Conn's Syndrome

Question 1

What is Conn’s syndrome?

What is Conn’s also known as?

Answer 1

Type of hyperaldosteronism caused by adrenal adenoma

Primary hyperaldosteronism

Question 2

What would be found on U&Es and on an ABG in patients with Conn’s syndrome?

Answer 2

Hypokalaemia

Metabolic alkalosis

Question 3

What is the first-line investigation for Conn’s?

Answer 3

Aldosterone/Renin ratio

Question 4

What is the treatment for Conn’s syndrome?

Answer 4

Bilateral adrenal hyperplasia -> Spirinolactone to increase K+

Unilateral benign adenoma -> Surgery

Question 5

What is the main symptom of Conn’s?

Answer 5

Hypertension

Question 6

What is aldosterone?
Where it produced?
Function of aldosterone?

Answer 6

Mineralocorticoid steroid

Adrenal glands

Reabsorbs sodium
Secretes potassium into urine (lets go of potassium)
secretes hydrogen into urine (Lets go of hydrogen)

Question 7

Most common cause of primary hyperaldosteronism?

Answer 7

Bilateral adrenal hyperplasia