Connective Flashcards

1
Q

Provide a matrix that supports and physically connects other tissues and cells together to form the organs of the body

A

Connective tissue

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2
Q

2 main classes of connective tissue proper

A
  1. Loose connective tissue
  2. Dense connective tissue
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3
Q

3 main classes of cartilage

A

Hyaline cartilage
Fibrocartilage
Elastic cartilage

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4
Q

2 main classes of bone

A

Compact and spongy bone

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5
Q

Key cell of connective tissue

A

Fibroblasts

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6
Q

What are the cells of connective tissue

A

Fibroblasts
Adipocytes
Macrophages and mononuclear phagocyte system
Mast cells
Plasma cells
Leuckocytes

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7
Q

Synthesize and secrete collagen and elastin

A

Fibroblasts

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8
Q

Specialized cells for storage of triglycerides

A

Adipocytes

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9
Q

Used for turnover, phagocytosis of dead cells and debris, and antigen presentation to lymphocytes

A

Macrophages and mononuclear phagocyte system

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10
Q

cells same as macrophages that is located in the liver

A

kupffer cells

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11
Q

same as macrophages that is located in the central nervous system

A

microglial cells

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12
Q

filled with basophilic secretory granules that often obscure the central nucleus

A

mast cells

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13
Q

What are the 6 molecules from secretory granules

A

heparin
histamine
protease
eosinophil and neutrophil
cytokines
phospholipid

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14
Q

lymphocyte-derived, antibody-producing cells

A

plasma cells

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15
Q

function in connective tissue only for a few hours or days and then undergo apoptosis

A

leukocytes

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16
Q

5 cardinal signs of inflammation

A

redness
heat
swelling
pain
loss of function

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17
Q

composed of collagen reticular elastic

A

Protein fiber

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18
Q

composition of fiber

A

collagen
reticular fibers
elastic fibers

19
Q

ground susbtances

A

glycoaminoglycans
proteoglycans
multiadhesive glycoproteins

20
Q

most important and abundant fibers of connective tissue

21
Q

Adds soluble galactosine and glucosil sugar

A

glycosilation

22
Q

alpha chains subunits of collagen

A

fibril-forming collagens
network-forming collagens
linking/anchoring collagens

23
Q

found in delicate connective tissue of many organs, notably in the immune system

A

reticular fibers

24
Q

also called elastic lamellae in arteries

A

elastic fibers

25
acts as both a lubricant and a barrier to the penetration of invaders
ground substance
26
the watery, largely unstained extracellular material that is more abundant than fibers in some types of connective tissue proper
ground susbtance
27
are long polymers of repeating disaccharide units, usually a hexosamine and uronic acid
glycosaminodglycans
28
best studies proteoglycans
aggrecan
29
key proteoglycan in all basal laminae
perlecan
30
consist of a core protein to which are covalently attached various numbers and combinations of the sulfated GAGs
proteoglycans
31
4 major GAGs
Dermatan sulfate Chondroitin sulfate Keratan sulfate Heparan sulfate
32
large molecules with branched oligosaccharide chains and allow adhesion of cells to their substrate
multiadhesive glycoprotein
33
Water in the ground substance of connective tissue
interstitial fluid
34
layer beneath the epithelial lining of many organs and filling the spaces between fibers of muscle and nerve
loose connective tissue
35
generally works to hold organs, anatomic structures, and tissues in place
loose connective tissue
36
a clear predominance of bundled type I collagen fibers over ground substance
dense connective tissue
37
protects organs and strengthens them structurally
dense connective tissue
38
bundles of collagen fibers appear randomly interwoven, with no definite orientation
dense irregular connective tissue
39
long, parallel bundles of collagen fibers fill the spaces between the elongated nuclei of fibrocytes
dense regular connective tissue
40
great resistance to prolonged or repeated from the same direction
dense regular connective tissue
41
great resistance to prolonged or repeated stresses from the same direction
dense regular connective tissue
42
principal component of the fetal umbilical cord, where it is referred to as
Wharton's jelly
43
characterized by abundant fibers of type III collagen
reticular connective tissue
44
most abundant in certain lymphoid organs where the fibers form attachment sites for lymphocytes and other immune cells
reticular connective tissue