Connective Tissue 1 Flashcards
(36 cards)
The function of connecting tissue….
Mechanical strength
General structure
Space filling
Physical and metabolic support
Give three properties of connective tissue and explain them.
Elasticity- usually elastin, allow it to go back to its original form.
Tensile strength- Collagen, Resist pulling, streaching and tearing
Volume- usually made of large glycoprotein and carbohydrates, For the formation of ground substances
Extracellular matrix is known as what?
Combination of matrix fibers and collagen
Fibroblasts are derived from which fetal tissue?
Mesenchyme
Specialised tissue for storage
Adipocytes
packing and wrapping of material
Loose connective tissue
Provide tough physical support
Dense connective tissue
What are fibroblast and myofibroblast
Are both derived from mesenchyme
for synthesis, recycling, and maintenance of extracellular functioning.
Describe the structure of fibroblast
Nuclei are condensed and elongated in a direction of a fiber
Cytoplasm barely visible
Cells are thin and long
Cytoplasm recesses extend to matrix
What are myofibroblast
Myofibroblasts are activated forms of fibroblasts associated with contractile function and the role of repair. They have prominent nucleoli and the nuclei is large and cytoplasmic is extensive and basophilic. Basophilic extracellular matrix is prominent. They also secrete matrix.
What are collagen
are found in most supporting tissue, Provide tensile strength, resist pulling, stretching, and tearing. They can form fiber, mesh/network some cell membrane material. There are 28 collagen, grouped according to their morphology, amino acid composition and physical property.
Main structural collagen, Found in fibrous tissues. Stained pink using Haematoxylin and Eosin. Fibers vary in orientation, size and density and they use light microscopy.
Collagen 1
Consists of fibrils of collagen in the ground substance. Found in hyaline cartilage.
Collagen II
Often termed reticulin, prominent in highly cellular tissue, Forms a delicate branched reticular supporting meshwork.
Collagen III
Found in the basement membrane. Forms mesh/network of collagen.
Collagen 4
specialized anchoring fibrils which link basement membrane and extracellular matrix
Collagen VII
Describe the elastin
Arranged in discontinuous sheet in the extracellular matrix. They are stretching and elastic recoil. Found in blood vessels, and lungs, they are important in blood vessels, and they are capable of bringing back the shape after the deformation of the structure. They have a different functions then they will be found in different proportions. Elastin fibre are eosinophils and bent light, they have special elastin stains.
Amorphous, transparent semi-solid gel material. They have glycoproteins and complex carbohydrates and water-binding availability.
Ground substances.
Differentiates the stain of ground substances in acian blue and H & E.
In alcian blue they are stained wispy blue in the background of pink stained collagen fibers and in H & E they are stained pale blue in the collagen.
made up of type IV collagen and stained by PAS
Basement membrane
functions of basement membrane
- binding of epithelium tissue
- Differentiation of epithelial and growth
- Regulates permeability
Sheet like arrangements of extra-cellular matrix proteins.
Act as an interface (in-between) between support tissues and epithelial/parenchymal tissues.
Basement membrane.
Are adipose derived from mesenchyme true or false?
True
what are adipose
are supportive tissue for the storage of adipocytes.
