysteine - copper, ceruloplasmin - biotinidase - urine: organic acids - urine creatine metabolites - urine purines, pyrimidines - urine glycosaminoglycans Tier 2: Brain MRI if not done Genetics/Metabolics consult for Tier 2 of TIDE protocol and gene panels Additional Testing: Thyroid testing - although TSH is on newborn metabolic screen Iron, Vitamin B12 - consider if pica Lead TORCH infections
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what are the red flags for inborn errors of metabolism?
Consanguinity Recurrent episodes of vomiting, ataxia, seizures, lethargy, coma Unusual dietary preferences Psychosis at a young age Organomegaly Severe hypotonia Progressive sensory deficits (cataracts)
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what are risks for lead toxicity?
Buildings with chipped or peeling paint built before 1978 (US) Lead in water source (lead water pipes) MEXICAN CANDY with tamarind Herbal remedies (particularly from India and China) Soil can contain lead particles
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what percentage of patients with severe intellectual disability undergoing whole exome sequencing identifies a causal mutation?
40% can only be ordered by genetics for now
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4 year old boy with 1-2 episodes of watery diarrhea per day, some encopresis. No abdo pain or distention. Normal physical exam except hard palpable stool in rectum and stool around anus. What workup do you need to do? A) TSH B) AXR C) No investigations needed D) Barium enema
No investigations needed
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A 4mo exclusively breastfed baby boy is referred to you for severe atopic dermatitis and failure to thrive. He has intermittent blood in his stool. You are concerned for cow's milk protein allergy. What is the best next step? Ask the mother to restrict soy and dairy from her diet Switch to lactose free formula Switch to extensively hydrolyzed formula Recommend starting solids early and avoiding milk protein
Ask the mother to restrict soy and dairy from her diet -- - If we think it is FPIAP then would be elimination from mothers diet - If we think it is FPIES (because of FTT piece) then would be trial of extensively hydrolyzed formula Dr. Bouma said she would choose Ask the mother to restrict soy and dairy from her diet but that this kid is likely going to end up on a hydrolyzed formula
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A mother of a 4 month old term, healthy, exclusively breastfed infant is starting radiation therapy for thyroid cancer. Given that she can no longer breast feed, some of her friends have offered their breast milk. Which of the following is true? Informal milk sharing is not encouraged Flash heating does not alter the nutritional content Donors may take domperidone to increase milk supply Donor milk is safe if the mothers have screened negative for Hep B, C, HIV and syphilis during pregnancy
informal milk sharing is not encouraged
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A 13mo girl with cerebral palsy, epilepsy, and dysphagia is on a thickened fluid diet. She presents with her second episode of aspiration pneumonia. She has a lot of drooling. What is the best next step? Adjust feeding position & texture Stop oral feeds and start NG feeds Start a PPI Start an anticholinergic agent
stop oral feeds and start NG feeds
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Mother of a 7 week old breastfed infant eliminated soy and dairy 4 weeks ago for bloody stools. Still having ongoing bloody stools but the infant is otherwise growing well without any abdominal pain, vomiting or diarrhea. What should you advise? Hydrolyzed formula Amino Acid based formula Eliminate egg and corn from diet Reassess in 2 weeks
Hydrolyzed formula (although amino acid based formula could be considered, this answer based on CPS)
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You are seeing an infant. He has a strong family history of multiple food allergies. His mother wants to know what to do to reduce his risk of food allergy. What do you recommend? a) Tell mother to restrict allergenic foods b) delay introduction of allergenic foods until 12 months c) Introduce allergenic foods at 6 months
Introduce allergenic foods at 6 months
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Babe crying everytime she stools, mom has been to many doctors due to this. Thriving well a) Stop breastfeeding b) Reassure c) Hydrolzyed formula 3wk old, has straining and is fussy 15 minutes before passing stools, stools are non bloody and soft. After passing stools is well and not fussy. Gaining weight well, is breast fed and is otherwise healthy. Mom is ++ concerned and has already sought out 2 other consults with no answers. Best management? a) Low dose lactulose b) Abdo X ray c) Reassure d) Put mom on “bovine protein-restricted” diet
Reassure · Median daily crying times: 2 week infant is 1 3⁄4 hours · Peaks at 2 3⁄4 hours at 6–8 weeks · Less than 1 hour by 12 week
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You are seeing a 4 month old breastfed infant. She wakes to feed q4-7h during the night. She stools q3-4 days. She goes red in the face while stooling, appears to be straining. What advice to give parents? a) Continue feeding as is b) Start lactulose c) Switch to hydrolyzed formula d) Switch to AA formula
Continue feeding as is
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Mom brings in her 5 year old child for a routine checkup. She mentions her child has one hour of supervised screen time per day. What do you tell her? Normal amount Should have no screen time Should have 30min or less per day Could have at least 2 hours per day
Normal amount For children 2 to 5 years, limit routine or sedentary screen time to about 1 hour or less per day
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You are seeing newborn. Mom is strictly vegan. She is planning to breastfeed exclusively until 6 months of life. Which vitamin is it most important to supplement the baby with? a) B12 b) Iron c) Calcium
B12 - vegan mom's need to provide either b12 fortified fodos or supplements. Breastfeeding by B12-unsupplemented vegan mothers can place an infant at risk for vitamin B12 deficiency.
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Child with autism who is very rigid with routines related to sleep and eating. Presents with increasing irritability, painful legs. On history, you note ecchymoses to bony prominences, perifollicular petechiae, and swollen bleeding gums. What is the diagnosis? Vitamin B12 deficiency Scurvy HSP
Scurvy (Vit C Deficiency) Features of Scurvy: - bleeding gums - petechiae -coiled hairs - hyperkeratosis - ecchymoses -arthralgias
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Baby with suspected trisomy 21 with a petechiael rash, high WBC, anemia, and thrombocytopenia. On exam, has hepatosplenomegaly. What is the most likely reason for his presentation? 57. 3 day old male with T21, platelets 12, WBC 40, hgb 80, hepatosplenomegaly and petechiae. What is most likely diagnosis?
Transient Myeloproliferative Disorder Associated leukocytosis, coagulopathy, hepatomegaly no splenomegaly, low albumin commonly seen in T21
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12 year old embarking upon a vegan diet. Which of the following is the BEST advice to give? Take VB12 supplements Take Zinc supplements Take VitD supplements See a dietician
Refer to dietician May need supplementation of all of above (but definitely vit D).
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A 12-week-old term infant comes into the ED after a 40 second episode where he suddenly was limp and unresponsive with central cyanosis. Mom gave CPR at home. He is now fully back to his baseline and examines well. What do you do? Offer parents CPR training Admit for cardiorespiratory monitoring Metabolic workup EEG and head imaging
Offer parents CPR training -- this is a LOW risk BRUE Low risk: Age > 60 days Gestational age > 32 weeks and post-conception age  > 45 weeks Occurrence of only 1 BRUE (no prior BRUE, no clustered events) Duration of BRUE < 1 minute No CPR by trained medical provider required No concerning historical features No concerning examination findings
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features of low risk BRUE?
recall low risk BRUE: >60d, >32wk, only 1 BRUE, duration <1min, no CPR from healthcare provider (from parent is fine), no concerning features like dysmorphism/seizures or abN neuro exam RECALL that if there is any diagnosis then it is not BRUE
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treatment of low risk BRUE?
hx and exam, observe, no overnight monitoring (4 hr enough), no investigations (could consider ECG and pertussis swab)
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treatment of high risk BRUE?
- CRM monitor for 4 hrs - screen for NAS - observe feed - all high risk: do ECG, RPP, pertussis swab if underimmunized, CBC (look for anemia or polycythemia), blood sugar, gas with lactate. Do more ix if concerns on history or exam.
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Criteria for diagnosing lice?
must detect a living louse presence of nit = previous infection Misdiagnosis is common – must visualize a living louse
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how long to lice live if untreated?
3-4 wks Itching usually starts after 4-6 weeks of inoculation!!!!!!!! they have had lice for a long time before they start itching EWW
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what is pediculosis?
infection with lice
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How is lice transmitted?
direct hair-hair contact, CARPETS at school and PETS are not vectors
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Counselling regarding return to school after lice infection?
Immediately - per CPS: "“Excluding children with nits or live lice from school or child care has no rational medical basis and is not recommended.”
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A child of indigenous descent presents with generalized pruritis that is worse at night, and found to have burrows and erythematous papules on her fingers, wrists and breasts. What is the likely diagnosis and how do we confirm it?
Scabies skin scraping, ink test, dermatoscopy
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what are complications of infection with scabies?
secondary bacterial infections stigmatization depression insomnia financial costs
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what are the risk factors for scabies?
poverty overcrowing bed-sharing indigenous community
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An 18-month-old present with left sided thigh swelling. On workup you find a right sided proximal transphyseal femur fracture. What is the most likely etiology? a. Osteogenesis imperfecta b. Vitamin D resistant rickets c. Non-accidental injury d. Accidental injury/fall
Non-accidental injury transphyseal is a synonym of metaphyseal metaphyseal fractures are high risk for NAI 18mo is minimally ambulating as well Femur fracture in non-ambulatory child is also high risk for NAI -- High-risk fractures for NAI: 1. rib fractures in absence of overt trauma 2. metaphyseal fractures 3. Humerus fractures <18 months (inflicted are more often spiral or oblique, midshaft/proximal location) 4. Femur fracture in non-ambulatory child 5. Scapular, spinous process, sternal fractures Multiple fractures Fractures of different ages Presence of other injuries (bruising - esp trunk, ears, neck, oral trauma) If there is another serious injury, need to have significant traumatic forces clear on history.
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A mother brings her 6-month-old to see you because she would like the MMR vaccine early since she is worried about a Measles outbreak in California where the family will be traveling. What do you recommend? a. MMR is not given under the age of 12 months b. Give 6 month vaccines now and MMR 1 month later c. Give MMR now instead of at 12 months d. Give MMR now and will need her 12 month dose.
Give MMR now and will need her 12 month dose -- standard MMR vaccine schedule is two doses at 12 and 18 months if travelling to high risk zone for measles outbreak, can give as early at 6 months but will still need the standard two doses at 12 and 18 months
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7yo boy with history of repaired TAPVR has difficulty to paying attention in class, often forgets items at home, and is described as hyperactive. You want to start medication to treat ADHD, what should you do before starting? Medication is contraindicated There is no contraindication, start medication immediately ECG Bloodwork
ECG Patients with personal history of cardiac disease or family history of cardiac history should undergo ECG before staring stimulant medications for ADHD
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8 yo boy is often in trouble at school, getting kicked out of class. Doesn’t listen to parents or teachers. Doesn’t follow commands and often doesn’t do what he is told to do. Best management? Methylphenidate CBT Risperidone Parent Skills Teaching
Parent Skills Teaching this patient has oppositional defiant disorder (ODD) Treatment modalities include parent management training (PMT), school-based interventions, individual child therapy, and family therapy
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A 3yo F wakes up every night 1 hour after falling asleep. She does not awaken after midnight. She thrashes in bed, is confused and cries out. She does not remember the episodes in the morning. What is the most appropriate management? Order EEG Wake her up fully during episodes Melatonin Reassurance
Reassurance -- this patient is having Night Terrors Wake up suddenly, very upset (may scream and jump out of bed, appear terrified), often sweating, breathing fast or hear racing. do NOT wake them up - just stay with the child until the night terror is over (usually last 10-20min) and they will go back to sleep. parents will be UNABLE to calm their child night terrors can happen frequently (2-3 times per week)
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7yo male with previously untreated asthma, causing him to miss many days of school. Now his asthma is controlled but his mom says he continues to miss school. On the way to school in the morning, he complains of chest tightness so they go home. At home, symptoms resolve. What is the best next step: A) Gradual return to school B) Start fluoxetine C) Escalate asthma management? D) home school
Gradual return to school -- School Avoidance likely from anxiety but first step is to slowly reintroduce them to school they may need medications if this is unsuccessful
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A girl is taking clarithromycin for an upper respiratory tract infection. She is having significant nausea and vomiting. What should you prescribe her to help with the nausea? Dimenhydrinate Metoclopramide Ondansetron Domperidone
ondansetron metoclopramide and domperidone are for gastroparesis or chemo-induced vomiting dimenhydrinate is antihistamine
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Which of the following would be the most helpful in confirming the diagnosis of ADHD in a 12 year-old male a. Symptoms are only at school b. Difficulty making friends c. Forgets his homework at school d. Spends a lot of time playing video games
B. Difficulty making friends - difficult peer relationships
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Repeat question: a toddler who has had multiple admissions for bronchiolitis that improved with Ventolin. They have had 5 AOMs but are growing well. What is the likely cause? Asthma Immunodeficiency
Asthma Bronchiolitis typically doesn't respond well to Ventolin Technically this case stem does have 2 warning signs for primary immunodeficiency: 2 or more ear infections within 1 year (5 AOM in a 2 year old is 2.5 AOM per year, unless they mean 3 year old by toddler) recurrent viral infections (no specific definition for how many viral infections constitute recurrent, and stem only states “many” admissions for bronchiolitis) However, this toddler is growing well and frequent AOM and bronchiolitis is fairly common
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Neonate develops rash at 36h of life. Well. What is the rash? (multiple pustules on erythematous base on chest and neck) HSV Neonatal pustulosis Erythema toxicum Milia
Erythema Toxicum Neonatorum (ETN) -Typically appears at 24–48 hours of life -Multiple pustules on an erythematous base -Commonly involves the chest, neck, and extremities -Affects 40–70% of full-term neonates; it is benign and self-limited -Resolves by 2 wks of life
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AOM 3 year old 39.1 degrees, red bulging tympanic membrane. Severe pain. Management plan ○ Amox 75-90mg/kg BID x 5 days ○ Amox 75-90mg/kg BID x 10 days ○ Rx for above to be filled in 24 hours if still symptomatic of febrile ○ Reassess in 24-48 hours.
Amox 75-90mg/kg BID x 5 days TID = 45-60mg/kg/d BID = 75-100mg/kg/d <2 year old = 10d >2 year old = 5d Diagnostic criteria: 1. Acute onset symptoms (otalgia) 2. Middle ear fluid (loss of movmt, bony landmarks, air fluid level) and significant inflammation of middle ear 3. OR decrease in TM mobility as visualized with a pneumatic otoscope (good sensitivity and specificity for Middle ear effusion)
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SPO2 for oxygen application for RSV bronchiolitis? a. <96 b. <94 c. <90 d. <88 1 month old with bronchiolitis admitted with poor feeding . On examination there is mild intercostal recession, tachypnea and bilateral wheeze. At what oxygen saturation do you apply oxygen: a. < 88% b. < 90% c. <94% d. <96%
<90%
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It is the beginning of RSV season; who qualifies for RSV prophylaxis? 2mo with cystic fibrosis 4 mo ex 31+6 wk without chronic lung disease 9 mo ex 33+6 wk with chronic lung disease requiring home O2 15 mo old with congenital heart disease, now corrected
9 mo ex 33+6 wk with chronic lung disease requiring home O2
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Neonate born with pustules on face and sacrum. No erythematous base. What is the diagnosis?
Neonatal Pustulosis (Transient Neonatal Pustular Melanosis, TNPM) -- Can be present at birth or appear shortly after. Lesions include pustules and pigmented macules (post-inflammatory hyperpigmentation) after pustules resolve.typically on face and sacrum No erythematous base - distinguishes from erythema toxicum
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Treatment of constipation?
Disimpaction: 1-1.5g/kg/d, enema, or admit to hospital for NG clean out with PEG *digital disimpaction not recommended Maintenance: Peg 0.4-1g/kg/d, behaviour modification (toilet sit 3-10min post-prandially BID, foot stool, praise for sitting, diary). Treat for minimum 6 months. Banalced diet with lots of fluid and fiber (0.5g/kg/d)
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Children who have not mastered reading by the what age will not catch up?
end of grade 3
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what is the most correlated with life-long health trajectories? Occupation Income Literacy
literacy Reading is the single most important activity parents can do with their child to promote eventual reading success.
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how can parents promote early literacy?
reading, speaking, singing and storytelling ‘Serve and return’ interactions help foster emergent literacy skills
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How can physicians support parents in increasing childhood literacy?
Incorporate literacy promotion into your everyday practice Help families develop literacy promoting habits Parents receiving an intervention that promotes reading are 4-10 X more likely to read frequently to their child!! this effect is greatest amongst the poorest children
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what are possible drivers of school difficulties (8)?
* ADHD * Learning Disabilities * Mild Intellectual Disabilities * ODD / Conduct disorder * Sensory impairments (vision, hearing) * Seizures * Mental health – Anxiety, Depression * Autism Spectrum Disorder
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Babies exposed to opioids during pregnancy are at risk for which conditions (5)?
prematurity, low birth weight, spontaneous abortion, SIDS and neurobehavioural abnormalities
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when do symptoms of Neonatal Abstinence Syndrome (NAS) appear?
48-72 hours As late as 5-7 days for Methadone and Buprenorphine
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how long does Neonatal Abstinence Syndrome (NAS) last for? What is the average length of stay for these babies?
10-30 day duration of NAS 15 day is average length of hospital stay
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what is the management principle of Neonatal Abstinence Syndrome (NAS)?
Eat, Sleep, Console judges physiologic distress due to NAS as demonstrated by inability to eat, sleep and console, as well as apnea, seizures, excessive weight loss/poor weight gain Replaces Modified Finnegan scoring
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If a NAS baby is not able to feed, sleep for more than 1 hour or be consoled within 10min, what is the next steps?
Increase Non-Pharm: - feed on demand - swaddle and hold - low stimulation environment - parental presence if still not improved, begin Morphine 0.05 mg/kg/dose q3h can increase by 0.01 each dose
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Two big modifiable risk factors in SIDS?
* Sleeping in prone * Exposure to tobacco prenatally and after birth * ‘Back to sleep’ campaign resulted in 50 % reduction in SIDS
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Two year old presents with 2 day history of cough, wheeze after visiting a friends house. Normal sats. Decreased air entry to right lower lobe. Most important next step? NP Oral dex Chest XR Epi neb
CXR - this is community acquired PNA
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10-year-old boy with ADHD, well controlled on long acting methylphenidate. Issues with going to sleep. Has issues with restless legs and discomfort. Constantly needs to move them around. Sleeps issues long standing per parents. What best to treat? A. Sleep hygiene B. Switch to short acting methylphenidate C. Start iron supplementation D. Start melatonin
Sleep hygiene then send for ferritin
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7-year-old male develops gastroenteritis after visiting his friend one week ago. His friend had similar symptoms. His diarrhea has resolved, but he continues to vomit with partially digested food in the vomitus. Which medication is likely to be the most helpful? a) Omeprazole b) Gravol c) Ondansetron d) Domperidone
Ondansetron
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A new mom is using marijuana and wanting to breastfeed. What do you recommend? a. Recommend breastfeeding, because the benefits outweigh the risks. b. Stop marijuana because breastfeeding is contraindicated with its’ use c. Can breastfeed because the negative impacts of marijuana have been disproven. d. Recommend to stop marijuana because risks to developing neonatal brain are unknown
d. Recommend to stop marijuana because risks to developing neonatal brain are unknown
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What is the most appropriate recommendation to give to a 5-month-old exclusively breastfed infant? A) Prioritize pureed fruits and vegetables at 6 months. B) Perform a routine screen for iron deficiency at 9 months. C) Introduce whole cow's milk at 12 months. D) Supplement with 1 mg/kg/day of elemental iron.
Introduce whole cow's milk at 12 months. 6mo = prioritize iron rich foods (not fruit and veg)
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A 4 year old presents to clinic with irritation and mild photophobia to the right eye. He is rubbing it repeatedly because he feels there is something in the eye. On exam, there is inflammation to the right upper eyelid with some crusting to the base of the eyelashes with no conjunctivitis. What is the most likely diagnosis? A) Chalazion B) Dacryocystitis C) Corneal abrasion D) Blepharitis
Blepharitis Chalazion: obstruction of the ducts of the eyelid. Presentes with a frim, non tender eyelid mass (within the lid). Usually not infected despite swelling and discharge. Management is warm compress Dacryocystitis: infection of the tear sac, or lacrimal sac, that occurs when the nasolacrimal duct is blocked. More common in infants < 1 month old. Management is nasolacrimal massage and systemic antibiotics. Surgical management should be considered if there is respiratory compromise, acute infection or no resolution with conservative management Corneal Abrasion: you would expect to see some conjunctivitis on the examination
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Mother brings her 6-year-old son in as she is concerned about bed wetting. There is no daytime incontinence. What is the MOST appropriate management: No intervention needed Recommended bed wetting alarm Prescribe ddAVP Order a renal ultrasound
No intervention required as mainstay of treatment is education and reassurance
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An 11-year-old male with severe autism presents with a number of concerns. He has had swelling and tenderness in the lower limbs, and inability to walk. He has been confused with gum hypertrophy. He has a very restricted diet with intake mainly pasta, water, and milk. What is the most likely vitamin deficiency? Vitamin C Vitamin B12 Carnitine Vitamin E
Vit C (Scurvy)
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What is the best way to prevent people with disabilities from suffering sexual abuse. a) Less autonomy b) Putting them in day facilities with more supervision c) Better sexual education
Better sexual education
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On examination of an 8-month-old infant, you are unable to palpate the right testicle in the scrotum. What is the BEST next step? A) Refer for surgical correction B) Ultrasound to find the location of the testicle C) Order a karyotype D) Follow up in 2 months
Refer for surgical correction If the exam of an infant between 6 and 12 months of age is consistent with cryptorchidism, they should be referred to a pediatric urologist for surgical consultation orchidopexy needs to occur between 6-18 mo no investigations (such as imaging or karyotype) are recommended for cryptorchidism per the pediatric canadian urological association The only time we recommend repeat evaluation is if an infant has retractile testes (not cryptorchidism), then we re-examine them between 6 and 12 months of age. the stem says that you cannot palpate the testes
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A 14-year-old adolescent boy with ADHD who has been well-controlled on Concerta presents with new-onset derogatory auditory hallucinations and visual hallucinations of eyes watching him. His grades have been dropping since the beginning of the year, and he has been isolating from his friends and refusing to leave his home. He occasionally smokes cannabis. He admits he is terrified of the voices and the strangers he thinks are following him. What is the most appropriate course of action? A) Urgent CBT and family-focused interventions B) Start low-dose olanzapine and follow-up 1 week. C) Stop Concerta and follow-up in 2 weeks. D) Urgent transfer to ED for evaluation and safety assessment.
Urgent transfer to ED for evaluation and safety assessment. Transient psychosis known s/e of cannabinoid use. Additionally, possible but RARE side effect of stimulants.
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A mother has been giving her 5 year old child 1,000 mg of vitamin c daily in hopes to avoid flu symptoms. What is the most likely complication? A) Nephrolithiasis B) hepatitis C) GI bleed D) photosensitivity
Nephrolithiasis
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19. Adolescent girl with bulimia who smokes 1.5 packs/day wants to quit, and is interested in nicotine replacement. Which of the following is a contraindication? There is no contraindication That she still smokes a few cigarettes once in a while That she is <18 years old Her eating disorder
There is no contraindication - those with disordered eating can receive nicotine replacement
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1. Teenage girl, previously with heavy use of marijuana. Now incarcerated. What symptom is most likely? - Palpitations - Abdominal pain - No symptoms - Distorted perceptions 1)b Heavy pot user is incarcerated. Withdrawal symptoms? -none -distorted thinking -palpitations -abdominal pain
Cannabis withdrawal - abdominal pain
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You are seeing a 4-month-old boy in the clinic who you have been following for poor growth. You last saw him 2 weeks ago. What is the expected weight gain? 5g/ day 10g/ day 20g/ day 30g/ day
20g/ day 1-3mo is 30g/d 3-6 mo is 20g/d 6-12 mo is 10g/d
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32. What is the most common side effect of marijuana? Increased insulin secretion Gynecomastia 56. What to tell an adolescent about marijuana side effects: 1. gynecomastia 2. testicular atrophy 3. Insulin stimulation
gynecomastia
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Describe symptoms of cannabis withdrawal disorder (DSM V)
Experiencing at least 2 of 5: Irritability Anxiety Depressed mood Sleep disturbance Appetite changes And at least 1 of 6 physical symptoms: Abdominal pain Shaking Fever Chills Headache Diaphoresis Symptoms usually 24-72h after last use, persist 1-2 weeks (sleep disturbance up to 1 month)
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16. 10 month old recently immigrated from refugee camp in Turkey. He received 3 oral vaccines and 3 injectable vaccines in his lifetime (question did not specify which vaccines). What do you give him at his first visit to you? Pneumococcal + Hib DTAP/IPV/Hib + Pneumococcal DTAP/IPV/Hib + Pneumococcal + Hep B No other vaccination at this time
DTAP/IPV/Hib + Pneumococcal + Hep B
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A child is receiving high dose prednisone for nephrotic syndrome. He is due for his DPTP-Hib. When can you give it? Today 1 month 6 months 11 months 53. 5 yo girl diagnosed with nephrotic syndrome and on high dose steroids. You’ve counselled that she shouldn’t receive any live vaccines. What should she get now? HPV vaccine HAV vaccine Pneumococcal polysaccharide (23-valent) vaccine Meningococcal conjugate vaccine
Live vaccines may be given immediately on discontinuation of high dose steroid therapy if duration was < 14 days. Today - pneumococcal polysacharide (23-valent vaccine) (recommended for nephrotic syndrome patients due to them voiding out antibodies).
272
8-year-old female with a history of behavioral problems. She used to eat her food in a certain order, now she refuses to have her food touch each other on the plate. In school she refuses to be close to her peers and she refuses to walk on a certain pattern on the sidewalk. Which questionnaire Would you use to screen her? SNAP SCARED (anxiety) Yale children OCD Eating Attitude Test
this is OCD Children’s Yale-Brown Obsessive Compulsive Scale (CY-BOCS) for 5 to 18 years classic features of OCD is not letting food touch each other, order of food to be eaten and not stepping on cracks
273
When is steroid therapy not a contraindication to immunization with live vaccines?
- steroid therapy is short-term (<14 days) - low-to-moderate dose (prednisone equivalent of less than 2 mg/kg/day or less than 20 mg/day if weight > 10 kg) - is physiologic replacement therapy or administered topically, inhaled, or locally injected (e.g., joint injection). - An exception is live attenuated virus, which is contraindicated in individuals with severe asthma who are currently receiving high dose inhaled steroids.
274
A 3.5-year-old male visits your office. In addition to noticing echolalia, what additional feature would make you concerned about a diagnosis of autism? Walking 15 months Parallel play with siblings Temper Tantrums Hyperactivity
Parallel Play with Siblings (the most delayed and in keeping with ASD) Parallell play is typical milestone at 18 mo, cooperative, pretend play is typical at 3 yrs, and elaborate fantasy play and preferred friend at 4 years
275
Teenager with ADHD and family history of substance use. Which medication would you start him on? (gave both generic medication and brand names) Methylphenidate Strattera Vyvanse Intuniv
Strattera no stimulants with substance abuse CPS statement mentions both atomoxetine and guanfacine as options in history of substance abuse --> however AAP has atomoxetine listed as primary non-stimulant option when stimulants are contraindicated
276
Parents bring in their 8 year old child to see you because of recurrent abdominal pain and headaches. During the visit, the parents keep interrupting and insulting each other. Your suspect the child has been exposed to intimate partner violence. What is the next best step? A) Ask the parents if there has been intimate partner violence in the home B) Refer for family therapy C) Refer to child protective services D) Arrange to meet with the child and each parent individually
Arrange to meet with the child and parent individually (concern for intimate partner violence) CPS: Recognizing and responding to children with suspected exposure to intimate partner violence between caregivers. CPS: Supporting the mental health of children and youth of separating parents
277
13 year old boy with a history of chronic abdo pain and declining school performance. In your visit, he is not talking much and mom is interrupting/doing most of the talking. What is the next step? Keep parents in the room and continue visit. He is too young to give a history without his parent there. Ask mother to leave Ask if he wants to talk with you alone Say that it is routine that all adolescents have time alone during appointments
Say that it is routine that all adolescents have time alone with appointments.
278
You are a locum pediatrician in a small rural community. You notice that many preschool children have cavities requiring operative correction. The nearest dentist is 1 hour away. There is limited access to clean water. What is the most appropriate recommendation for community leaders on this issue: Give all children toothbrushes at the start of school. Provide funds for all families to go to the dentist twice per year. Bring a dental therapist in monthly to the local community health center. Ensure access to clean distilled water for formula mixing.
Bring a dental therapist in monthly to the local community health center.
279
2 year old presenting with crying or frustration when told no and she falls to the ground kicking and banging her head. What is the most appropriate advice regarding her behaviour? Warn her that you will put her in timeout Provide a protective helmet Start oral iron Ignore the behavior while ensuring safety
ignore behaviour while ensuring safety Time out – not great <2y, 1 min per child age Head Banging is ++ common UNUSUAL IF >5y – consider ASD, anxiety, abuse
280
Kid with ADHD who does not swallow pills and will not take chewable pills. What to prescribe? Biphentin Concerta Strattera Intuniv
Biphentin Beads can be sprinkled on soft food
281
1mo baby with head turn/head tilt (essentially describing torticollis). Was delivered by c-section due to breech presentation. What is the most appropriate management? Head u/s Occupational therapy Physical therapy Reassure
physical therapy
282
picky eater - how to manage?
parents choose WHAT to offer kids choose HOW MUCH meals (and nutrient dense snacks ok as long as doesn't impact next meal, no grazing) should be enjoyable :) limit table time to 20 min then remove all food, offer again at next meal/snack stimulate update with play/exercise for 15min pre-meals
283
Patient seeing you for health surveillance with achondroplasia at 1 month of age. What do you have to do as part routine surveillance? ECG EEG MRI brain Renal ultrasound
MRI brain
284
Intranasal influenza vaccine (LAIV; FluMist) contraindications?
Contraindications - immune compromised - severe asthma on high dose ICS or recent oral steroids, or exacerbation within the last 7 days - <2yrs - on aspirin
285
Woman 28 weeks pregnant, with 2 and 5 year old children at home. What is the best way to prevent influenza in the new baby within the first 6 months of life? Inactivated vaccine for mom right now Inactivated vaccine for mom after birth Inactivated vaccine for dad and two kids, no vaccine for mom Inactivated vaccine for dad, live attenuated vaccine for two kids, no vaccine for mom
Inactivated vaccine for mom right now; Either inactivated influenza vaccine or live attenuated influenza vaccine may be used for children and youth 2 to 17 years old who are not immunocompromised
286
child with concussion. When can she return to play? Back at school full time with no symptoms and no accommodations After symptom free for 7 days
Back at school full time with no symptoms and no accommodations To begin Return To Play: Successful return to school Symptom free and off any meds prescribed to treat the concussion Normal neuro exam Back at baseline balance and cognitive performance measures
287
What is the minimum requirement to sit in a car with a seatbelt and no car seat? 135cm 145cm 150cm 155cm
145cm Must be at least 145cm tall to start safely sitting in the car without a booster seat
288
How long should a child be rear-facing in a car for?
Until at least 2 years old. Once they have outgrown the larger rear-facing car seat and is at least 2 years old, they can move to a forward facing car seat with a 5 point harness
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17 year old male with history of enthesis related JIA comes to your office. Just had a new baby girl with his girlfriend and would like to quit smoking for her sake. What puts him MOST at risk of not being able to quit? Chronic illness Male gender Older adolescent Parenthood
Chronic illness