COMPONENT PREPARATION AND THERAPY Flashcards
(30 cards)
provides the necessary/correct component that should be given to the patient
Transfusion Therapy
Has a critical value for many types of diseases and conditions
Transfusion Therapy
When targeting a certain blood component, it also allows minimization of any exposure that could lead to adverse_______ or _______
reaction or complication
Component preparation is directly from the _______; either modified or unmodified component can be prepared from it.
whole blood
A single blood donation can provide transfusion therapy to multiple patients in the form of (4)
red blood cells (RBCs), platelets, fresh-frozen plasma, and cryoprecipitate.
Most important factor to consider in preparing a component and transfusion therapy is the ___________
patient’s condition.
Equipment in the Component Manufacturing Laboratory (6)
- Centrifuge
- Plasma Expressors
- Tubing Sealers
- Sterile Connection Devices
- Storage Devices
- Quadruple Bag
Component manufacturing centrifuges are typically either large floor units or large table top units that can spin a maximum of ______ units of whole blood at once.
6 to 12 units
Purpose of centrifuge
Separate red blood cells from plasma and other components
Centrifugation depends on the following conditions (2)
o Length/duration
o Speed
Red blood cells + plasma
5,000 x g, 5 minutes (Soft Spin)
Red blood cells + platelet-rich plasma
2,000 g, 3 minutes
Harvesting platelets or Cryoprecipitate from plasma
5,000 x g, 7 minutes (Hard Spin)
*PRP (Platelet-rich plasma)
platelets are not entirely removed from the plasma
METHODS OF CENTRIFUGATION (2)
- Intermittent Flow Centrifugation (IFC)
- Continuous Flow Centrifugation (CFC)
Blood is processed in batches or cycles; Whole blood is drawn from an individual with the assistance of a pump
Intermittent Flow Centrifugation (IFC)
To keep the blood from clotting in IFC, an ___________ is mixed with the blood as it is pumped into a centrifuge bowl or chamber through the ______
anticoagulant;inlet port
In a _______________________ procedure, the processes of blood withdrawal, processing, and reinfusion are performed simultaneously in an ongoing manner.
continuous flow centrifugation (CFC)
T/F. In CFC, compleye a cycle first before beginning the next one
truelala
In CFC, Blood is drawn and returned continuously during a procedure, _________________ sites are necessary
two venipuncture
Mechanical devices that apply pressure to the blood bag, which allows
blood components to flow from one bag to another by way of the integrated tubing system
PLASMA EXPRESSORS
The tubing that connects blood bags is usually made of ____________
polyvinyl chloride (PVC)
______ are resistant to damages from temperatures, etc.
PVCs
Allow two separate blood bags to be connected via their PVC tubing without breaching the integrity of either container.
Each piece of tubing is placed in a channel and clamped.
STERILE CONNECTION DEVICES