Conjunctival Growths

Question 1

What is important to keep in mind about how Pemphigus Vulgaris affects the eye?

Answer 1

It typically doesn’t affect the eye, but when it does it creates DES

Question 2

Tell me everything you know about Cicatricial Pemphygoid

Answer 2

Bilateral
Females / Old people
Creates DES (aqueous or mucous)
Most cases have oro-pharyngeal involvement

Question 3

Tell me all the ways Ocular Cicatricial Pemphygoid affects the eye

Answer 3

Shortens palpebral fissure
Shortens fornix
Tyalosis
Madarosis
Poliosis
Lash metaplasia

Question 4

Why is Ocular Cicatricial Pemphygoid more damaging to the eye than Pemphigus Vulgaris?

Answer 4

OCP fucks up the basement membrane which scars the substantia propria and goblet cells

Question 5

What is Pseudopemphigoid?

Answer 5

Drug-induced autoimmune reaction which attacks mucosal basement membrane antigens.
Includes Erythema Multiforme and TEN / SJS

Question 6

Which is usually worse: Erythema Multiforme or TEN / SJS?

Answer 6

TEN / SJS

Question 7

How can you differentiate TEN and SJS?

Answer 7

YOU CAN’T THEY’RE THE SAME THING BAAAHAHAHAHAHHA

Question 8

Distinguish the difference in causes between PV v OCP v Pseudopemphigoid

Answer 8

PV - autoimmune attack against keratinocytes
OCP - autoimmune attack against basement membranes
Pseudopemphigoid - allergic reaction to a drug

Question 9

What population of people typically get Pemphigoid Vulgaris?

Answer 9

Jewish / Mediterranean populations

Question 10

What is Bitot’s Spot associated with?

Answer 10

Vitamin A deficiency