LEUKODEPLETED/LEUKOREDUCED RED BLOOD CELLS

Question 1

Red blood cell component in which the white blood cells have been removed/reduced

Answer 1

LEUKODEPLETED/LEUKOREDUCED RED BLOOD CELLS

Question 2

85% remaining RBCs

Answer 2

LEUKODEPLETED/LEUKOREDUCED RED BLOOD CELLS

Question 3

LEUKODEPLETED/LEUKOREDUCED RED BLOOD CELLS indicationns (3)

Answer 3

 Anemia with history of febrile reactions
 To decrease alloimmunization to WBC or HLA antigens or CMV transmission
 It should have the residual WBCs (5x106)

Question 4

In FNHTR, there is an increase or______ temperature after ______ of transfusion

Answer 4

> 1°C; 4 hours

Question 5

LEUKODEPLETED/LEUKOREDUCED RED BLOOD CELLS SHELF LIFE
 Closed system –
 Open System –

Answer 5

 Closed system – same with Packed RBC (depends on the anticoagulant)
 Open System – 24 hours

Question 6

Means Of Leukocyte Removal (3)

Answer 6

1. Means of centrifugation
2. Washing procedures (using saline or glycerol)
3. Mechanical separation (use of leukoreduction filters)

Question 7

Sizes of Filters
 1st generation filter –
 2nd generation filter –
 3rd generation filter –

Answer 7

 1st generation filter – 170 µm
 2nd generation filter – 20-40 µm
 3rd generation filter – 3-log filter

Question 8

can be separated during or immediately after collection

Answer 8

Pre-storage

Question 9

separation must be made _____

Answer 9

before storage.

Question 10

can be separated at the time of transfusion

Answer 10

Post-storage